"Polyubiquitin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An oligomer formed from the repetitive linking of the C-terminal glycine of one UBIQUITIN molecule via an isopeptide bond to a lysine residue on a second ubiquitin molecule. It is structurally distinct from UBIQUITIN C, which is a single protein containing a tandemly arrayed ubiquitin peptide sequence.
Descriptor ID |
D025821
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MeSH Number(s) |
D12.776.947.500.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Polyubiquitin".
Below are MeSH descriptors whose meaning is more specific than "Polyubiquitin".
This graph shows the total number of publications written about "Polyubiquitin" by people in this website by year, and whether "Polyubiquitin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polyubiquitin" by people in Profiles.
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K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair. Sci Signal. 2018 06 05; 11(533).
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TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017 05 18; 545(7654):365-369.
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A mutually assured destruction mechanism attenuates light signaling in Arabidopsis. Science. 2014 Jun 06; 344(6188):1160-1164.