"Cathelicidins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a more variable carboxy terminal domain. They are initially synthesized as preproproteins and then cleaved. They are expressed in many tissues of humans and localized to EPITHELIAL CELLS. They kill nonviral pathogens by forming pores in membranes.
| Descriptor ID |
D054804
|
| MeSH Number(s) |
D12.644.050.099 D12.776.543.695.054.099
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cathelicidins".
Below are MeSH descriptors whose meaning is more specific than "Cathelicidins".
This graph shows the total number of publications written about "Cathelicidins" by people in this website by year, and whether "Cathelicidins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 3 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathelicidins" by people in Profiles.
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Francisella novicida Two-Component System Response Regulator BfpR Modulates iglC Gene Expression, Antimicrobial Peptide Resistance, and Biofilm Production. Front Cell Infect Microbiol. 2020; 10:82.
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Circulating Cathelicidin Concentrations in a Cohort of Healthy Children: Influence of Age, Body Composition, Gender and Vitamin D Status. PLoS One. 2016; 11(5):e0152711.
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LL-37 concentrations and the relationship to vitamin D, immune status, and inflammation in HIV-infected children and young adults. AIDS Res Hum Retroviruses. 2014 Jul; 30(7):670-6.
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Suppression of iron-regulatory hepcidin by vitamin D. J Am Soc Nephrol. 2014 Mar; 25(3):564-72.
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Antibacterial mesh: a novel technique involving naturally occurring cellular proteins. Surg Innov. 2012 Mar; 19(1):20-6.
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Cholesterol enhances Helicobacter pylori resistance to antibiotics and LL-37. Antimicrob Agents Chemother. 2011 Jun; 55(6):2897-904.
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Vitamin D-mediated induction of innate immunity in gingival epithelial cells. Infect Immun. 2011 Jun; 79(6):2250-6.
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Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses. PLoS One. 2009 Jun 05; 4(6):e5810.
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Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science. 2006 Mar 24; 311(5768):1770-3.