Bronchial Hyperreactivity
"Bronchial Hyperreactivity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Descriptor ID |
D016535
|
| MeSH Number(s) |
C08.127.210
|
| Concept/Terms |
Bronchial Hyperreactivity- Bronchial Hyperreactivity
- Bronchial Hyperreactivities
- Hyperreactivities, Bronchial
- Hyperreactivity, Bronchial
|
Below are MeSH descriptors whose meaning is more general than "Bronchial Hyperreactivity".
Below are MeSH descriptors whose meaning is more specific than "Bronchial Hyperreactivity".
This graph shows the total number of publications written about "Bronchial Hyperreactivity" by people in this website by year, and whether "Bronchial Hyperreactivity" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bronchial Hyperreactivity" by people in Profiles.
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Price MM, Oskeritzian CA, Falanga YT, Harikumar KB, Allegood JC, Alvarez SE, Conrad D, Ryan JJ, Milstien S, Spiegel S. A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma. J Allergy Clin Immunol. 2013 Feb; 131(2):501-11.e1.
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Takeda K, Thurman JM, Tomlinson S, Okamoto M, Shiraishi Y, Ferreira VP, Cortes C, Pangburn MK, Holers VM, Gelfand EW. The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation. J Immunol. 2012 Jan 15; 188(2):661-7.
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Kolpakov IY, Vdovenko VN, Stepanova YI, Bazyka DA, Karmaus WJ, Svendsen ER. Functional state of the respiratory and immune system in children-residents of the radioactive contaminated territories. Lik Sprava. 2011 Jan-Mar; (1-2):21-9.
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Brehm JM, Schuemann B, Fuhlbrigge AL, Hollis BW, Strunk RC, Zeiger RS, Weiss ST, Litonjua AA. Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study. J Allergy Clin Immunol. 2010 Jul; 126(1):52-8.e5.
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Lukacs NW, Berlin AA, Franz-Bacon K, Sásik R, Sprague LJ, Ly TW, Hardiman G, Boehme SA, Bacon KB. CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation. Am J Physiol Lung Cell Mol Physiol. 2008 Nov; 295(5):L767-79.
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Warner RL, Lukacs NW, Shapiro SD, Bhagarvathula N, Nerusu KC, Varani J, Johnson KJ. Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen. Am J Pathol. 2004 Dec; 165(6):1921-30.
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Southgate WM, Pichoff BE, Stevens EL, Balaraman V, Uyehara CF, Nakamura KT. Ontogeny of epithelial modulation of airway smooth muscle function in the guinea pig. Pediatr Pulmonol. 1993 Feb; 15(2):105-10.