Polymorphism, Single-Stranded Conformational
"Polymorphism, Single-Stranded Conformational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
| Descriptor ID |
D018807
|
| MeSH Number(s) |
G05.365.795.600
|
| Concept/Terms |
Polymorphism, Single-Stranded Conformational- Polymorphism, Single-Stranded Conformational
- Polymorphism, Single Stranded Conformational
- SSCP
- Single-Stranded Conformational Polymorphism
- Conformational Polymorphism, Single-Stranded
- Conformational Polymorphisms, Single-Stranded
- Polymorphisms, Single-Stranded Conformational
- Single Stranded Conformational Polymorphism
- Single-Stranded Conformational Polymorphisms
|
Below are MeSH descriptors whose meaning is more general than "Polymorphism, Single-Stranded Conformational".
Below are MeSH descriptors whose meaning is more specific than "Polymorphism, Single-Stranded Conformational".
This graph shows the total number of publications written about "Polymorphism, Single-Stranded Conformational" by people in this website by year, and whether "Polymorphism, Single-Stranded Conformational" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Polymorphism, Single-Stranded Conformational" by people in Profiles.
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Primary human hepatocytes in spheroid formation to study hepatitis C infection. J Surg Res. 2006 Jan; 130(1):52-7.
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Designing and implementing quality control for multi-center screening of mutations in the ATM gene among women with breast cancer. Hum Mutat. 2003 May; 21(5):542-50.
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Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines. Biochem J. 2002 Nov 01; 367(Pt 3):741-50.
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Mutations of the beta- and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas. Br J Cancer. 2001 Jul 06; 85(1):64-8.
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Gestational diabetes mellitus and gene mutations which affect insulin secretion. Diabetes Res Clin Pract. 1997 Jun; 36(3):135-41.