"Ubiquitination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The act of ligating UBIQUITINS to PROTEINS to form ubiquitin-protein ligase complexes to label proteins for transport to the PROTEASOME ENDOPEPTIDASE COMPLEX where proteolysis occurs.
| Descriptor ID |
D054875
|
| MeSH Number(s) |
G02.111.660.871.790.600.925 G02.111.691.600.775 G03.734.871.790.600.831 G05.308.670.600.831
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ubiquitination".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitination".
This graph shows the total number of publications written about "Ubiquitination" by people in this website by year, and whether "Ubiquitination" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 3 | 3 |
| 2009 | 1 | 5 | 6 |
| 2010 | 0 | 3 | 3 |
| 2011 | 1 | 5 | 6 |
| 2012 | 0 | 3 | 3 |
| 2013 | 2 | 5 | 7 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 5 | 6 |
| 2016 | 1 | 3 | 4 |
| 2017 | 1 | 4 | 5 |
| 2018 | 1 | 5 | 6 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ubiquitination" by people in Profiles.
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Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation. Nat Commun. 2022 11 03; 13(1):6614.
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Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity. Nat Commun. 2021 11 25; 12(1):6896.
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Crystal structures of an E1-E2-ubiquitin thioester mimetic reveal molecular mechanisms of transthioesterification. Nat Commun. 2021 04 22; 12(1):2370.
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The long and winding road to target protein misfolding in cardiovascular diseases. Eur J Clin Invest. 2021 May; 51(5):e13504.
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Caveolin-1 stabilizes ATP7A, a copper transporter for extracellular SOD, in vascular tissue to maintain endothelial function. Am J Physiol Cell Physiol. 2020 11 01; 319(5):C933-C944.
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CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes. J Mol Cell Cardiol. 2020 08; 145:59-73.
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Proteasome inhibition suppress microgravity elevated RANK signaling during osteoclast differentiation. Cytokine. 2020 01; 125:154821.
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Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Mol Cell. 2019 06 20; 74(6):1264-1277.e7.
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Conformational Dynamics of the HIV-Vif Protein Complex. Biophys J. 2019 04 23; 116(8):1432-1445.
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SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Dev Cell. 2019 02 11; 48(3):329-344.e5.