"Cyclosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
| Descriptor ID |
D003524
|
| MeSH Number(s) |
D04.345.566.235 D12.644.641.235
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclosporins".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporins".
This graph shows the total number of publications written about "Cyclosporins" by people in this website by year, and whether "Cyclosporins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclosporins" by people in Profiles.
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Pacchioni AM, Gabriele A, Donovan JL, DeVane CL, See RE. P-glycoprotein inhibition potentiates the behavioural and neurochemical actions of risperidone in rats. Int J Neuropsychopharmacol. 2010 Sep; 13(8):1067-77.
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Watanabe T, Uchiyama N, Roninson IB, Cohen D, Atadja P. Altered activity of MDR-reversing agents on KB3-1 cells transfected with Gly(185)-->Val human P-glycoprotein. Int J Oncol. 2000 Sep; 17(3):579-86.
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Stevens SL, Tyler JD, Freeman MB, Hopkins F, Lewis T, Bray J, Edwards AL, Brockbank K, Goldman MH. Factors affecting patency of venous allografts in miniature swine. J Vasc Surg. 1990 Sep; 12(3):361-6.
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Cotton P. New approaches may aid patients with inflammatory bowel disease. JAMA. 1990 Jun 20; 263(23):3121-2.
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Garin EH, Orak JK, Hiott KL, Sutherland SE. Cyclosporine therapy for steroid-resistant nephrotic syndrome. A controlled study. Am J Dis Child. 1988 Sep; 142(9):985-8.
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Canafax DM, Cipolle RJ, Hrushesky WJ, Rabatin JT, Min DI, Graves NM, Sutherland DE, Bowers LD. The chronopharmacokinetics of cyclosporine and its metabolites in recipients of pancreas allografts. Transplant Proc. 1988 Apr; 20(2 Suppl 2):471-7.
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Cipolle RJ, Canafax DM, Rabatin J, Bowers LD, Sutherland DE, Hrushesky WJ. Time-dependent disposition of cyclosporine after pancreas transplantation, and application of chronopharmacokinetics to improve immunosuppression. Pharmacotherapy. 1988; 8(1):47-51.
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Hrushesky WJ. Distinguishing between renal allograft rejection and cyclosporin nephrotoxicity. Lancet. 1985 Aug 31; 2(8453):501.
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Hrushesky WJ. Cyclosporine timing and kidney damage. N Engl J Med. 1985 Jul 18; 313(3):184.
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Magnus G, Cavallini M, Halberg F, Cornelissen G, Sutherland DE, Najarian JA, Hrushesky WJ. Circadian toxicology of cyclosporin. Toxicol Appl Pharmacol. 1985 Jan; 77(1):181-5.