"Opsins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Photosensitive proteins in the membranes of PHOTORECEPTOR CELLS such as the rods and the cones. Opsins have varied light absorption properties and are members of the G-PROTEIN-COUPLED RECEPTORS family. Their ligands are VITAMIN A-based chromophores.
| Descriptor ID |
D055355
|
| MeSH Number(s) |
D12.776.306.466 D23.767.930.750
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Opsins".
Below are MeSH descriptors whose meaning is more specific than "Opsins".
This graph shows the total number of publications written about "Opsins" by people in this website by year, and whether "Opsins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 2 | 3 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Opsins" by people in Profiles.
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Luo DG, Silverman D, Frederiksen R, Adhikari R, Cao LH, Oatis JE, Kono M, Cornwall MC, Yau KW. Apo-Opsin and Its Dark Constitutive Activity across Retinal Cone Subtypes. Curr Biol. 2020 12 21; 30(24):4921-4931.e5.
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Hanneken A, Neikirk T, Johnson J, Kono M. Biochemical Measurements of Free Opsin in Macular Degeneration Eyes: Examining the 11-CIS Retinal Deficiency Hypothesis of Delayed Dark Adaptation (An American Ophthalmological Society Thesis). Trans Am Ophthalmol Soc. 2017 Aug; 115:T1.
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Kono M. Cone Health and Retinoids. Prog Mol Biol Transl Sci. 2015; 134:465-76.
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Isayama T, Chen Y, Kono M, Fabre E, Slavsky M, DeGrip WJ, Ma JX, Crouch RK, Makino CL. Coexpression of three opsins in cone photoreceptors of the salamander Ambystoma tigrinum. J Comp Neurol. 2014 Jul 01; 522(10):2249-65.
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Stefanik MT, Kupchik YM, Brown RM, Kalivas PW. Optogenetic evidence that pallidal projections, not nigral projections, from the nucleus accumbens core are necessary for reinstating cocaine seeking. J Neurosci. 2013 Aug 21; 33(34):13654-62.
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Fan J, Crouch RK, Kono M. Light prevents exogenous 11-cis retinal from maintaining cone photoreceptors in chromophore-deficient mice. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2412-6.
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Kolesnikov AV, Fan J, Crouch RK, Kefalov VJ. Age-related deterioration of rod vision in mice. J Neurosci. 2010 Aug 18; 30(33):11222-31.
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Fan J, Sakurai K, Chen CK, Rohrer B, Wu BX, Yau KW, Kefalov V, Crouch RK. Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism. J Neurosci. 2010 Feb 17; 30(7):2496-503.
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Kono M. Assays for inverse agonists in the visual system. Methods Enzymol. 2010; 485:213-24.
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Estevez ME, Kolesnikov AV, Ala-Laurila P, Crouch RK, Govardovskii VI, Cornwall MC. The 9-methyl group of retinal is essential for rapid Meta II decay and phototransduction quenching in red cones. J Gen Physiol. 2009 Aug; 134(2):137-50.