"Glycosyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the transfer of glycosyl groups to an acceptor. Most often another carbohydrate molecule acts as an acceptor, but inorganic phosphate can also act as an acceptor, such as in the case of PHOSPHORYLASES. Some of the enzymes in this group also catalyze hydrolysis, which can be regarded as transfer of a glycosyl group from the donor to water. Subclasses include the HEXOSYLTRANSFERASES; PENTOSYLTRANSFERASES; SIALYLTRANSFERASES; and those transferring other glycosyl groups. EC 2.4.
Descriptor ID |
D016695
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MeSH Number(s) |
D08.811.913.400
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycosyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Glycosyltransferases".
This graph shows the total number of publications written about "Glycosyltransferases" by people in this website by year, and whether "Glycosyltransferases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
1995 | 1 | 0 | 1 |
1996 | 1 | 0 | 1 |
1997 | 1 | 0 | 1 |
1998 | 1 | 0 | 1 |
2000 | 1 | 0 | 1 |
2003 | 1 | 0 | 1 |
2006 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glycosyltransferases" by people in Profiles.
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Powell AJ, Liu ZJ, Nicholas RA, Davies C. Crystal structures of the lytic transglycosylase MltA from N.gonorrhoeae and E.coli: insights into interdomain movements and substrate binding. J Mol Biol. 2006 May 26; 359(1):122-36.
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Loutre C, Dixon DP, Brazier M, Slater M, Cole DJ, Edwards R. Isolation of a glucosyltransferase from Arabidopsis thaliana active in the metabolism of the persistent pollutant 3,4-dichloroaniline. Plant J. 2003 May; 34(4):485-93.
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Toole BP. Hyaluronan is not just a goo! J Clin Invest. 2000 Aug; 106(3):335-6.
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DeAngelis PL, Jing W, Drake RR, Achyuthan AM. Identification and molecular cloning of a unique hyaluronan synthase from Pasteurella multocida. J Biol Chem. 1998 Apr 03; 273(14):8454-8.
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Sugumaran G, Katsman M, Sunthankar P, Drake RR. Biosynthesis of chondroitin sulfate. Purification of glucuronosyl transferase II and use of photoaffinity labeling for characterization of the enzyme as an 80-kDa protein. J Biol Chem. 1997 May 30; 272(22):14399-403.
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Zeng Y, Shabalin Y, Szumilo T, Pastuszak I, Drake RR, Elbein AD. Synthesis of aryl azide derivatives of UDP-GlcNAc and UDP-GalNAc and their use for the affinity labeling of glycosyltransferases and the UDP-HexNAc pyrophosphorylase. Anal Biochem. 1996 Jul 15; 239(1):99-106.
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Little JM, Drake RR, Vonk R, Kuipers F, Lester R, Radominska A. Characterization of human liver microsomal UDP-glycosyltransferases using photoaffinity analogs. J Pharmacol Exp Ther. 1995 Jun; 273(3):1551-9.
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Radominska A, Drake RR. Synthesis and uses of azido-substituted nucleoside diphosphate sugar photoaffinity analogs. Methods Enzymol. 1994; 230:330-9.
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van de Rijn I, Drake RR. Analysis of the streptococcal hyaluronic acid synthase complex using the photoaffinity probe 5-azido-UDP-glucuronic acid. J Biol Chem. 1992 Dec 05; 267(34):24302-6.
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Drake RR, Elbein AD. Photoaffinity labelling of glycosyltransferases. Glycobiology. 1992 Aug; 2(4):279-84.