Alkyl and Aryl Transferases
"Alkyl and Aryl Transferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A somewhat heterogeneous class of enzymes that catalyze the transfer of alkyl or related groups (excluding methyl groups). EC 2.5.
| Descriptor ID |
D019883
|
| MeSH Number(s) |
D08.811.913.225
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Alkyl and Aryl Transferases".
Below are MeSH descriptors whose meaning is more specific than "Alkyl and Aryl Transferases".
This graph shows the total number of publications written about "Alkyl and Aryl Transferases" by people in this website by year, and whether "Alkyl and Aryl Transferases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2006 | 1 | 2 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alkyl and Aryl Transferases" by people in Profiles.
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Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation. Neuroscience. 2012 Jan 27; 202:1-9.
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Discovery of geranylgeranyltransferase-I inhibitors with novel scaffolds by the means of quantitative structure-activity relationship modeling, virtual screening, and experimental validation. J Med Chem. 2009 Jul 23; 52(14):4210-20.
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Effects of pharmacologic inhibition of protein geranylgeranyltransferase type I on aqueous humor outflow through the trabecular meshwork. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2464-71.
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Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors. Biochemistry. 2006 Dec 26; 45(51):15862-72.
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Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease. Biochem Biophys Res Commun. 2006 Apr 28; 343(1):229-38.
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A novel protein geranylgeranyltransferase-I inhibitor with high potency, selectivity, and cellular activity. J Biol Chem. 2006 May 05; 281(18):12445-50.
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Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. J Biol Chem. 1998 Jan 30; 273(5):2591-600.
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Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest. 1997 Dec 01; 100(11):2671-9.