"Replication Origin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A unique DNA sequence of a replicon at which DNA REPLICATION is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
- Replication Origin
- Origin, Replication
- Origins, Replication
- ori Region
- Region, ori
- Regions, ori
- ori Regions
- Origin of Replication
- Replication Origins
Below are MeSH descriptors whose meaning is more general than "Replication Origin".
Below are MeSH descriptors whose meaning is more specific than "Replication Origin".
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Below are the most recent publications written about "Replication Origin" by people in Profiles.
Rutledge MT, Russo M, Belton JM, Dekker J, Broach JR. The yeast genome undergoes significant topological reorganization in quiescence. Nucleic Acids Res. 2015 Sep 30; 43(17):8299-313.
Saxena M, Singh S, Zzaman S, Bastia D. Investigations of pi initiator protein-mediated interaction between replication origins alpha and gamma of the plasmid R6K. J Biol Chem. 2010 Feb 19; 285(8):5695-704.
Saxena M, Abhyankar M, Bastia D. Replication initiation at a distance: determination of the cis- and trans-acting elements of replication origin alpha of plasmid R6K. J Biol Chem. 2010 Feb 19; 285(8):5705-12.
Long DT, Kreuzer KN. Regression supports two mechanisms of fork processing in phage T4. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):6852-7.
Zzaman S, Bastia D. Oligomeric initiator protein-mediated DNA looping negatively regulates plasmid replication in vitro by preventing origin melting. Mol Cell. 2005 Dec 22; 20(6):833-43.
Zzaman S, Abhyankar MM, Bastia D. Reconstitution of F factor DNA replication in vitro with purified proteins. J Biol Chem. 2004 Apr 23; 279(17):17404-10.
Sharma R, Kachroo A, Bastia D. Mechanistic aspects of DnaA-RepA interaction as revealed by yeast forward and reverse two-hybrid analysis. EMBO J. 2001 Aug 15; 20(16):4577-87.
Mohanty BK, Bussiere DE, Sahoo T, Pai KS, Meijer WJ, Bron S, Bastia D. Structural and functional analysis of a bipolar replication terminus. Implications for the origin of polarity of fork arrest. J Biol Chem. 2001 Apr 20; 276(16):13160-8.
Mohanty BK, Sahoo T, Bastia D. The relationship between sequence-specific termination of DNA replication and transcription. EMBO J. 1996 May 15; 15(10):2530-9.