Peptide Elongation Factor 2
"Peptide Elongation Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide Elongation Factor 2 catalyzes the translocation of peptidyl-tRNA from the A site to the P site of eukaryotic ribosomes by a process linked to the hydrolysis of GTP to GDP.
| Descriptor ID |
D020652
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| MeSH Number(s) |
D08.811.277.040.330.300.100.102 D12.776.157.325.150.102 D12.776.835.700.350.102
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peptide Elongation Factor 2".
Below are MeSH descriptors whose meaning is more specific than "Peptide Elongation Factor 2".
This graph shows the total number of publications written about "Peptide Elongation Factor 2" by people in this website by year, and whether "Peptide Elongation Factor 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peptide Elongation Factor 2" by people in Profiles.
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Remodeling Translation Primes CD8+ T-cell Antitumor Immunity. Cancer Immunol Res. 2020 05; 8(5):587-595.
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The role of protein synthesis in cell cycling and cancer. Mol Oncol. 2009 Dec; 3(5-6):402-8.
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Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy. Mol Endocrinol. 2008 Nov; 22(11):2531-43.
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Hypoxic reactive oxygen species regulate the integrated stress response and cell survival. J Biol Chem. 2008 Nov 07; 283(45):31153-62.
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Doxorubicin generates a proapoptotic phenotype by phosphorylation of elongation factor 2. Free Radic Biol Med. 2007 Nov 01; 43(9):1313-21.
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Chlorolissoclimides: new inhibitors of eukaryotic protein synthesis. RNA. 2006 May; 12(5):717-25.
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Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem. 2003 Oct 24; 278(43):42041-9.