2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
"2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective D1 dopamine receptor agonist used primarily as a research tool.
| Descriptor ID |
D015647
|
| MeSH Number(s) |
D03.633.100.079.800
|
| Concept/Terms |
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine- 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine
- 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-
SK&F-38393- SK&F-38393
- SK&F 38393
- SK&F38393
- SKF38393
- SKF-38393
- SKF 38393
- R-SK&F 38393
- RSK&F 38393
- SKF 38393-A
- SKF 38393 A
- SKF 38393A
|
Below are MeSH descriptors whose meaning is more general than "2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine".
Below are MeSH descriptors whose meaning is more specific than "2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine".
This graph shows the total number of publications written about "2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine" by people in this website by year, and whether "2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine" by people in Profiles.
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Ethanol facilitates glutamatergic transmission to dopamine neurons in the ventral tegmental area. Neuropsychopharmacology. 2009 Jan; 34(2):307-18.
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Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner. Neuroscience. 2001; 104(2):335-46.
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Dopamine modulates the responsivity of mediodorsal thalamic cells recorded in vitro. J Neurosci. 1998 Dec 15; 18(24):10566-78.
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DAD1- and DAD2-like agonist effects on motor activity of C57 mice: differences compared to rats. Synapse. 1997 May; 26(1):81-92.
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Repeated intra-ventral tegmental area administration of SKF-38393 induces behavioral and neurochemical sensitization to a subsequent cocaine challenge. J Pharmacol Exp Ther. 1996 Jul; 278(1):384-92.
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Amphetamine produces sensitized increases in locomotion and extracellular dopamine preferentially in the nucleus accumbens shell of rats administered repeated cocaine. J Pharmacol Exp Ther. 1995 Nov; 275(2):1019-29.
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Individual differences in behavior following amphetamine, GBR-12909, or apomorphine but not SKF-38393 or quinpirole. Psychopharmacology (Berl). 1994 Oct; 116(2):217-25.
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In vivo assessment of release and metabolism of dopamine in the ventrolateral striatum of awake rats following administration of dopamine D1 and D2 receptor agonists and antagonists. Neuropharmacology. 1991 Dec; 30(12A):1269-74.
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Differential modulation of striatonigral dynorphin and enkephalin by dopamine receptor subtypes. Brain Res. 1990 Jan 15; 507(1):57-64.
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Effects of dopamine D1 and D2 receptor antagonists on oral activity in rats. Pharmacol Biochem Behav. 1989 Sep; 34(1):43-8.