"DNA Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Poly(deoxyribonucleotide):poly(deoxyribonucleotide)ligases. Enzymes that catalyze the joining of preformed deoxyribonucleotides in phosphodiester linkage during genetic processes during repair of a single-stranded break in duplex DNA. The class includes both EC 6.5.1.1 (ATP) and EC 6.5.1.2 (NAD).
| Descriptor ID |
D011088
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| MeSH Number(s) |
D08.811.074.500 D08.811.464.754.600
|
| Concept/Terms |
DNA Ligases- DNA Ligases
- Ligases, DNA
- Polydeoxyribonucleotide Ligases
- Ligases, Polydeoxyribonucleotide
- Polydeoxyribonucleotide Synthetases
- Synthetases, Polydeoxyribonucleotide
- DNA Joinases
- Joinases, DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA Ligases".
Below are MeSH descriptors whose meaning is more specific than "DNA Ligases".
This graph shows the total number of publications written about "DNA Ligases" by people in this website by year, and whether "DNA Ligases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
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Below are the most recent publications written about "DNA Ligases" by people in Profiles.
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Akt promotes tumorigenesis in part through modulating genomic instability via phosphorylating XLF. Nucleus. 2015; 6(4):261-5.
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Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair. Mol Cell. 2015 Feb 19; 57(4):648-661.
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Effects of deletion and site-directed mutations on ligation steps of NAD+-dependent DNA ligase: a biochemical analysis of BRCA1 C-terminal domain. Biochemistry. 2004 Oct 05; 43(39):12648-59.
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Vaccinia DNA ligase complements Saccharomyces cerevisiae cdc9, localizes in cytoplasmic factories and affects virulence and virus sensitivity to DNA damaging agents. EMBO J. 1991 Dec; 10(13):4343-50.
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Enhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein. Cell. 1988 Feb 12; 52(3):375-83.
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Inducible repair of thymine ring saturation damage in phi X174 DNA. Radiat Res. 1983 Mar; 93(3):609-12.