"CD11c Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.
- CD11c Antigen
- Antigen, CD11c
- Antigens, CD11c
- CD11c Antigens
- Integrin alphaX
- alphaX, Integrin
- Leu-M5 Antigens
- Antigens, Leu-M5
- Leu M5 Antigens
Below are MeSH descriptors whose meaning is more general than "CD11c Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD11c Antigen".
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Below are the most recent publications written about "CD11c Antigen" by people in Profiles.
Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus. Immunology. 2022 11; 167(3):354-367.
Gut homeostasis and regulatory T cell induction depend on molecular chaperone gp96 in CD11c+ cells. Sci Rep. 2017 05 19; 7(1):2171.
miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses. Immunology. 2014 Nov; 143(3):478-89.
Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells. J Immunol. 2014 Jun 15; 192(12):5679-86.
NK depletion results in increased CCL22 secretion and Treg levels in Lewis lung carcinoma via the accumulation of CCL22-secreting CD11b+CD11c+ cells. Int J Cancer. 2010 Dec 01; 127(11):2598-611.
Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity. Diabetes. 2010 Jul; 59(7):1648-56.
GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis. Int Immunol. 2009 Mar; 21(3):269-82.