"CD11c Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit of approximately 150-kDa molecular weight. It is expressed at high levels on monocytes and combines with CD18 ANTIGEN to form the cell surface receptor INTEGRIN ALPHAXBETA2. The subunit contains a conserved I-domain which is characteristic of several of alpha integrins.
| Descriptor ID |
D039521
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| MeSH Number(s) |
D12.776.395.550.200.074.875 D12.776.395.550.200.275.500 D12.776.543.550.200.093.875 D12.776.543.550.200.275.500 D12.776.543.750.705.408.100.200 D12.776.543.750.705.408.600.100.500 D12.776.543.750.705.833.249.500 D23.050.301.350.074.074 D23.050.301.350.275.500
|
| Concept/Terms |
CD11c Antigen- CD11c Antigen
- Antigen, CD11c
- Antigens, CD11c
- CD11c Antigens
- Integrin alphaX
- alphaX, Integrin
- Leu-M5 Antigens
- Antigens, Leu-M5
- Leu M5 Antigens
|
Below are MeSH descriptors whose meaning is more general than "CD11c Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD11c Antigen".
This graph shows the total number of publications written about "CD11c Antigen" by people in this website by year, and whether "CD11c Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD11c Antigen" by people in Profiles.
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Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus. Immunology. 2022 11; 167(3):354-367.
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Gut homeostasis and regulatory T cell induction depend on molecular chaperone gp96 in CD11c+ cells. Sci Rep. 2017 05 19; 7(1):2171.
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miR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses. Immunology. 2014 Nov; 143(3):478-89.
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Deletion of CD24 impairs development of heat shock protein gp96-driven autoimmune disease through expansion of myeloid-derived suppressor cells. J Immunol. 2014 Jun 15; 192(12):5679-86.
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NK depletion results in increased CCL22 secretion and Treg levels in Lewis lung carcinoma via the accumulation of CCL22-secreting CD11b+CD11c+ cells. Int J Cancer. 2010 Dec 01; 127(11):2598-611.
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Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity. Diabetes. 2010 Jul; 59(7):1648-56.
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GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis. Int Immunol. 2009 Mar; 21(3):269-82.