"Gap Junctions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of CONNEXINS, the family of proteins which form the junctions.
| Descriptor ID |
D017629
|
| MeSH Number(s) |
A11.284.149.165.420.471
|
| Concept/Terms |
Gap Junctions- Gap Junctions
- Gap Junction
- Junction, Gap
- Junctions, Gap
|
Below are MeSH descriptors whose meaning is more general than "Gap Junctions".
Below are MeSH descriptors whose meaning is more specific than "Gap Junctions".
This graph shows the total number of publications written about "Gap Junctions" by people in this website by year, and whether "Gap Junctions" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 1 | 2 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 0 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 2 | 2 | 4 |
| 2011 | 2 | 1 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gap Junctions" by people in Profiles.
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Rog-Zielinska EA, Norris RA, Kohl P, Markwald R. The Living Scar--Cardiac Fibroblasts and the Injured Heart. Trends Mol Med. 2016 Feb; 22(2):99-114.
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Basheer WA, Harris BS, Mentrup HL, Abreha M, Thames EL, Lea JB, Swing DA, Copeland NG, Jenkins NA, Price RL, Matesic LE. Cardiomyocyte-specific overexpression of the ubiquitin ligase Wwp1 contributes to reduction in Connexin 43 and arrhythmogenesis. J Mol Cell Cardiol. 2015 Nov; 88:1-13.
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Yang H, Borg TK, Schmidt LP, Gao BZ. Laser cell-micropatterned pair of cardiomyocytes: the relationship between basement membrane development and gap junction maturation. Biofabrication. 2014 Sep 12; 6(4):045003.
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Grek CL, Rhett JM, Ghatnekar GS. Cardiac to cancer: connecting connexins to clinical opportunity. FEBS Lett. 2014 Apr 17; 588(8):1349-64.
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Rhett JM, Veeraraghavan R, Poelzing S, Gourdie RG. The perinexus: sign-post on the path to a new model of cardiac conduction? Trends Cardiovasc Med. 2013 Aug; 23(6):222-8.
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Tufan H, Zhang XH, Haghshenas N, Sussman MA, Cleemann L, Morad M. Cardiac progenitor cells engineered with Pim-1 (CPCeP) develop cardiac phenotypic electrophysiological properties as they are co-cultured with neonatal myocytes. J Mol Cell Cardiol. 2012 Nov; 53(5):695-706.
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Palatinus JA, Rhett JM, Gourdie RG. The connexin43 carboxyl terminus and cardiac gap junction organization. Biochim Biophys Acta. 2012 Aug; 1818(8):1831-43.
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Rhett JM, Jourdan J, Gourdie RG. Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1. Mol Biol Cell. 2011 May; 22(9):1516-28.
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Hosoda T, Zheng H, Cabral-da-Silva M, Sanada F, Ide-Iwata N, Ogórek B, Ferreira-Martins J, Arranto C, D'Amario D, del Monte F, Urbanek K, D'Alessandro DA, Michler RE, Anversa P, Rota M, Kajstura J, Leri A. Human cardiac stem cell differentiation is regulated by a mircrine mechanism. Circulation. 2011 Mar 29; 123(12):1287-96.
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O'Quinn MP, Palatinus JA, Harris BS, Hewett KW, Gourdie RG. A peptide mimetic of the connexin43 carboxyl terminus reduces gap junction remodeling and induced arrhythmia following ventricular injury. Circ Res. 2011 Mar 18; 108(6):704-15.