David G. Priest

Title
InstitutionMedical University of South Carolina
DepartmentBiochemistry and Molecular Biology
Address
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    1. Ohno M, Ando T, Priest DG, Taniguchi Y, Ohno M, Ando T, Priest DG, Taniguchi Y. Hi-CO: 3D genome structure analysis with nucleosome resolution. Nat Protoc. 2021 07; 16(7):3439-3469. PMID: 34050337.
      Citations:    
    2. Priest DG, Bernardini A, Lou J, Mantovani R, Hinde E, Priest DG, Bernardini A, Lou J, Mantovani R, Hinde E. Live cell dynamics of the NF-Y transcription factor. Sci Rep. 2021 05 26; 11(1):10992. PMID: 34040015; PMCID: PMC8155045.
      Citations:    
    3. Lou J, Priest DG, Solano A, Kerjouan A, Hinde E, Lou J, Priest DG, Solano A, Kerjouan A, Hinde E. Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break. Nat Commun. 2020 11 13; 11(1):5776. PMID: 33188174; PMCID: PMC7666136.
      Citations:    
    4. Ormsby AR, Cox D, Daly J, Priest D, Hinde E, Hatters DM, Ormsby AR, Cox D, Daly J, Priest D, Hinde E, Hatters DM. Nascent mutant Huntingtin exon 1 chains do not stall on ribosomes during translation but aggregates do recruit machinery involved in ribosome quality control and RNA. PLoS One. 2020; 15(7):e0233583. PMID: 32735619; PMCID: PMC7394408.
      Citations:    
    5. Priest DG, Solano A, Lou J, Hinde E, Priest DG, Solano A, Lou J, Hinde E. Fluorescence fluctuation spectroscopy: an invaluable microscopy tool for uncovering the biophysical rules for navigating the nuclear landscape. Biochem Soc Trans. 2019 08 30; 47(4):1117-1129. PMID: 31278154.
      Citations:    
    6. Ohno M, Ando T, Priest DG, Kumar V, Yoshida Y, Taniguchi Y, Ohno M, Ando T, Priest DG, Kumar V, Yoshida Y, Taniguchi Y. Sub-nucleosomal Genome Structure Reveals Distinct Nucleosome Folding Motifs. Cell. 2019 01 24; 176(3):520-534.e25. PMID: 30661750.
      Citations:    
    7. Ohno M, Priest DG, Taniguchi Y, Ohno M, Priest DG, Taniguchi Y. Nucleosome-level 3D organization of the genome. Biochem Soc Trans. 2018 06 19; 46(3):491-501. PMID: 29626147.
      Citations:    
    8. Priest DG, Tanaka N, Tanaka Y, Taniguchi Y, Priest DG, Tanaka N, Tanaka Y, Taniguchi Y. Micro-patterned agarose gel devices for single-cell high-throughput microscopy of E. coli cells. Sci Rep. 2017 12 21; 7(1):17750. PMID: 29269838; PMCID: PMC5740163.
      Citations:    
    9. Priest DG, Kumar S, Yan Y, Dunlap DD, Dodd IB, Shearwin KE, Priest DG, Kumar S, Yan Y, Dunlap DD, Dodd IB, Shearwin KE. Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells. Proc Natl Acad Sci U S A. 2014 Oct 21; 111(42):E4449-57. PMID: 25288735; PMCID: PMC4210295.
      Citations:    
    10. Murchland I, Ahlgren-Berg A, Priest DG, Dodd IB, Shearwin KE, Murchland I, Ahlgren-Berg A, Priest DG, Dodd IB, Shearwin KE. Promoter activation by CII, a potent transcriptional activator from bacteriophage 186. J Biol Chem. 2014 Nov 14; 289(46):32094-32108. PMID: 25294872; PMCID: PMC4231686.
      Citations:    
    11. Priest DG, Cui L, Kumar S, Dunlap DD, Dodd IB, Shearwin KE, Priest DG, Cui L, Kumar S, Dunlap DD, Dodd IB, Shearwin KE. Quantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and ? repressors. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):349-54. PMID: 24344307; PMCID: PMC3890862.
      Citations:    
    12. St-Pierre F, Cui L, Priest DG, Endy D, Dodd IB, Shearwin KE, St-Pierre F, Cui L, Priest DG, Endy D, Dodd IB, Shearwin KE. One-step cloning and chromosomal integration of DNA. ACS Synth Biol. 2013 Sep 20; 2(9):537-41. PMID: 24050148.
      Citations:    
    13. Oleinik NV, Krupenko NI, Priest DG, Krupenko SA, Oleinik NV, Krupenko NI, Priest DG, Krupenko SA. Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression. Biochem J. 2005 Nov 01; 391(Pt 3):503-11. PMID: 16014005; PMCID: PMC1276951.
      Citations:    
    14. Hooijberg JH, Peters GJ, Assaraf YG, Kathmann I, Priest DG, Bunni MA, Veerman AJ, Scheffer GL, Kaspers GJ, Jansen G, Hooijberg JH, Peters GJ, Assaraf YG, Kathmann I, Priest DG, Bunni MA, Veerman AJ, Scheffer GL, Kaspers GJ, Jansen G. The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis. Biochem Pharmacol. 2003 Mar 01; 65(5):765-71. PMID: 12628490.
      Citations: 13     Fields:    Translation:HumansCells
    15. Rothem L, Ifergan I, Kaufman Y, Priest DG, Jansen G, Assaraf YG, Rothem L, Ifergan I, Kaufman Y, Priest DG, Jansen G, Assaraf YG. Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines. Biochem J. 2002 Nov 01; 367(Pt 3):741-50. PMID: 12139489; PMCID: PMC1222927.
      Citations: 14     Fields:    Translation:HumansCells
    16. van der Wilt CL, Backus HH, Smid K, Comijn L, Veerman G, Wouters D, Voorn DA, Priest DG, Bunni MA, Mitchell F, Jackman AL, Jansen G, Peters GJ, van der Wilt CL, Backus HH, Smid K, Comijn L, Veerman G, Wouters D, Voorn DA, Priest DG, Bunni MA, Mitchell F, Jackman AL, Jansen G, Peters GJ. Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors. Cancer Res. 2001 May 01; 61(9):3675-81. PMID: 11325838.
      Citations: 27     Fields:    Translation:Animals
    17. McLeod HL, Cassidy J, Powrie RH, Priest DG, Zorbas MA, Synold TW, Shibata S, Spicer D, Bissett D, Pithavala YK, Collier MA, Paradiso LJ, Roberts JD, McLeod HL, Cassidy J, Powrie RH, Priest DG, Zorbas MA, Synold TW, Shibata S, Spicer D, Bissett D, Pithavala YK, Collier MA, Paradiso LJ, Roberts JD. Pharmacokinetic and pharmacodynamic evaluation of the glycinamide ribonucleotide formyltransferase inhibitor AG2034. Clin Cancer Res. 2000 Jul; 6(7):2677-84. PMID: 10914709.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    18. Jansen G, Peters GJ, Pinedo HM, Priest DG, Assaraf YG, Jansen G, Peters GJ, Pinedo HM, Priest DG, Assaraf YG. Re: Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo. J Natl Cancer Inst. 1999 Dec 01; 91(23):2047-50. PMID: 10580033.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    19. Raghunathan K, Priest DG, Raghunathan K, Priest DG. Modulation of fluorouracil antitumor activity by folic acid in a murine model system. Biochem Pharmacol. 1999 Sep 01; 58(5):835-9. PMID: 10449194.
      Citations: 3     Fields:    Translation:Animals
    20. Jansen G, Barr H, Kathmann I, Bunni MA, Priest DG, Noordhuis P, Peters GJ, Assaraf YG, Jansen G, Barr H, Kathmann I, Bunni MA, Priest DG, Noordhuis P, Peters GJ, Assaraf YG. Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration. Mol Pharmacol. 1999 Apr; 55(4):761-9. PMID: 10101035.
      Citations: 12     Fields:    Translation:AnimalsCells
    21. Priest DG, Schmitz JC, Bunni MA, Priest DG, Schmitz JC, Bunni MA. Accumulation of plasma reduced folates after folic acid administration. Semin Oncol. 1999 Apr; 26(2 Suppl 6):38-41. PMID: 10598553.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    22. Jansen G, Mauritz R, Drori S, Sprecher H, Kathmann I, Bunni M, Priest DG, Noordhuis P, Schornagel JH, Pinedo HM, Peters GJ, Assaraf YG, Jansen G, Mauritz R, Drori S, Sprecher H, Kathmann I, Bunni M, Priest DG, Noordhuis P, Schornagel JH, Pinedo HM, Peters GJ, Assaraf YG. A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance. J Biol Chem. 1998 Nov 13; 273(46):30189-98. PMID: 9804775.
      Citations: 32     Fields:    Translation:HumansCells
    23. Liu Y, Raghunathan K, Hill C, He Y, Bunni MA, Barredo J, Priest DG, Liu Y, Raghunathan K, Hill C, He Y, Bunni MA, Barredo J, Priest DG. Effects of antisense-based folypoly-gamma-glutamate synthetase down-regulation on reduced folates and cellular proliferation in CCRF-CEM cells. Biochem Pharmacol. 1998 Jun 15; 55(12):2031-7. PMID: 9714324.
      Citations: 2     Fields:    Translation:HumansCells
    24. Raghunathan K, Schmitz JC, Priest DG, Raghunathan K, Schmitz JC, Priest DG. Impact of schedule on leucovorin potentiation of fluorouracil antitumor activity in dietary folic acid deplete mice. Biochem Pharmacol. 1997 Apr 25; 53(8):1197-202. PMID: 9175725.
      Citations: 4     Fields:    Translation:Animals
    25. Raghunathan K, Schmitz JC, Priest DG, Raghunathan K, Schmitz JC, Priest DG. Disposition of leucovorin and its metabolites in dietary folic acid-deplete mice - comparison between tumor, liver, and plasma. Cancer Chemother Pharmacol. 1997; 40(2):126-30. PMID: 9182833.
      Citations: 1     Fields:    Translation:Animals
    26. Jansen G, Mauritz RM, Assaraf YG, Sprecher H, Drori S, Kathmann I, Westerhof GR, Priest DG, Bunni M, Pinedo HM, Schornagel JH, Peters GJ, Jansen G, Mauritz RM, Assaraf YG, Sprecher H, Drori S, Kathmann I, Westerhof GR, Priest DG, Bunni M, Pinedo HM, Schornagel JH, Peters GJ. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells. Adv Enzyme Regul. 1997; 37:59-76. PMID: 9381986.
      Citations: 3     Fields:    Translation:HumansCells
    27. Miotti S, Facheris P, Tomassetti A, Bottero F, Bottini C, Ottone F, Colnaghi MI, Bunni MA, Priest DG, Canevari S, Miotti S, Facheris P, Tomassetti A, Bottero F, Bottini C, Ottone F, Colnaghi MI, Bunni MA, Priest DG, Canevari S. Growth of ovarian-carcinoma cell lines at physiological folate concentration: effect on folate-binding protein expression in vitro and in vivo. Int J Cancer. 1995 Nov 03; 63(3):395-401. PMID: 7591238.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    28. Lenz HJ, Hill C, Danenberg KD, Leichman LL, Priest DG, Danenberg PV, Lenz HJ, Hill C, Danenberg KD, Leichman LL, Priest DG, Danenberg PV. Rapid quantitative PCR for determination of relative gene expressions in tissue specimens. PCR Methods Appl. 1995 Apr; 4(5):305-8. PMID: 7580920.
      Citations: 1     Fields:    Translation:HumansCells
    29. Pizzorno G, Moroson BA, Cashmore AR, Russello O, Mayer JR, Galivan J, Bunni MA, Priest DG, Beardsley GP, Pizzorno G, Moroson BA, Cashmore AR, Russello O, Mayer JR, Galivan J, Bunni MA, Priest DG, Beardsley GP. Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM. Cancer Res. 1995 Feb 01; 55(3):566-73. PMID: 7834626.
      Citations: 5     Fields:    Translation:HumansCells
    30. Liu Y, Bhalla K, Hill C, Priest DG, Liu Y, Bhalla K, Hill C, Priest DG. Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell line. Biochem Pharmacol. 1994 Sep 15; 48(6):1265-72. PMID: 7945420.
      Citations: 21     Fields:    Translation:HumansCells
    31. Schmitz JC, Grindey GB, Schultz RM, Priest DG, Schmitz JC, Grindey GB, Schultz RM, Priest DG. Impact of dietary folic acid on reduced folates in mouse plasma and tissues. Relationship to dideazatetrahydrofolate sensitivity. Biochem Pharmacol. 1994 Jul 19; 48(2):319-25. PMID: 8053927.
      Citations: 10     Fields:    Translation:AnimalsCells
    32. Barredo JC, Synold TW, Laver J, Relling MV, Pui CH, Priest DG, Evans WE, Barredo JC, Synold TW, Laver J, Relling MV, Pui CH, Priest DG, Evans WE. Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia. Blood. 1994 Jul 15; 84(2):564-9. PMID: 7517720.
      Citations: 28     Fields:    Translation:HumansCellsCTClinical Trials
    33. Schmitz JC, Stuart RK, Priest DG, Schmitz JC, Stuart RK, Priest DG. Disposition of folic acid and its metabolites: a comparison with leucovorin. Clin Pharmacol Ther. 1994 May; 55(5):501-8. PMID: 8181194.
      Citations: 4     Fields:    Translation:Humans
    34. Bunni MA, Sirotnak FM, Otter GM, Priest DG, Bunni MA, Sirotnak FM, Otter GM, Priest DG. Disposition of leucovorin and its metabolites in the plasma, intestinal epithelium, and intraperitoneal L1210 cells of methotrexate-pretreated mice. Cancer Chemother Pharmacol. 1994; 34(6):455-8. PMID: 7923554.
      Citations: 2     Fields:    Translation:AnimalsCells
    35. Priest DG, Schmitz JC, Walle T, Priest DG, Schmitz JC, Walle T. Leucovorin as a prodrug. Adv Exp Med Biol. 1993; 339:31-40; discussion 41-2. PMID: 8178726.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    36. Priest DG, Schmitz JC, Bunni MA, Priest DG, Schmitz JC, Bunni MA. Folate metabolites as modulators of antitumor drug activity. Adv Exp Med Biol. 1993; 338:693-8. PMID: 8304208.
      Citations: 1     Fields:    Translation:HumansCells
    37. Pavlovic M, Leffert JJ, Russello O, Bunni MA, Beardsley GP, Priest DG, Pizzorno G, Pavlovic M, Leffert JJ, Russello O, Bunni MA, Beardsley GP, Priest DG, Pizzorno G. Altered transport of folic acid and antifolates through the carrier mediated reduced folate transport system in a human leukemia cell line resistant to (6R) 5,10-dideazatetrahydrofolic acid (DDATHF). Adv Exp Med Biol. 1993; 338:775-8. PMID: 8304227.
      Citations: 1     Fields:    Translation:HumansCells
    38. Priest DG, Schmitz JC, Bunni MA, Stuart RK, Priest DG, Schmitz JC, Bunni MA, Stuart RK. Pharmacokinetics of leucovorin metabolites in human plasma as a function of dose administered orally and intravenously. J Natl Cancer Inst. 1991 Dec 18; 83(24):1806-12. PMID: 1744924.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    39. Priest DG, Bunni MA, Romero-Fredes LR, Schmitz JC, Whiteley JM, Priest DG, Bunni MA, Romero-Fredes LR, Schmitz JC, Whiteley JM. A sensitive radioenzymatic assay for (S)-5-formyltetrahydrofolate. Anal Biochem. 1991 Aug 01; 196(2):284-9. PMID: 1776677.
      Citations: 1     Fields:    Translation:HumansAnimals
    40. Bunni MA, Priest DG, Bunni MA, Priest DG. Human red blood cell-mediated metabolism of leucovorin [(R,S)5-formyltetrahydrofolate]. Arch Biochem Biophys. 1991 May 01; 286(2):633-7. PMID: 1897982.
      Citations: 1     Fields:    Translation:HumansCells
    41. Romanini A, Lin JT, Niedzwiecki D, Bunni M, Priest DG, Bertino JR, Romanini A, Lin JT, Niedzwiecki D, Bunni M, Priest DG, Bertino JR. Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin. Cancer Res. 1991 Feb 01; 51(3):789-93. PMID: 1988119.
      Citations: 9     Fields:    Translation:HumansCells
    42. Balinska M, Rhee M, Whiteley JM, Priest DG, Galivan J, Balinska M, Rhee M, Whiteley JM, Priest DG, Galivan J. Inhibition of mammalian thymidylate synthase by 10-formyltetrahydropteroylpolyglutamate. Arch Biochem Biophys. 1991 Jan; 284(1):219-22. PMID: 1989499.
      Citations: 2     Fields:    Translation:AnimalsCells
    43. Galivan J, Rhee M, Priest DG, Bunni M, Freisheim JH, Whiteley JM, Galivan J, Rhee M, Priest DG, Bunni M, Freisheim JH, Whiteley JM. The effect of methotrexate on the folate coenzyme pools in human hepatoma cells in culture. Adv Exp Med Biol. 1991; 309A:75-8. PMID: 1665010.
      Citations:    Fields:    Translation:HumansCells
    44. Rhee MS, Balinska M, Bunni M, Priest DG, Maley GF, Maley F, Galivan J, Rhee MS, Balinska M, Bunni M, Priest DG, Maley GF, Maley F, Galivan J. Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells. Cancer Res. 1990 Jul 01; 50(13):3979-84. PMID: 2162250.
      Citations: 3     Fields:    Translation:Cells
    45. Priest DG, Bunni M, Sirotnak FM, Priest DG, Bunni M, Sirotnak FM. Relationship of reduced folate changes to inhibition of DNA synthesis induced by methotrexate in L1210 cells in vivo. Cancer Res. 1989 Aug 01; 49(15):4204-9. PMID: 2743307.
      Citations: 1     Fields:    Translation:Animals
    46. Galivan J, Rhee MS, Johnson TB, Dilwith R, Nair MG, Bunni M, Priest DG, Galivan J, Rhee MS, Johnson TB, Dilwith R, Nair MG, Bunni M, Priest DG. The role of cellular folates in the enhancement of activity of the thymidylate synthase inhibitor 10-propargyl-5,8-dideazafolate against hepatoma cells in vitro by inhibitors of dihydrofolate reductase. J Biol Chem. 1989 Jun 25; 264(18):10685-92. PMID: 2525127.
      Citations: 4     Fields:    Translation:AnimalsCells
    47. Rhee MS, Johnson TB, Priest DG, Galivan J, Rhee MS, Johnson TB, Priest DG, Galivan J. The effect of methionine on methotrexate metabolism in rat hepatocytes in monolayer culture. Biochim Biophys Acta. 1989 May 10; 1011(2-3):122-8. PMID: 2565736.
      Citations: 1     Fields:    Translation:AnimalsCells
    48. Galivan J, Rhee MS, Johnson TB, Chou TC, Nair MG, Bunni M, Priest D, Galivan J, Rhee MS, Johnson TB, Chou TC, Nair MG, Bunni M, Priest D. The enhancement of the activity of 10-propargyl-5,8-dideazafolate and 5,10-dideazatetrahydrofolate by inhibitors of dihydrofolate reductase. Adv Enzyme Regul. 1989; 28:13-21. PMID: 2624172.
      Citations:    Fields:    Translation:AnimalsCells
    49. Bunni MA, Rembiesa BM, Priest DG, Sahovic E, Stuart R, Bunni MA, Rembiesa BM, Priest DG, Sahovic E, Stuart R. Accumulation of tetrahydrofolates in human plasma after leucovorin administration. Cancer Chemother Pharmacol. 1989; 23(6):353-7. PMID: 2785439.
      Citations: 3     Fields:    Translation:HumansCells
    50. Bunni M, Doig MT, Donato H, Kesavan V, Priest DG, Bunni M, Doig MT, Donato H, Kesavan V, Priest DG. Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells. Cancer Res. 1988 Jun 15; 48(12):3398-404. PMID: 3370638.
      Citations: 4     Fields:    Translation:AnimalsCells
    51. Donato H, Doig MT, Priest DG, Donato H, Doig MT, Priest DG. Enhancement of polyacrylamide gel slice dissolution in hydrogen peroxide by cupric sulfate. J Biochem Biophys Methods. 1988 Apr; 15(6):331-5. PMID: 3379246.
      Citations: 1     Fields:    
    52. Galivan J, Johnson T, Rhee M, McGuire JJ, Priest D, Kesevan V, Galivan J, Johnson T, Rhee M, McGuire JJ, Priest D, Kesevan V. The role of folylpolyglutamate synthetase and gamma-glutamyl hydrolase in altering cellular folyl- and antifolylpolyglutamates. Adv Enzyme Regul. 1987; 26:147-55. PMID: 3499766.
      Citations: 1     Fields:    Translation:Animals
    53. Scanlon KJ, Newman EM, Lu Y, Priest DG, Scanlon KJ, Newman EM, Lu Y, Priest DG. Biochemical basis for cisplatin and 5-fluorouracil synergism in human ovarian carcinoma cells. Proc Natl Acad Sci U S A. 1986 Dec; 83(23):8923-5. PMID: 3466165; PMCID: PMC387045.
      Citations: 68     Fields:    Translation:HumansCells
    54. Kesavan V, Doig MT, Priest DG, Kesavan V, Doig MT, Priest DG. A radioenzymatic method for the determination of tissue 10-formyltetrahydrofolate. J Biochem Biophys Methods. 1986 Jun; 12(5-6):311-7. PMID: 3734324.
      Citations: 1     Fields:    Translation:Animals
    55. Samuels LL, Goutas LJ, Priest DG, Piper JR, Sirotnak FM, Samuels LL, Goutas LJ, Priest DG, Piper JR, Sirotnak FM. Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse. Cancer Res. 1986 May; 46(5):2230-5. PMID: 2421872.
      Citations: 3     Fields:    Translation:Animals
    56. Stratton LP, Hynes JB, Priest DG, Doig MT, Barron DA, Asleson GL, Stratton LP, Hynes JB, Priest DG, Doig MT, Barron DA, Asleson GL. Micellar high-performance liquid chromatographic determination of folylpolyglutamate hydrolase activity. J Chromatogr. 1986 Apr 23; 357(1):183-9. PMID: 3754877.
      Citations:    Fields:    Translation:Animals
    57. Sur P, Priest DG, Doig MT, Sur P, Priest DG, Doig MT. Effects of growth rate and methotrexate on folate polyglutamates and folylpolyglutamate hydrolase activity in Krebs ascites cells. Biochem Cell Biol. 1986 Apr; 64(4):363-7. PMID: 3755049.
      Citations: 1     Fields:    Translation:Animals
    58. Kesavan V, Sur P, Doig MT, Scanlon KJ, Priest DG, Kesavan V, Sur P, Doig MT, Scanlon KJ, Priest DG. Effects of methotrexate on folates in Krebs ascites and L1210 murine leukemia cells. Cancer Lett. 1986 Jan; 30(1):55-9. PMID: 3943080.
      Citations: 4     Fields:    Translation:AnimalsCells
    59. Priest DG, Doig MT, Priest DG, Doig MT. Tissue folate polyglutamate chain length determination by electrophoresis as thymidylate synthase-fluorodeoxyuridylate ternary complexes. Methods Enzymol. 1986; 122:313-9. PMID: 3517565.
      Citations: 3     Fields:    Translation:AnimalsCells
    60. Doig MT, Peters JR, Sur P, Dang M, Priest DG, Doig MT, Peters JR, Sur P, Dang M, Priest DG. Determination of mouse liver 5-methyltetrahydrofolate concentration and polyglutamate forms. J Biochem Biophys Methods. 1985 Mar; 10(5-6):287-94. PMID: 3998382.
      Citations: 1     Fields:    Translation:Animals
    61. Sur P, Doig MT, Priest DG, Sur P, Doig MT, Priest DG. Response of methylenetetrahydrofolate levels to methotrexate in Krebs ascites cells. Biochem J. 1983 Nov 15; 216(2):295-8. PMID: 6661197; PMCID: PMC1152504.
      Citations: 2     Fields:    Translation:Animals
    62. Priest DG, Doig MT, Mangum M, Priest DG, Doig MT, Mangum M. Response of mouse hepatoma cell methylenetetrahydrofolate polyglutamates to folate deprivation. Biochim Biophys Acta. 1983 Apr 20; 756(3):253-7. PMID: 6600935.
      Citations: 2     Fields:    Translation:AnimalsCells
    63. Priest DG, Doig MT, Priest DG, Doig MT. Evaluation of folylpolyglutamates by electrophoretic separation of fluorodeoxyuridylate-thymidylate synthase-methylenetetrahydrofolate complexes. Adv Exp Med Biol. 1983; 163:139-48. PMID: 6412520.
      Citations: 1     Fields:    Translation:AnimalsCells
    64. Collawn JF, Priest DG, Fish WW, Collawn JF, Priest DG, Fish WW. A sensitive assay employing a solid-phase metal chelator to estimate rates of iron accumulation by ferritin. Anal Biochem. 1982 Nov 15; 127(1):105-11. PMID: 7165079.
      Citations:    Fields:    Translation:Cells
    65. Priest DG, Veronee CD, Mangum M, Bednarek JM, Doig MT, Priest DG, Veronee CD, Mangum M, Bednarek JM, Doig MT. Comparison of folylpolyglutamate hydrolases of mouse liver, kidney, muscle and brain. Mol Cell Biochem. 1982 Mar 19; 43(2):81-7. PMID: 6178012.
      Citations: 8     Fields:    Translation:AnimalsCells
    66. Priest DG, Doig MT, Ledford BE, Priest DG, Doig MT, Ledford BE. Cell cycle patterns of thymidylate synthetase and 5,10-methylenetetrahydrofolate polyglutamates in cultured mouse hepatoma cells. Experientia. 1982 Jan 15; 38(1):88-9. PMID: 7056367.
      Citations: 1     Fields:    Translation:AnimalsCells
    67. Priest DG, Doig MT, Bednarek JM, McGuire JJ, Bertino JR, Priest DG, Doig MT, Bednarek JM, McGuire JJ, Bertino JR. Electrophoretic assay of folylpolyglutamate synthetase activity. J Biochem Biophys Methods. 1981 Dec; 5(5):273-7. PMID: 6895904.
      Citations:    Fields:    
    68. Priest DG, Mangum M, Priest DG, Mangum M. Relative affinity of 5,10-methylenetetrahydrofolylpolyglutamates for the Lactobacillus casei thymidylate synthetase-5-fluorodeoxyuridylate binary complex. Arch Biochem Biophys. 1981 Aug; 210(1):118-23. PMID: 6170260.
      Citations:    Fields:    Translation:Cells
    69. Priest DG, Happel KK, Mangum M, Bednarek JM, Doig MT, Baugh CM, Priest DG, Happel KK, Mangum M, Bednarek JM, Doig MT, Baugh CM. Tissue folylpolyglutamate chain-length characterization by electrophoresis as thymidylate synthetase-fluorodeoxyuridylate ternary complexes. Anal Biochem. 1981 Jul 15; 115(1):163-9. PMID: 6795960.
      Citations: 2     Fields:    Translation:AnimalsCells
    70. Priest DG, Doig MT, Hynes JB, Priest DG, Doig MT, Hynes JB. Purification of mouse liver thymidylate synthetase by affinity chromatography using 10-methyl-5,8-dideazafolate as the affinant. Experientia. 1981 Feb 15; 37(2):119-20. PMID: 7238733.
      Citations: 2     Fields:    Translation:Animals
    71. Priest DG, Happel KK, Doig MT, Priest DG, Happel KK, Doig MT. Electrophoretic identification of poly-gamma-glutamate chain-lengths of 5,10-methylenetetrahydrofolate using thymidylate synthetase complexes. J Biochem Biophys Methods. 1980 Oct; 3(4):201-6. PMID: 7451813.
      Citations: 3     Fields:    
    72. Priest DG, Ledford BE, Doig MT, Priest DG, Ledford BE, Doig MT. Increased thymidylate synthetase in 5-fluorodeoxyuridine resistant cultured hepatoma cells. Biochem Pharmacol. 1980 Jun 01; 29(11):1549-53. PMID: 6446915.
      Citations: 12     Fields:    Translation:AnimalsCells
    73. Conley TG, Priest DG, Conley TG, Priest DG. Thermodynamics and stoicheiometry of the binding of substrate analogues to uricase. Biochem J. 1980 Jun 01; 187(3):727-32. PMID: 6821367; PMCID: PMC1162457.
      Citations: 5     Fields:    Translation:Animals
    74. Conley TG, Priest DG, Conley TG, Priest DG. Non-classical inhibition of uricase by cyanide. Biochem J. 1980 Jun 01; 187(3):733-8. PMID: 6821368; PMCID: PMC1162458.
      Citations: 2     Fields:    Translation:AnimalsCells
    75. Priest DG, Alford CW, Batson KK, Doig MT, Priest DG, Alford CW, Batson KK, Doig MT. A centrifugal column assay for thymidylate synthetase using the active site titrant 5-fluoro-2'-deoxyuridylate. Anal Biochem. 1980 Mar 15; 103(1):51-4. PMID: 7377545.
      Citations: 5     Fields:    Translation:AnimalsCells
    76. Pitts OM, Priest DG, Pitts OM, Priest DG. A steady-state kinetic investigation of the uricase reaction mechanism. Arch Biochem Biophys. 1974 Jul; 163(1):359-66. PMID: 4850315.
      Citations: 3     Fields:    Translation:AnimalsCells
    77. Orr RK, Hoehn JL, Col NF, Priest DG, Pitts OM. Reaction intermediate effects on the spectrophotometric uricase assay. Anal Biochem. 1972 Nov; 50(1):195-205. PMID: 5080726.
      Citations: 5     Fields:    
    78. Priest DG, Fisher JR, Priest DG, Fisher JR. Nonlinear kinetics of the xanthine oxidase reaction catalyzed by chicken liver xanthine dehydrogenase. Arch Biochem Biophys. 1971 Oct; 146(2):391-9. PMID: 5165517.
      Citations: 1     Fields:    Translation:AnimalsCells
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