Interleukin-7

"Interleukin-7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cytokine produced by bone marrow stromal cells that promotes the growth of B-LYMPHOCYTE precursors and is co-mitogenic with INTERLEUKIN-2 for mature T-LYMPHOCYTE activation.

Descriptor ID	D015851
MeSH Number(s)	D12.644.276.374.465.246 D12.776.467.374.465.224 D23.529.374.465.246
Concept/Terms	Interleukin-7 Interleukin-7 Interleukin 7 IL7 Lymphopoietin-1 Lymphopoietin 1 IL-7

Below are MeSH descriptors whose meaning is more general than "Interleukin-7".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-7 [D12.644.276.374.465.246]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-7 [D12.776.467.374.465.224]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-7 [D23.529.374.465.246]

Below are MeSH descriptors whose meaning is related to "Interleukin-7".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-7".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-7" by people in this website by year, and whether "Interleukin-7" was a major or minor topic of these publications.

Bar chart showing 11 publications over 10 distinct years, with a maximum of 2 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1998	0	1	1
2007	0	1	1
2008	1	1	2
2009	1	0	1
2013	1	0	1
2015	1	0	1
2016	1	0	1
2017	1	0	1

Below are the most recent publications written about "Interleukin-7" by people in Profiles.

Neitzke DJ, Bowers JS, Andrijauskaite K, O'Connell NS, Garrett-Mayer E, Wrangle J, Li Z, Paulos CM, Cole DJ, Rubinstein MP. Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis. Cancer Immunol Immunother. 2017 Jun; 66(6):737-751.

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Milford TA, Su RJ, Francis OL, Baez I, Martinez SR, Coats JS, Weldon AJ, Calderon MN, Nwosu MC, Botimer AR, Suterwala BT, Zhang XB, Morris CL, Weldon DJ, Dovat S, Payne KJ. TSLP or IL-7 provide an IL-7Ra signal that is critical for human B lymphopoiesis. Eur J Immunol. 2016 09; 46(9):2155-61.

View in: PubMed
Johnson CB, Riesenberg BP, May BR, Gilreath SC, Li G, Staveley-O'Carroll KF, Garrett-Mayer E, Mehrotra S, Cole DJ, Rubinstein MP. Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Ra Dependent. Cancer Immunol Res. 2015 Dec; 3(12):1364-74.

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Iolyeva M, Aebischer D, Proulx ST, Willrodt AH, Ecoiffier T, Häner S, Bouchaud G, Krieg C, Onder L, Ludewig B, Santambrogio L, Boyman O, Chen L, Finke D, Halin C. Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage. Blood. 2013 Sep 26; 122(13):2271-81.

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Parrish YK, Baez I, Milford TA, Benitez A, Galloway N, Rogerio JW, Sahakian E, Kagoda M, Huang G, Hao QL, Sevilla Y, Barsky LW, Zielinska E, Price MA, Wall NR, Dovat S, Payne KJ. IL-7 Dependence in human B lymphopoiesis increases during progression of ontogeny from cord blood to bone marrow. J Immunol. 2009 Apr 01; 182(7):4255-66.

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Rubinstein MP, Lind NA, Purton JF, Filippou P, Best JA, McGhee PA, Surh CD, Goldrath AW. IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood. 2008 Nov 01; 112(9):3704-12.

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Ramsey C, Rubinstein MP, Kim DM, Cho JH, Sprent J, Surh CD. The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15. J Immunol. 2008 Apr 15; 180(8):5320-6.

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Purton JF, Tan JT, Rubinstein MP, Kim DM, Sprent J, Surh CD. Antiviral CD4+ memory T cells are IL-15 dependent. J Exp Med. 2007 Apr 16; 204(4):951-61.

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Aiba Y, Ogawa M. Development of natural killer cells from lymphohematopoietic progenitors of murine fetal liver. Stem Cells. 1998; 16 Suppl 1:193-8.

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Ball TC, Hirayama F, Ogawa M. Modulation of early B lymphopoiesis by interleukin-3. Exp Hematol. 1996 Aug; 24(10):1225-31.

View in: PubMed

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