HIV Envelope Protein gp120
"HIV Envelope Protein gp120" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.
Descriptor ID |
D015699
|
MeSH Number(s) |
D12.776.964.775.325.164.249 D12.776.964.775.562.500.500 D12.776.964.970.880.325.164.249 D23.050.327.520.350
|
Concept/Terms |
HIV Envelope Protein gp120- HIV Envelope Protein gp120
- Envelope Glycoprotein gp120, HIV
- gp120 Envelope Glycoprotein, HIV
- HIV Envelope Glycoprotein gp120
- HTLV-III gp120
- HTLV III gp120
- gp120, HTLV-III
- env Protein gp120, HIV
- gp120(HIV)
|
Below are MeSH descriptors whose meaning is more general than "HIV Envelope Protein gp120".
Below are MeSH descriptors whose meaning is more specific than "HIV Envelope Protein gp120".
This graph shows the total number of publications written about "HIV Envelope Protein gp120" by people in this website by year, and whether "HIV Envelope Protein gp120" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1995 | 1 | 0 | 1 |
2000 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2010 | 1 | 1 | 2 |
2011 | 2 | 1 | 3 |
2013 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "HIV Envelope Protein gp120" by people in Profiles.
-
HIV gp120 induces mucus formation in human bronchial epithelial cells through CXCR4/a7-nicotinic acetylcholine receptors. PLoS One. 2013; 8(10):e77160.
-
Mucosal transmissibility, disease induction and coreceptor switching of R5 SHIVSF162P3N molecular clones in rhesus macaques. Retrovirology. 2013 Jan 31; 10:9.
-
SAXS data analysis and modeling of tetravalent neutralizing antibody CD4-IgG2 -/+ HIV-1 gp120 revealed that first two gp120 bind to the same Fab arm. Biochem Biophys Res Commun. 2011 Dec 02; 415(4):680-5.
-
Nonrandom distribution of cryptic repeating triplets of purines and pyrimidines (RNY)(n) in gp120 of HIV Type1. AIDS Res Hum Retroviruses. 2012 May; 28(5):493-504.
-
Adoption of an "open" envelope conformation facilitating CD4 binding and structural remodeling precedes coreceptor switch in R5 SHIV-infected macaques. PLoS One. 2011; 6(7):e21350.
-
A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement. Virol J. 2010 Jun 29; 7:142.
-
Long sequence duplications, repeats, and palindromes in HIV-1 gp120: length variation in V4 as the product of misalignment mechanism. Virology. 2010 Mar 30; 399(1):167-175.
-
V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies. PLoS Pathog. 2007 Aug 24; 3(8):e117.
-
Matrix fibronectin increases HIV stability and infectivity. J Immunol. 2002 Jun 01; 168(11):5722-9.
-
Superfibronectin, a multimeric form of fibronectin, increases HIV infection of primary CD4+ T lymphocytes. J Immunol. 2000 Mar 15; 164(6):3236-45.