Heme Oxygenase-1

"Heme Oxygenase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A ubiquitous stress-responsive enzyme that catalyzes the oxidative cleavage of HEME to yield IRON; CARBON MONOXIDE; and BILIVERDIN.

Descriptor ID	D051547
MeSH Number(s)	D08.811.682.690.708.410.500
Concept/Terms	Heme Oxygenase-1 Heme Oxygenase-1 Heme Oxygenase 1 Oxygenase-1, Heme Hemeoxygenase 1

Below are MeSH descriptors whose meaning is more general than "Heme Oxygenase-1".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Oxidoreductases [D08.811.682]
Oxygenases [D08.811.682.690]
Mixed Function Oxygenases [D08.811.682.690.708]
Heme Oxygenase (Decyclizing) [D08.811.682.690.708.410]
Heme Oxygenase-1 [D08.811.682.690.708.410.500]

Below are MeSH descriptors whose meaning is related to "Heme Oxygenase-1".

Below are MeSH descriptors whose meaning is more specific than "Heme Oxygenase-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Heme Oxygenase-1" by people in this website by year, and whether "Heme Oxygenase-1" was a major or minor topic of these publications.

Bar chart showing 25 publications over 19 distinct years, with a maximum of 3 publications in 2014 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2003	0	1	1
2004	0	1	1
2005	0	1	1
2006	0	2	2
2007	0	1	1
2008	0	1	1
2009	0	1	1
2010	1	0	1
2011	1	0	1
2013	0	1	1
2014	2	1	3
2016	1	0	1
2017	0	1	1
2018	0	1	1
2019	2	1	3
2020	0	1	1
2021	1	0	1
2022	1	1	2

Below are the most recent publications written about "Heme Oxygenase-1" by people in Profiles.

Cai L, Arbab AS, Lee TJ, Sharma A, Thomas B, Igarashi K, Raju RP. BACH1-Hemoxygenase-1 axis regulates cellular energetics and survival following sepsis. Free Radic Biol Med. 2022 08 01; 188:134-145.

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Fernández-Morales JC, Morad M. Oxygen sensor of the heart. Can J Physiol Pharmacol. 2022 Sep 01; 100(9):848-857.

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Zhu H, Klement JD, Lu C, Redd PS, Yang D, Smith AD, Poschel DB, Zou J, Liu D, Wang PG, Ostrov D, Coant N, Hannun YA, Colby AH, Grinstaff MW, Liu K. Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis. J Immunol. 2021 03 15; 206(6):1395-1404.

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Fernandez K, Spielbauer KK, Rusheen A, Wang L, Baker TG, Eyles S, Cunningham LL. Lovastatin protects against cisplatin-induced hearing loss in mice. Hear Res. 2020 04; 389:107905.

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Zhang L, Zhang J, Ye Z, Manevich Y, Ball LE, Bethard JR, Jiang YL, Broome AM, Dalton AC, Wang GY, Townsend DM, Tew KD. Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1. Cancer Res. 2019 08 15; 79(16):4072-4085.

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El-Achkar GA, Mrad MF, Mouawad CA, Badran B, Jaffa AA, Motterlini R, Hamade E, Habib A. Heme oxygenase-1-Dependent anti-inflammatory effects of atorvastatin in zymosan-injected subcutaneous air pouch in mice. PLoS One. 2019; 14(5):e0216405.

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Fix C, Carver-Molina A, Chakrabarti M, Azhar M, Carver W. Effects of the isothiocyanate sulforaphane on TGF-ß1-induced rat cardiac fibroblast activation and extracellular matrix interactions. J Cell Physiol. 2019 08; 234(8):13931-13941.

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Khan M, Shunmugavel A, Dhammu TS, Khan H, Singh I, Singh AK. Combined treatment with GSNO and CAPE accelerates functional recovery via additive antioxidant activities in a mouse model of TBI. J Neurosci Res. 2018 12; 96(12):1900-1913.

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Davis C, Dukes A, Drewry M, Helwa I, Johnson MH, Isales CM, Hill WD, Liu Y, Shi X, Fulzele S, Hamrick MW. MicroRNA-183-5p Increases with Age in Bone-Derived Extracellular Vesicles, Suppresses Bone Marrow Stromal (Stem) Cell Proliferation, and Induces Stem Cell Senescence. Tissue Eng Part A. 2017 11; 23(21-22):1231-1240.

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Dai L, Qiao J, Nguyen D, Struckhoff AP, Doyle L, Bonstaff K, Del Valle L, Parsons C, Toole BP, Renne R, Qin Z. Role of heme oxygenase-1 in the pathogenesis and tumorigenicity of Kaposi's sarcoma-associated herpesvirus. Oncotarget. 2016 Mar 01; 7(9):10459-71.

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