Complement System Proteins

"Complement System Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Serum glycoproteins participating in the host defense mechanism of COMPLEMENT ACTIVATION that creates the COMPLEMENT MEMBRANE ATTACK COMPLEX. Included are glycoproteins in the various pathways of complement activation (CLASSICAL COMPLEMENT PATHWAY; ALTERNATIVE COMPLEMENT PATHWAY; and LECTIN COMPLEMENT PATHWAY).

Descriptor ID	D003165
MeSH Number(s)	D12.776.124.486.274
Concept/Terms	Complement System Proteins Complement System Proteins Proteins, Complement System Complement Protein Protein, Complement Complement Proteins Proteins, Complement Complement Hemolytic Complement Hemolytic Complement Complement, Hemolytic

Below are MeSH descriptors whose meaning is more general than "Complement System Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Immunoproteins [D12.776.124.486]
Complement System Proteins [D12.776.124.486.274]

Below are MeSH descriptors whose meaning is related to "Complement System Proteins".

Below are MeSH descriptors whose meaning is more specific than "Complement System Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Complement System Proteins" by people in this website by year, and whether "Complement System Proteins" was a major or minor topic of these publications.

Bar chart showing 62 publications over 22 distinct years, with a maximum of 5 publications in 2013 and 2014 and 2018 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1999	0	1	1
2001	0	2	2
2002	2	1	3
2003	0	1	1
2004	2	1	3
2005	1	0	1
2006	1	1	2
2007	1	0	1
2008	1	0	1
2010	3	0	3
2011	2	2	4
2012	1	3	4
2013	3	2	5
2014	5	0	5
2015	2	1	3
2016	4	0	4
2017	1	0	1
2018	3	2	5
2019	1	2	3
2020	4	1	5
2021	4	0	4

Below are the most recent publications written about "Complement System Proteins" by people in Profiles.

Savitt AG, Manimala S, White T, Fandaros M, Yin W, Duan H, Xu X, Geisbrecht BV, Rubenstein DA, Kaplan AP, Peerschke EI, Ghebrehiwet B. SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems. Front Immunol. 2021; 12:767347.

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Yarmoska SK, Alawieh AM, Tomlinson S, Hoang KB. Modulation of the Complement System by Neoplastic Disease of the Central Nervous System. Front Immunol. 2021; 12:689435.

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Brennan FH, Coulthard LG, Alawieh AM, Reiner O, Pekna M. Editorial: Complement in the Development and Regeneration of the Nervous System. Front Immunol. 2021; 12:694810.

View in: PubMed
Mallah K, Couch C, Alshareef M, Borucki D, Yang X, Alawieh A, Tomlinson S. Complement mediates neuroinflammation and cognitive decline at extended chronic time points after traumatic brain injury. Acta Neuropathol Commun. 2021 04 20; 9(1):72.

View in: PubMed
Kaplan AP, Ghebrehiwet B. Pathways for bradykinin formation and interrelationship with complement as a cause of edematous lung in COVID-19 patients. J Allergy Clin Immunol. 2021 Feb; 147(2):507-509.

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Borucki DM, Toutonji A, Couch C, Mallah K, Rohrer B, Tomlinson S. Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System. Front Immunol. 2020; 11:566892.

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Balasubramaniam D, Gottwald L, Dominiak N, Rettig N, Bedford-Lyon N, Ahmed M. Hypocomplementemic urticarial vasculitis syndrome: a rare autoimmune entity. Int J Dermatol. 2020 Dec; 59(12):e480-e481.

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Alawieh AM, Langley EF, Feng W, Spiotta AM, Tomlinson S. Complement-Dependent Synaptic Uptake and Cognitive Decline after Stroke and Reperfusion Therapy. J Neurosci. 2020 05 13; 40(20):4042-4058.

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Nguyen H, Alawieh A, Bastian D, Kuril S, Dai M, Daenthanasanmak A, Zhang M, Iamsawat S, Schutt SD, Wu Y, Sleiman MM, Shetty A, Atkinson C, Sun S, Varela JC, Tomlinson S, Yu XZ. Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease. Clin Cancer Res. 2020 07 01; 26(13):3481-3490.

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Aringer M, Costenbader K, Daikh D, Brinks R, Mosca M, Ramsey-Goldman R, Smolen JS, Wofsy D, Boumpas DT, Kamen DL, Jayne D, Cervera R, Costedoat-Chalumeau N, Diamond B, Gladman DD, Hahn B, Hiepe F, Jacobsen S, Khanna D, Lerstrøm K, Massarotti E, McCune J, Ruiz-Irastorza G, Sanchez-Guerrero J, Schneider M, Urowitz M, Bertsias G, Hoyer BF, Leuchten N, Tani C, Tedeschi SK, Touma Z, Schmajuk G, Anic B, Assan F, Chan TM, Clarke AE, Crow MK, Czirják L, Doria A, Graninger W, Halda-Kiss B, Hasni S, Izmirly PM, Jung M, Kumánovics G, Mariette X, Padjen I, Pego-Reigosa JM, Romero-Diaz J, Rúa-Figueroa Fernández Í, Seror R, Stummvoll GH, Tanaka Y, Tektonidou MG, Vasconcelos C, Vital EM, Wallace DJ, Yavuz S, Meroni PL, Fritzler MJ, Naden R, Dörner T, Johnson SR. 2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus. Arthritis Rheumatol. 2019 09; 71(9):1400-1412.

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