"Microfibrils" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Components of the extracellular matrix consisting primarily of fibrillin. They are essential for the integrity of elastic fibers.
Descriptor ID |
D020894
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MeSH Number(s) |
A11.284.295.310.560
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microfibrils".
Below are MeSH descriptors whose meaning is more specific than "Microfibrils".
This graph shows the total number of publications written about "Microfibrils" by people in this website by year, and whether "Microfibrils" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microfibrils" by people in Profiles.
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Loeys BL, Gerber EE, Riegert-Johnson D, Iqbal S, Whiteman P, McConnell V, Chillakuri CR, Macaya D, Coucke PJ, De Paepe A, Judge DP, Wigley F, Davis EC, Mardon HJ, Handford P, Keene DR, Sakai LY, Dietz HC. Mutations in fibrillin-1 cause congenital scleroderma: stiff skin syndrome. Sci Transl Med. 2010 Mar 17; 2(23):23ra20.
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Rentz TJ, Poobalarahi F, Bornstein P, Sage EH, Bradshaw AD. SPARC regulates processing of procollagen I and collagen fibrillogenesis in dermal fibroblasts. J Biol Chem. 2007 Jul 27; 282(30):22062-71.
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Judge DP, Biery NJ, Keene DR, Geubtner J, Myers L, Huso DL, Sakai LY, Dietz HC. Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome. J Clin Invest. 2004 Jul; 114(2):172-81.