"Nitric Oxide Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH-dependent enzyme that catalyzes the conversion of L-ARGININE and OXYGEN to produce CITRULLINE and NITRIC OXIDE.
| Descriptor ID |
D019001
|
| MeSH Number(s) |
D08.811.682.664.500.772
|
| Concept/Terms |
Nitric Oxide Synthase- Nitric Oxide Synthase
- Oxide Synthase, Nitric
- Synthase, Nitric Oxide
- Nitric-Oxide Synthetase
- Nitric Oxide Synthetase
- NO Synthase
- Nitric-Oxide Synthase
|
Below are MeSH descriptors whose meaning is more general than "Nitric Oxide Synthase".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide Synthase".
This graph shows the total number of publications written about "Nitric Oxide Synthase" by people in this website by year, and whether "Nitric Oxide Synthase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 1 | 1 | 2 |
| 1996 | 2 | 2 | 4 |
| 1997 | 5 | 1 | 6 |
| 1998 | 4 | 3 | 7 |
| 1999 | 2 | 6 | 8 |
| 2000 | 1 | 2 | 3 |
| 2001 | 3 | 2 | 5 |
| 2002 | 7 | 4 | 11 |
| 2003 | 8 | 7 | 15 |
| 2004 | 7 | 8 | 15 |
| 2005 | 8 | 1 | 9 |
| 2006 | 2 | 2 | 4 |
| 2007 | 2 | 0 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nitric Oxide Synthase" by people in Profiles.
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Semenikhina M, Stefanenko M, Spires DR, Ilatovskaya DV, Palygin O. Nitric-Oxide-Mediated Signaling in Podocyte Pathophysiology. Biomolecules. 2022 05 25; 12(6).
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Buie JJ, Renaud LL, Muise-Helmericks R, Oates JC. IFN-a Negatively Regulates the Expression of Endothelial Nitric Oxide Synthase and Nitric Oxide Production: Implications for Systemic Lupus Erythematosus. J Immunol. 2017 09 15; 199(6):1979-1988.
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Zhang J, Grek C, Ye ZW, Manevich Y, Tew KD, Townsend DM. Pleiotropic functions of glutathione S-transferase P. Adv Cancer Res. 2014; 122:143-75.
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Tennyson AG, Lippard SJ. Generation, translocation, and action of nitric oxide in living systems. Chem Biol. 2011 Oct 28; 18(10):1211-20.
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Shao B, Kitchens RL, Munford RS, Rogers TE, Rockey DC, Varley AW. Prolonged hepatomegaly in mice that cannot inactivate bacterial endotoxin. Hepatology. 2011 Sep 02; 54(3):1051-62.
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Manevich Y, Townsend DM, Hutchens S, Tew KD. Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase. PLoS One. 2010 Nov 30; 5(11):e14151.
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Saito C, Lemasters JJ, Jaeschke H. c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity. Toxicol Appl Pharmacol. 2010 Jul; 246(1-2):8-17.
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Belmonte S, Morad M. 'Pressure-flow'-triggered intracellular Ca2+ transients in rat cardiac myocytes: possible mechanisms and role of mitochondria. J Physiol. 2008 Mar 01; 586(5):1379-97.
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Dzavík V, Cotter G, Reynolds HR, Alexander JH, Ramanathan K, Stebbins AL, Hathaway D, Farkouh ME, Ohman EM, Baran DA, Prondzinsky R, Panza JA, Cantor WJ, Vered Z, Buller CE, Kleiman NS, Webb JG, Holmes DR, Parrillo JE, Hazen SL, Gross SS, Harrington RA, Hochman JS. Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study. Eur Heart J. 2007 May; 28(9):1109-16.
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Alexander JH, Reynolds HR, Stebbins AL, Dzavik V, Harrington RA, Van de Werf F, Hochman JS. Effect of tilarginine acetate in patients with acute myocardial infarction and cardiogenic shock: the TRIUMPH randomized controlled trial. JAMA. 2007 Apr 18; 297(15):1657-66.