John J. Woodward

Title
InstitutionMedical University of South Carolina
DepartmentNeuroscience
AddressP.O. Box MSC 861
456 IOPN
67 President St.
Phone843-792-5225
Fax843-792-7353
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    Dr. Woodward's lab is focused on defining the neural sites of action of alcohol and abused inhalants such as toluene and TCE with an emphasis on cortical based brain circuitry. Alcohol and abused inhalants produce diverse effects on neuronal function by altering the function of different types of ion channels that regulate neuronal excitability. These include voltage dependent channels as well as those gated by neurotransmitters such as glutamate, Ach and ATP. Electrophysiological recording techniques are used to directly measure the function of both recombinant and native channels while site-directed mutagenesis is used to probe for discrete sites of action on the ion channel itself. These approaches are complemented by optogenetic and chemogenetic (DREADD) techniques that provide for more precise control over neuronal function.
    Collapse keywords
    neural basis of action of alcohol and abused inhalants, electrophysiology, ion channels, prefrontal cortex

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nimitvilai-Roberts S, Gioia D, Lopez MF, Glaser CM, Woodward JJ. Chronic intermittent ethanol exposure differentially alters the excitability of neurons in the orbitofrontal cortex and basolateral amygdala that project to the dorsal striatum. Neuropharmacology. 2023 May 01; 228:109463. PMID: 36792030; PMCID: PMC10006395.
      Citations:    Fields:    Translation:AnimalsCells
    2. Woodward JJ, Braunscheidel KM. The Effects of the Inhalant Toluene on Cognitive Function and Behavioral Flexibility: A Review of Recent Findings. Addict Neurosci. 2023 Mar; 5. PMID: 36798693; PMCID: PMC9928149.
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    3. Griffin WC, Lopez MF, Woodward JJ, Becker HC. Alcohol Dependence and the Ventral Hippocampal Influence on Alcohol Drinking in Male Mice. Alcohol. 2022 Oct 31. PMID: 36328184.
      Citations: 1     Fields:    
    4. Nimitvilai-Roberts S, Woodward JJ. The ethanol inhibition of basolateral amygdala neuron spiking is mediated by a ?-aminobutyric acid type A-mediated tonic current. Alcohol Clin Exp Res. 2022 Sep; 46(9):1665-1676. PMID: 35915568; PMCID: PMC9509443.
      Citations: 1     Fields:    Translation:AnimalsCells
    5. Nentwig TB, Vaughan DT, Braunscheidel KM, Browning BD, Woodward JJ, Chandler LJ, Nentwig TB, Vaughan DT, Braunscheidel KM, Browning BD, Woodward JJ, Chandler LJ. The lateral habenula is not required for ethanol dependence-induced escalation of drinking. Neuropsychopharmacology. 2022 11; 47(12):2123-2131. PMID: 35717465; PMCID: PMC9556754.
      Citations: 1     Fields:    Translation:Animals
    6. Braunscheidel KM, Okas MP, Floresco SB, Woodward JJ, Braunscheidel KM, Okas MP, Floresco SB, Woodward JJ. Cannabinoid receptor type 1 antagonists alter aspects of risk/reward decision making independent of toluene-mediated effects. Psychopharmacology (Berl). 2022 May; 239(5):1337-1347. PMID: 34291308; PMCID: PMC9885490.
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    7. Nimitvilai-Roberts S, Gioia D, Zamudio PA, Woodward JJ. Ethanol inhibition of lateral orbitofrontal cortex neuron excitability is mediated via dopamine D1/D5 receptor-induced release of astrocytic glycine. Neuropharmacology. 2021 07 01; 192:108600. PMID: 33965399; PMCID: PMC8217293.
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    8. Gioia DA, Woodward JJ, Gioia DA, Woodward JJ. Altered Activity of Lateral Orbitofrontal Cortex Neurons in Mice following Chronic Intermittent Ethanol Exposure. eNeuro. 2021 Mar-Apr; 8(2). PMID: 33593732; PMCID: PMC7932186.
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    9. Avchalumov Y, Piña-Crespo JC, Woodward JJ, Mandyam CD, Avchalumov Y, Pi?a-Crespo JC, Woodward JJ, Mandyam CD. Acute Ethanol Exposure Enhances Synaptic Plasticity in the Dorsal Striatum in Adult Male and Female Rats. Brain Plast. 2020 Dec 29; 6(1):113-122. PMID: 33680850; PMCID: PMC7903017.
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    10. Avchalumov Y, Oliver RJ, Trenet W, Heyer Osorno RE, Sibley BD, Purohit DC, Contet C, Roberto M, Woodward JJ, Mandyam CD, Avchalumov Y, Oliver RJ, Trenet W, Heyer Osorno RE, Sibley BD, Purohit DC, Contet C, Roberto M, Woodward JJ, Mandyam CD. Chronic ethanol exposure differentially alters neuronal function in the medial prefrontal cortex and dentate gyrus. Neuropharmacology. 2021 03 01; 185:108438. PMID: 33333103; PMCID: PMC7927349.
      Citations:    
    11. Cannady R, Nguyen T, Padula AE, Rinker JA, Lopez MF, Becker HC, Woodward JJ, Mulholland PJ, Cannady R, Nguyen T, Padula AE, Rinker JA, Lopez MF, Becker HC, Woodward JJ, Mulholland PJ. Interaction of chronic intermittent ethanol and repeated stress on structural and functional plasticity in the mouse medial prefrontal cortex. Neuropharmacology. 2021 01; 182:108396. PMID: 33181147; PMCID: PMC7942177.
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    12. Zamudio PA, Gioia DA, Lopez M, Homanics GE, Woodward JJ. The escalation in ethanol consumption following chronic intermittent ethanol exposure is blunted in mice expressing ethanol-resistant GluN1 or GluN2A NMDA receptor subunits. Psychopharmacology (Berl). 2021 Jan; 238(1):271-279. PMID: 33052417; PMCID: PMC7796987.
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    13. Braunscheidel KM, Wayman WN, Okas MP, Woodward JJ, Braunscheidel KM, Wayman WN, Okas MP, Woodward JJ. Self-Administration of Toluene Vapor in Rats. Front Neurosci. 2020; 14:880. PMID: 32973434; PMCID: PMC7461949.
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    14. Samantaray S, Knaryan VH, M Del Re A, Woodward JJ, Shields DC, Azuma M, Inoue J, Ray SK, Banik NL, Samantaray S, Knaryan VH, M Del Re A, Woodward JJ, Shields DC, Azuma M, Inoue J, Ray SK, Banik NL. Cell-Permeable Calpain Inhibitor SJA6017 Provides Functional Protection to Spinal Motoneurons Exposed to MPP. Neurotox Res. 2020 Oct; 38(3):640-649. PMID: 32761446; PMCID: PMC9453439.
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    15. Cannady R, Nimitvilai-Roberts S, Jennings SD, Woodward JJ, Mulholland PJ, Cannady R, Nimitvilai-Roberts S, Jennings SD, Woodward JJ, Mulholland PJ. Distinct Region- and Time-Dependent Functional Cortical Adaptations in C57BL/6J Mice after Short and Prolonged Alcohol Drinking. eNeuro. 2020 May/Jun; 7(3). PMID: 32439714; PMCID: PMC7307629.
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    16. O'Herron P, Levy M, Woodward JJ, Kara P, O'Herron P, Levy M, Woodward JJ, Kara P. An Unexpected Dependence of Cortical Depth in Shaping Neural Responsiveness and Selectivity in Mouse Visual Cortex. eNeuro. 2020 Mar/Apr; 7(2). PMID: 32051142; PMCID: PMC7092962.
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    17. Zamudio PA, Smothers TC, Homanics GE, Woodward JJ. Knock-in Mice Expressing an Ethanol-Resistant GluN2A NMDA Receptor Subunit Show Altered Responses to Ethanol. Alcohol Clin Exp Res. 2020 02; 44(2):479-491. PMID: 31872888; PMCID: PMC7018579.
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    18. O'Herron P, Summers PM, Shih AY, Kara P, Woodward JJ, O'Herron P, Summers PM, Shih AY, Kara P, Woodward JJ. In?vivo two-photon imaging of neuronal and brain vascular responses in mice chronically exposed to ethanol. Alcohol. 2020 06; 85:41-47. PMID: 31857103; PMCID: PMC7237312.
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    19. Braunscheidel KM, Okas MP, Hoffman M, Mulholland PJ, Floresco SB, Woodward JJ, Braunscheidel KM, Okas MP, Hoffman M, Mulholland PJ, Floresco SB, Woodward JJ. The Abused Inhalant Toluene Impairs Medial Prefrontal Cortex Activity and Risk/Reward Decision-Making during a Probabilistic Discounting Task. J Neurosci. 2019 11 13; 39(46):9207-9220. PMID: 31548237; PMCID: PMC6855687.
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    20. Nimitvilai S, Lopez MF, Woodward JJ, Nimitvilai S, Lopez MF, Woodward JJ. Sex-dependent differences in ethanol inhibition of mouse lateral orbitofrontal cortex neurons. Addict Biol. 2020 01; 25(1):e12698. PMID: 30468275; PMCID: PMC8168337.
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    21. Haun HL, Griffin WC, Lopez MF, Solomon MG, Mulholland PJ, Woodward JJ, McGinty JF, Ron D, Becker HC, Haun HL, Griffin WC, Lopez MF, Solomon MG, Mulholland PJ, Woodward JJ, McGinty JF, Ron D, Becker HC. Increasing Brain-Derived Neurotrophic Factor (BDNF) in medial prefrontal cortex selectively reduces excessive drinking in ethanol dependent mice. Neuropharmacology. 2018 09 15; 140:35-42. PMID: 30056122; PMCID: PMC6113096.
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    22. Harlan BA, Becker HC, Woodward JJ, Riegel AC, Harlan BA, Becker HC, Woodward JJ, Riegel AC. Opposing actions of CRF-R1 and CB1 receptors on VTA-GABAergic plasticity following chronic exposure to ethanol. Neuropsychopharmacology. 2018 09; 43(10):2064-2074. PMID: 29946104; PMCID: PMC6098046.
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    23. Nimitvilai S, Lopez MF, Woodward JJ, Nimitvilai S, Lopez MF, Woodward JJ. Effects of monoamines on the intrinsic excitability of lateral orbitofrontal cortex neurons in alcohol-dependent and non-dependent female mice. Neuropharmacology. 2018 07 15; 137:1-12. PMID: 29689260; PMCID: PMC6050070.
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    24. Gioia DA, Xu M, Wayman WN, Woodward JJ, Gioia DA, Xu M, Wayman WN, Woodward JJ. Effects of drugs of abuse on channelrhodopsin-2 function. Neuropharmacology. 2018 06; 135:316-327. PMID: 29580953; PMCID: PMC5975088.
      Citations:    
    25. Zamudio-Bulcock PA, Homanics GE, Woodward JJ, Zamudio-Bulcock PA, Homanics GE, Woodward JJ. Loss of Ethanol Inhibition of N-Methyl-D-Aspartate Receptor-Mediated Currents and Plasticity of Cerebellar Synapses in Mice Expressing the GluN1(F639A) Subunit. Alcohol Clin Exp Res. 2018 Apr; 42(4):698-705. PMID: 29323417; PMCID: PMC5880713.
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    26. Wayman WN, Woodward JJ, Wayman WN, Woodward JJ. Chemogenetic Excitation of Accumbens-Projecting Infralimbic Cortical Neurons Blocks Toluene-Induced Conditioned Place Preference. J Neurosci. 2018 02 07; 38(6):1462-1471. PMID: 29317484; PMCID: PMC5815347.
      Citations:    
    27. Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ, Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ. Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior. Handb Exp Pharmacol. 2018; 248:311-343. PMID: 29374839; PMCID: PMC8252120.
      Citations:    
    28. Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ, Cannady R, Rinker JA, Nimitvilai S, Woodward JJ, Mulholland PJ. Correction to: Chronic Alcohol, Intrinsic Excitability, and Potassium Channels: Neuroadaptations and Drinking Behavior. Handb Exp Pharmacol. 2018; 248:619. PMID: 30810861.
      Citations:    
    29. Braunscheidel KM, Gass JT, Mulholland PJ, Floresco SB, Woodward JJ, Braunscheidel KM, Gass JT, Mulholland PJ, Floresco SB, Woodward JJ. Persistent cognitive and morphological alterations induced by repeated exposure of adolescent rats to the abused inhalant toluene. Neurobiol Learn Mem. 2017 Oct; 144:136-146. PMID: 28720405; PMCID: PMC5583007.
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    30. Wayman WN, Woodward JJ, Wayman WN, Woodward JJ. Exposure to the Abused Inhalant Toluene Alters Medial Prefrontal Cortex Physiology. Neuropsychopharmacology. 2018 03; 43(4):912-924. PMID: 28589963; PMCID: PMC5809778.
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    31. Cannady R, McGonigal JT, Newsom RJ, Woodward JJ, Mulholland PJ, Gass JT, Cannady R, McGonigal JT, Newsom RJ, Woodward JJ, Mulholland PJ, Gass JT. Prefrontal Cortex KCa2 Channels Regulate mGlu5-Dependent Plasticity and Extinction of Alcohol-Seeking Behavior. J Neurosci. 2017 04 19; 37(16):4359-4369. PMID: 28320841; PMCID: PMC5413180.
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    32. Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ, Nimitvilai S, Uys JD, Woodward JJ, Randall PK, Ball LE, Williams RW, Jones BC, Lu L, Grant KA, Mulholland PJ. Orbitofrontal Neuroadaptations and Cross-Species Synaptic Biomarkers in Heavy-Drinking Macaques. J Neurosci. 2017 03 29; 37(13):3646-3660. PMID: 28270566; PMCID: PMC5373140.
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    33. den Hartog CR, Gilstrap M, Eaton B, Lench DH, Mulholland PJ, Homanics GE, Woodward JJ, den Hartog CR, Gilstrap M, Eaton B, Lench DH, Mulholland PJ, Homanics GE, Woodward JJ. Effects of Repeated Ethanol Exposures on NMDA Receptor Expression and Locomotor Sensitization in Mice Expressing Ethanol Resistant NMDA Receptors. Front Neurosci. 2017; 11:84. PMID: 28270746; PMCID: PMC5318453.
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    34. Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ, Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ. Ethanol Dependence Abolishes Monoamine and GIRK (Kir3) Channel Inhibition of Orbitofrontal Cortex Excitability. Neuropsychopharmacology. 2017 Aug; 42(9):1800-1812. PMID: 28139680; PMCID: PMC5520780.
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    35. Smothers CT, Woodward JJ, Smothers CT, Woodward JJ. Differential effects of TM4 tryptophan mutations on inhibition of N-methyl-d-aspartate receptors by ethanol and toluene. Alcohol. 2016 11; 56:15-19. PMID: 27814790; PMCID: PMC5542567.
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    36. Nimitvilai S, You C, Arora DS, McElvain MA, Vandegrift BJ, Brodie MS, Woodward JJ, Nimitvilai S, You C, Arora DS, McElvain MA, Vandegrift BJ, Brodie MS, Woodward JJ. Differential Effects of Toluene and Ethanol on Dopaminergic Neurons of the Ventral Tegmental Area. Front Neurosci. 2016; 10:434. PMID: 27713687; PMCID: PMC5031606.
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    37. Tabakoff B, Ren W, Vanderlinden L, Snell LD, Matheson CJ, Wang ZJ, Levinson R, Smothers CT, Woodward JJ, Honse Y, Lovinger D, Rush AM, Sather WA, Gustafson DL, Hoffman PL, Tabakoff B, Ren W, Vanderlinden L, Snell LD, Matheson CJ, Wang ZJ, Levinson R, Smothers CT, Woodward JJ, Honse Y, Lovinger D, Rush AM, Sather WA, Gustafson DL, Hoffman PL. A novel substituted aminoquinoline selectively targets voltage-sensitive sodium channel isoforms and NMDA receptor subtypes and alleviates chronic inflammatory and neuropathic pain. Eur J Pharmacol. 2016 Aug 05; 784:1-14. PMID: 27158117; PMCID: PMC5024723.
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    38. den Hartog C, Zamudio-Bulcock P, Nimitvilai S, Gilstrap M, Eaton B, Fedarovich H, Motts A, Woodward JJ, den Hartog C, Zamudio-Bulcock P, Nimitvilai S, Gilstrap M, Eaton B, Fedarovich H, Motts A, Woodward JJ. Inactivation of the lateral orbitofrontal cortex increases drinking in ethanol-dependent but not non-dependent mice. Neuropharmacology. 2016 08; 107:451-459. PMID: 27016020; PMCID: PMC4934018.
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    39. Tomko RL, Prisciandaro JJ, Falls SK, Magid V, Tomko RL, Prisciandaro JJ, Falls SK, Magid V. The structure of the UPPS-R-Child impulsivity scale and its relations with substance use outcomes among treatment-seeking adolescents. Drug Alcohol Depend. 2016 Apr 01; 161:276-83. PMID: 26905208; PMCID: PMC4799694.
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    40. Lopez MF, Anderson RI, Becker HC, Lopez MF, Anderson RI, Becker HC. Effect of different stressors on voluntary ethanol intake in ethanol-dependent and nondependent C57BL/6J mice. Alcohol. 2016 Mar; 51:17-23. PMID: 26992696; PMCID: PMC4799834.
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    41. Hughes BA, Woodward JJ, Hughes BA, Woodward JJ. Disruption of S2-M4 linker coupling reveals novel subunit-specific contributions to N-methyl-d-aspartate receptor function and ethanol sensitivity. Neuropharmacology. 2016 06; 105:96-105. PMID: 26577016; PMCID: PMC4864172.
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    42. Smothers CT, Szumlinski KK, Worley PF, Woodward JJ, Smothers CT, Szumlinski KK, Worley PF, Woodward JJ. Altered NMDA receptor function in primary cultures of hippocampal neurons from mice lacking the Homer2 gene. Synapse. 2016 Jan; 70(1):33-9. PMID: 26426435; PMCID: PMC4654643.
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    43. Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ, Nimitvilai S, Lopez MF, Mulholland PJ, Woodward JJ. Chronic Intermittent Ethanol Exposure Enhances the Excitability and Synaptic Plasticity of Lateral Orbitofrontal Cortex Neurons and Induces a Tolerance to the Acute Inhibitory Actions of Ethanol. Neuropsychopharmacology. 2016 Mar; 41(4):1112-27. PMID: 26286839; PMCID: PMC4748436.
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    44. Beckley JT, Randall PK, Smith RJ, Hughes BA, Kalivas PW, Woodward JJ, Beckley JT, Randall PK, Smith RJ, Hughes BA, Kalivas PW, Woodward JJ. Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene. Addict Biol. 2016 May; 21(3):530-46. PMID: 25752326; PMCID: PMC4561223.
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    45. Orr RK, Hoehn JL, Col NF, Padula AE, Griffin WC, Lopez MF, Nimitvilai S, Cannady R, McGuier NS, Chesler EJ, Miles MF, Williams RW, Randall PK, Woodward JJ, Becker HC, Mulholland PJ. KCNN Genes that Encode Small-Conductance Ca2+-Activated K+ Channels Influence Alcohol and Drug Addiction. Neuropsychopharmacology. 2015 Jul; 40(8):1928-39. PMID: 25662840; PMCID: PMC4839516.
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    46. Xu M, Smothers CT, Woodward JJ, Xu M, Smothers CT, Woodward JJ. Cysteine substitution of transmembrane domain amino acids alters the ethanol inhibition of GluN1/GluN2A N-methyl-D-aspartate receptors. J Pharmacol Exp Ther. 2015 Apr; 353(1):91-101. PMID: 25635140; PMCID: PMC4366756.
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    47. McGuier NS, Padula AE, Lopez MF, Woodward JJ, Mulholland PJ, McGuier NS, Padula AE, Lopez MF, Woodward JJ, Mulholland PJ. Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice. Alcohol. 2015 Feb; 49(1):21-7. PMID: 25468278; PMCID: PMC4314373.
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    48. Pava MJ, Woodward JJ, Pava MJ, Woodward JJ. Chronic ethanol alters network activity and endocannabinoid signaling in the prefrontal cortex. Front Integr Neurosci. 2014; 8:58. PMID: 25100953; PMCID: PMC4103173.
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    49. Mahler SV, Vazey EM, Beckley JT, Keistler CR, McGlinchey EM, Kaufling J, Wilson SP, Deisseroth K, Woodward JJ, Aston-Jones G, Mahler SV, Vazey EM, Beckley JT, Keistler CR, McGlinchey EM, Kaufling J, Wilson SP, Deisseroth K, Woodward JJ, Aston-Jones G. Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking. Nat Neurosci. 2014 Apr; 17(4):577-85. PMID: 24584054; PMCID: PMC3973180.
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    50. Pava MJ, den Hartog CR, Blanco-Centurion C, Shiromani PJ, Woodward JJ, Pava MJ, den Hartog CR, Blanco-Centurion C, Shiromani PJ, Woodward JJ. Endocannabinoid modulation of cortical up-states and NREM sleep. PLoS One. 2014; 9(2):e88672. PMID: 24520411; PMCID: PMC3919802.
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    51. Cruz SL, Rivera-García MT, Woodward JJ, Cruz SL, Rivera-Garc?a MT, Woodward JJ. Review of toluene action: clinical evidence, animal studies and molecular targets. J Drug Alcohol Res. 2014; 3. PMID: 25360325; PMCID: PMC4211428.
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    52. Woodward JJ, Beckley J, Woodward JJ, Beckley J. Effects of the abused inhalant toluene on the mesolimbic dopamine system. J Drug Alcohol Res. 2014; 3. PMID: 25360326; PMCID: PMC4211636.
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    53. den Hartog CR, Beckley JT, Smothers TC, Lench DH, Holseberg ZL, Fedarovich H, Gilstrap MJ, Homanics GE, Woodward JJ, den Hartog CR, Beckley JT, Smothers TC, Lench DH, Holseberg ZL, Fedarovich H, Gilstrap MJ, Homanics GE, Woodward JJ. Alterations in ethanol-induced behaviors and consumption in knock-in mice expressing ethanol-resistant NMDA receptors. PLoS One. 2013; 8(11):e80541. PMID: 24244696; PMCID: PMC3828265.
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    54. Beckley JT, Woodward JJ, Beckley JT, Woodward JJ. Volatile solvents as drugs of abuse: focus on the cortico-mesolimbic circuitry. Neuropsychopharmacology. 2013 Dec; 38(13):2555-67. PMID: 23954847; PMCID: PMC3828545.
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    55. Smothers CT, Jin C, Woodward JJ, Smothers CT, Jin C, Woodward JJ. Deletion of the N-terminal domain alters the ethanol inhibition of N-methyl-D-aspartate receptors in a subunit-dependent manner. Alcohol Clin Exp Res. 2013 Nov; 37(11):1882-90. PMID: 23905549; PMCID: PMC3812356.
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    56. Hughes BA, Smothers CT, Woodward JJ, Hughes BA, Smothers CT, Woodward JJ. Dephosphorylation of GluN2B C-terminal tyrosine residues does not contribute to acute ethanol inhibition of recombinant NMDA receptors. Alcohol. 2013 May; 47(3):181-6. PMID: 23357553; PMCID: PMC3617063.
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    57. Badanich KA, Mulholland PJ, Beckley JT, Trantham-Davidson H, Woodward JJ, Badanich KA, Mulholland PJ, Beckley JT, Trantham-Davidson H, Woodward JJ. Ethanol reduces neuronal excitability of lateral orbitofrontal cortex neurons via a glycine receptor dependent mechanism. Neuropsychopharmacology. 2013 Jun; 38(7):1176-88. PMID: 23314219; PMCID: PMC3656360.
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    58. Orr RK, Hoehn JL, Col NF, Beckley JT, Evins CE, Fedarovich H, Gilstrap MJ, Woodward JJ. Medial prefrontal cortex inversely regulates toluene-induced changes in markers of synaptic plasticity of mesolimbic dopamine neurons. J Neurosci. 2013 Jan 09; 33(2):804-13. PMID: 23303956; PMCID: PMC3542971.
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    59. Pava MJ, Woodward JJ, Pava MJ, Woodward JJ. A review of the interactions between alcohol and the endocannabinoid system: implications for alcohol dependence and future directions for research. Alcohol. 2012 May; 46(3):185-204. PMID: 22459871; PMCID: PMC3327810.
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    60. Diaz MR, Wadleigh A, Hughes BA, Woodward JJ, Valenzuela CF, Diaz MR, Wadleigh A, Hughes BA, Woodward JJ, Valenzuela CF. Bestrophin1 Channels are Insensitive to Ethanol and Do not Mediate Tonic GABAergic Currents in Cerebellar Granule Cells. Front Neurosci. 2011; 5:148. PMID: 22275879; PMCID: PMC3257865.
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    61. Woodward JJ, Pava M, Woodward JJ, Pava M. Ethanol inhibition of up-states in prefrontal cortical neurons expressing the genetically encoded calcium indicator GCaMP3. Alcohol Clin Exp Res. 2012 May; 36(5):780-7. PMID: 22141337; PMCID: PMC3297730.
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    62. Badanich KA, Becker HC, Woodward JJ, Badanich KA, Becker HC, Woodward JJ. Effects of chronic intermittent ethanol exposure on orbitofrontal and medial prefrontal cortex-dependent behaviors in mice. Behav Neurosci. 2011 Dec; 125(6):879-91. PMID: 22122149; PMCID: PMC3229192.
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    63. Xu M, Smothers CT, Trudell J, Woodward JJ, Xu M, Smothers CT, Trudell J, Woodward JJ. Ethanol inhibition of constitutively open N-methyl-D-aspartate receptors. J Pharmacol Exp Ther. 2012 Jan; 340(1):218-26. PMID: 22005043; PMCID: PMC3251024.
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    64. Pava MJ, Blake EM, Green ST, Mizroch BJ, Mulholland PJ, Woodward JJ, Pava MJ, Blake EM, Green ST, Mizroch BJ, Mulholland PJ, Woodward JJ. Tolerance to cannabinoid-induced behaviors in mice treated chronically with ethanol. Psychopharmacology (Berl). 2012 Jan; 219(1):137-47. PMID: 21701813; PMCID: PMC3249519.
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    65. Beckley JT, Woodward JJ, Beckley JT, Woodward JJ. The abused inhalant toluene differentially modulates excitatory and inhibitory synaptic transmission in deep-layer neurons of the medial prefrontal cortex. Neuropsychopharmacology. 2011 Jun; 36(7):1531-42. PMID: 21430649; PMCID: PMC3096820.
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    66. Xu M, Smothers CT, Woodward JJ, Xu M, Smothers CT, Woodward JJ. Effects of ethanol on phosphorylation site mutants of recombinant N-methyl-D-aspartate receptors. Alcohol. 2011 Jun; 45(4):373-80. PMID: 21163614; PMCID: PMC3095724.
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    67. Mulholland PJ, Becker HC, Woodward JJ, Chandler LJ, Mulholland PJ, Becker HC, Woodward JJ, Chandler LJ. Small conductance calcium-activated potassium type 2 channels regulate alcohol-associated plasticity of glutamatergic synapses. Biol Psychiatry. 2011 Apr 01; 69(7):625-32. PMID: 21056409; PMCID: PMC3103782.
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    68. Das A, McDowell M, Pava MJ, Smith JA, Reiter RJ, Woodward JJ, Varma AK, Ray SK, Banik NL, Das A, McDowell M, Pava MJ, Smith JA, Reiter RJ, Woodward JJ, Varma AK, Ray SK, Banik NL. The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors. J Pineal Res. 2010 Mar; 48(2):157-69. PMID: 20082663; PMCID: PMC2862889.
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    69. Abernathy K, Chandler LJ, Woodward JJ, Abernathy K, Chandler LJ, Woodward JJ. Alcohol and the prefrontal cortex. Int Rev Neurobiol. 2010; 91:289-320. PMID: 20813246; PMCID: PMC3593065.
      Citations:    
    70. Woodward JJ, Pava MJ, Woodward JJ, Pava MJ. Effects of ethanol on persistent activity and up-States in excitatory and inhibitory neurons in prefrontal cortex. Alcohol Clin Exp Res. 2009 Dec; 33(12):2134-40. PMID: 19764936; PMCID: PMC2921674.
      Citations:    
    71. Smothers CT, Woodward JJ, Smothers CT, Woodward JJ. Expression of glycine-activated diheteromeric NR1/NR3 receptors in human embryonic kidney 293 cells Is NR1 splice variant-dependent. J Pharmacol Exp Ther. 2009 Dec; 331(3):975-84. PMID: 19726695; PMCID: PMC2784711.
      Citations:    
    72. Sribnick EA, Del Re AM, Ray SK, Woodward JJ, Banik NL, Sribnick EA, Del Re AM, Ray SK, Woodward JJ, Banik NL. Estrogen attenuates glutamate-induced cell death by inhibiting Ca2+ influx through L-type voltage-gated Ca2+ channels. Brain Res. 2009 Jun 18; 1276:159-70. PMID: 19389388; PMCID: PMC2700344.
      Citations:    
    73. Sas AR, Bimonte-Nelson H, Smothers CT, Woodward J, Tyor WR, Sas AR, Bimonte-Nelson H, Smothers CT, Woodward J, Tyor WR. Interferon-alpha causes neuronal dysfunction in encephalitis. J Neurosci. 2009 Mar 25; 29(12):3948-55. PMID: 19321791; PMCID: PMC3598587.
      Citations:    
    74. Mulholland PJ, Carpenter-Hyland EP, Woodward JJ, Chandler LJ, Mulholland PJ, Carpenter-Hyland EP, Woodward JJ, Chandler LJ. Ethanol disrupts NMDA receptor and astroglial EAAT2 modulation of Kv2.1 potassium channels in hippocampus. Alcohol. 2009 Feb; 43(1):45-50. PMID: 19185209; PMCID: PMC2674284.
      Citations:    
    75. Mulholland PJ, Carpenter-Hyland EP, Hearing MC, Becker HC, Woodward JJ, Chandler LJ, Mulholland PJ, Carpenter-Hyland EP, Hearing MC, Becker HC, Woodward JJ, Chandler LJ. Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels. J Neurosci. 2008 Aug 27; 28(35):8801-9. PMID: 18753382; PMCID: PMC2612131.
      Citations:    
    76. Asatryan L, Popova M, Woodward JJ, King BF, Alkana RL, Davies DL, Asatryan L, Popova M, Woodward JJ, King BF, Alkana RL, Davies DL. Roles of ectodomain and transmembrane regions in ethanol and agonist action in purinergic P2X2 and P2X3 receptors. Neuropharmacology. 2008 Oct; 55(5):835-43. PMID: 18639563; PMCID: PMC2629788.
      Citations:    
    77. Xu M, Chandler LJ, Woodward JJ, Xu M, Chandler LJ, Woodward JJ. Ethanol inhibition of recombinant NMDA receptors is not altered by coexpression of CaMKII-alpha or CaMKII-beta. Alcohol. 2008 Aug; 42(5):425-32. PMID: 18562151; PMCID: PMC2629600.
      Citations:    
    78. Jin C, Smothers CT, Woodward JJ, Jin C, Smothers CT, Woodward JJ. Enhanced ethanol inhibition of recombinant N-methyl-D-aspartate receptors by magnesium: role of NR3A subunits. Alcohol Clin Exp Res. 2008 Jun; 32(6):1059-66. PMID: 18445116; PMCID: PMC3590455.
      Citations:    
    79. Weitlauf C, Woodward JJ, Weitlauf C, Woodward JJ. Ethanol selectively attenuates NMDAR-mediated synaptic transmission in the prefrontal cortex. Alcohol Clin Exp Res. 2008 Apr; 32(4):690-8. PMID: 18341645; PMCID: PMC3587142.
      Citations:    
    80. Woodward JJ, Woodward JJ. GABAA alpha 4 receptor subunits and ethanol: a knockout punch? Alcohol Clin Exp Res. 2008 Jan; 32(1):8-9. PMID: 18070251.
      Citations:    
    81. Mulholland PJ, Luong NT, Woodward JJ, Chandler LJ, Mulholland PJ, Luong NT, Woodward JJ, Chandler LJ. Brain-derived neurotrophic factor activation of extracellular signal-regulated kinase is autonomous from the dominant extrasynaptic NMDA receptor extracellular signal-regulated kinase shutoff pathway. Neuroscience. 2008 Jan 24; 151(2):419-27. PMID: 18055129; PMCID: PMC2390783.
      Citations:    
    82. Smothers CT, Woodward JJ, Smothers CT, Woodward JJ. Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits. J Pharmacol Exp Ther. 2007 Aug; 322(2):739-48. PMID: 17502428.
      Citations:    
    83. Tu Y, Kroener S, Abernathy K, Lapish C, Seamans J, Chandler LJ, Woodward JJ, Tu Y, Kroener S, Abernathy K, Lapish C, Seamans J, Chandler LJ, Woodward JJ. Ethanol inhibits persistent activity in prefrontal cortical neurons. J Neurosci. 2007 Apr 25; 27(17):4765-75. PMID: 17460089; PMCID: PMC3625968.
      Citations:    
    84. Ogata J, Shiraishi M, Namba T, Smothers CT, Woodward JJ, Harris RA, Ogata J, Shiraishi M, Namba T, Smothers CT, Woodward JJ, Harris RA. Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther. 2006 Jul; 318(1):434-43. PMID: 16622040.
      Citations:    
    85. Del Re AM, Dopico AM, Woodward JJ, Del Re AM, Dopico AM, Woodward JJ. Effects of the abused inhalant toluene on ethanol-sensitive potassium channels expressed in oocytes. Brain Res. 2006 May 04; 1087(1):75-82. PMID: 16626657.
      Citations:    
    86. Das A, Garner DP, Del Re AM, Woodward JJ, Kumar DM, Agarwal N, Banik NL, Ray SK, Das A, Garner DP, Del Re AM, Woodward JJ, Kumar DM, Agarwal N, Banik NL, Ray SK. Calpeptin provides functional neuroprotection to rat retinal ganglion cells following Ca2+ influx. Brain Res. 2006 Apr 21; 1084(1):146-57. PMID: 16600192.
      Citations:    
    87. Jin C, Woodward JJ, Jin C, Woodward JJ. Effects of 8 different NR1 splice variants on the ethanol inhibition of recombinant NMDA receptors. Alcohol Clin Exp Res. 2006 Apr; 30(4):673-9. PMID: 16573586.
      Citations:    
    88. Xu M, Woodward JJ, Xu M, Woodward JJ. Ethanol inhibition of NMDA receptors under conditions of altered protein kinase A activity. J Neurochem. 2006 Mar; 96(6):1760-7. PMID: 16539691.
      Citations:    
    89. Smothers CT, Woodward JJ, Smothers CT, Woodward JJ. Effects of amino acid substitutions in transmembrane domains of the NR1 subunit on the ethanol inhibition of recombinant N-methyl-D-aspartate receptors. Alcohol Clin Exp Res. 2006 Mar; 30(3):523-30. PMID: 16499494.
      Citations:    
    90. Davies DL, Asatryan L, Kuo ST, Woodward JJ, King BF, Alkana RL, Xiao C, Ye JH, Sun H, Zhang L, Hu XQ, Hayrapetyan V, Lovinger DM, Machu TK, Davies DL, Asatryan L, Kuo ST, Woodward JJ, King BF, Alkana RL, Xiao C, Ye JH, Sun H, Zhang L, Hu XQ, Hayrapetyan V, Lovinger DM, Machu TK. Effects of ethanol on adenosine 5'-triphosphate-gated purinergic and 5-hydroxytryptamine receptors. Alcohol Clin Exp Res. 2006 Feb; 30(2):349-58. PMID: 16441284; PMCID: PMC1448702.
      Citations:    
    91. Woodward JJ, Ron D, Winder D, Roberto M, Woodward JJ, Ron D, Winder D, Roberto M. From blue states to up states: a regional view of NMDA-ethanol interactions. Alcohol Clin Exp Res. 2006 Feb; 30(2):359-67. PMID: 16441285.
      Citations:    
    92. Shafer TJ, Bushnell PJ, Benignus VA, Woodward JJ, Shafer TJ, Bushnell PJ, Benignus VA, Woodward JJ. Perturbation of voltage-sensitive Ca2+ channel function by volatile organic solvents. J Pharmacol Exp Ther. 2005 Dec; 315(3):1109-18. PMID: 16109744.
      Citations:    
    93. Das A, Sribnick EA, Wingrave JM, Del Re AM, Woodward JJ, Appel SH, Banik NL, Ray SK, Das A, Sribnick EA, Wingrave JM, Del Re AM, Woodward JJ, Appel SH, Banik NL, Ray SK. Calpain activation in apoptosis of ventral spinal cord 4.1 (VSC4.1) motoneurons exposed to glutamate: calpain inhibition provides functional neuroprotection. J Neurosci Res. 2005 Aug 15; 81(4):551-62. PMID: 15968645.
      Citations:    
    94. Davies DL, Kochegarov AA, Kuo ST, Kulkarni AA, Woodward JJ, King BF, Alkana RL, Davies DL, Kochegarov AA, Kuo ST, Kulkarni AA, Woodward JJ, King BF, Alkana RL. Ethanol differentially affects ATP-gated P2X(3) and P2X(4) receptor subtypes expressed in Xenopus oocytes. Neuropharmacology. 2005 Aug; 49(2):243-53. PMID: 15993446.
      Citations:    
    95. Bale AS, Tu Y, Carpenter-Hyland EP, Chandler LJ, Woodward JJ, Bale AS, Tu Y, Carpenter-Hyland EP, Chandler LJ, Woodward JJ. Alterations in glutamatergic and gabaergic ion channel activity in hippocampal neurons following exposure to the abused inhalant toluene. Neuroscience. 2005; 130(1):197-206. PMID: 15561435.
      Citations:    
    96. Del Re AM, Woodward JJ, Del Re AM, Woodward JJ. Inhibition of gap junction currents by the abused solvent toluene. Drug Alcohol Depend. 2005 May 09; 78(2):221-4. PMID: 15845326.
      Citations:    
    97. Woodward JJ, Woodward JJ. Fyn kinase does not reduce ethanol inhibition of zinc-insensitive NR2A-containing N-methyl-D-aspartate receptors. Alcohol. 2004 Oct-Nov; 34(2-3):101-5. PMID: 15902902.
      Citations:    
    98. Carpenter-Hyland EP, Woodward JJ, Chandler LJ, Carpenter-Hyland EP, Woodward JJ, Chandler LJ. Chronic ethanol induces synaptic but not extrasynaptic targeting of NMDA receptors. J Neurosci. 2004 Sep 08; 24(36):7859-68. PMID: 15356198; PMCID: PMC6729936.
      Citations:    
    99. Woodward JJ, Nowak M, Davies DL, Woodward JJ, Nowak M, Davies DL. Effects of the abused solvent toluene on recombinant P2X receptors expressed in HEK293 cells. Brain Res Mol Brain Res. 2004 Jun 18; 125(1-2):86-95. PMID: 15193425.
      Citations:    
    100. Smothers CT, Woodward JJ, Smothers CT, Woodward JJ. Effect of the NR3 subunit on ethanol inhibition of recombinant NMDA receptors. Brain Res. 2003 Oct 10; 987(1):117-21. PMID: 14499953.
      Citations: 14     Fields:    Translation:Animals
    101. Woodward JJ, Smothers C, Woodward JJ, Smothers C. Ethanol inhibition of recombinant NR1/2A receptors: effects of heavy metal chelators and a zinc-insensitive NR2A mutant. Alcohol. 2003 Aug-Oct; 31(1-2):71-6. PMID: 14615013.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    102. Tillar R, Shafer TJ, Woodward JJ, Tillar R, Shafer TJ, Woodward JJ. Toluene inhibits voltage-sensitive calcium channels expressed in pheochromocytoma cells. Neurochem Int. 2002 Dec; 41(6):391-7. PMID: 12213226.
      Citations: 10     Fields:    Translation:AnimalsCells
    103. Bale AS, Smothers CT, Woodward JJ, Bale AS, Smothers CT, Woodward JJ. Inhibition of neuronal nicotinic acetylcholine receptors by the abused solvent, toluene. Br J Pharmacol. 2002 Oct; 137(3):375-83. PMID: 12237258; PMCID: PMC1573496.
      Citations: 16     Fields:    Translation:AnimalsCells
    104. Khaldi A, Chiueh CC, Bullock MR, Woodward JJ, Khaldi A, Chiueh CC, Bullock MR, Woodward JJ. The significance of nitric oxide production in the brain after injury. Ann N Y Acad Sci. 2002 May; 962:53-9. PMID: 12076962.
      Citations: 9     Fields:    Translation:HumansCells
    105. Chu DM, Woodward J, Fritzinger A, Marciano-Cabral F, Chu DM, Woodward J, Fritzinger A, Marciano-Cabral F. Calcium-dependent protection from complement lysis in Naegleria fowleri amebae. Cell Calcium. 2002 Mar; 31(3):105-14. PMID: 12027384.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    106. Khaldi A, Zauner A, Reinert M, Woodward JJ, Bullock MR, Khaldi A, Zauner A, Reinert M, Woodward JJ, Bullock MR. Measurement of nitric oxide and brain tissue oxygen tension in patients after severe subarachnoid hemorrhage. Neurosurgery. 2001 Jul; 49(1):33-8; discussion 38-40. PMID: 11440457.
      Citations: 12     Fields:    Translation:Humans
    107. Smothers CT, Clayton R, Blevins T, Woodward JJ, Smothers CT, Clayton R, Blevins T, Woodward JJ. Ethanol sensitivity of recombinant human N-methyl-D-aspartate receptors. Neurochem Int. 2001 Apr; 38(4):333-40. PMID: 11137628.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    108. Sun H, Subbotin V, Woodward J, Valdivia L, Fung JJ, Rao AS, Sun H, Subbotin V, Woodward J, Valdivia L, Fung JJ, Rao AS. Role of MHC class I and CD8(+) T cells in the pathogenesis of chronic rejection. Transplant Proc. 2001 Feb-Mar; 33(1-2):319. PMID: 11266839.
      Citations:    Fields:    Translation:AnimalsCells
    109. Cruz SL, Balster RL, Woodward JJ, Cruz SL, Balster RL, Woodward JJ. Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Br J Pharmacol. 2000 Dec; 131(7):1303-8. PMID: 11090101; PMCID: PMC1572451.
      Citations: 24     Fields:    Translation:AnimalsCells
    110. Spector M, Nguyen VA, Sheng X, He L, Woodward J, Fan S, Baumgarten CM, Kunos G, Dent P, Gao B, Spector M, Nguyen VA, Sheng X, He L, Woodward J, Fan S, Baumgarten CM, Kunos G, Dent P, Gao B. Activation of mitogen-activated protein kinases is required for alpha1-adrenergic agonist-induced cell scattering in transfected HepG2 cells. Exp Cell Res. 2000 Jul 10; 258(1):109-20. PMID: 10912793.
      Citations: 5     Fields:    Translation:HumansCells
    111. Anders DL, Blevins T, Smothers CT, Woodward JJ, Anders DL, Blevins T, Smothers CT, Woodward JJ. Reduced ethanol inhibition of N-methyl-D-aspartate receptors by deletion of the NR1 C0 domain or overexpression of alpha-actinin-2 proteins. J Biol Chem. 2000 May 19; 275(20):15019-24. PMID: 10809744.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    112. Clayton R, Woodward JJ, Clayton R, Woodward JJ. Effects of ethanol on three endogenous membrane conductances present in Xenopus laevis oocytes. Neurochem Int. 2000 Jan; 36(1):67-74. PMID: 10566960.
      Citations: 2     Fields:    Translation:AnimalsCells
    113. Woodward JJ, Woodward JJ. Ethanol and NMDA receptor signaling. Crit Rev Neurobiol. 2000; 14(1):69-89. PMID: 11253956.
      Citations: 58     Fields:    Translation:AnimalsCells
    114. Woodward JJ, Woodward JJ. Ionotropic glutamate receptors as sites of action for ethanol in the brain. Neurochem Int. 1999 Aug; 35(2):107-13. PMID: 10405994.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    115. Woodward JJ, Woodward JJ. Overview of the effects of alcohol on the cerebral nervous system. Neurochem Int. 1999 Aug; 35(2):93-4. PMID: 10405991.
      Citations: 3     Fields:    Translation:HumansAnimals
    116. Anders DL, Blevins T, Sutton G, Swope S, Chandler LJ, Woodward JJ, Anders DL, Blevins T, Sutton G, Swope S, Chandler LJ, Woodward JJ. Fyn tyrosine kinase reduces the ethanol inhibition of recombinant NR1/NR2A but not NR1/NR2B NMDA receptors expressed in HEK 293 cells. J Neurochem. 1999 Apr; 72(4):1389-93. PMID: 10098840.
      Citations: 15     Fields:    Translation:HumansCells
    117. Anders DL, Blevins T, Sutton G, Chandler LJ, Woodward JJ, Anders DL, Blevins T, Sutton G, Chandler LJ, Woodward JJ. Effects of c-Src tyrosine kinase on ethanol sensitivity of recombinant NMDA receptors expressed in HEK 293 cells. Alcohol Clin Exp Res. 1999 Feb; 23(2):357-62. PMID: 10069568.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    118. Alessandri B, Doppenberg E, Bullock R, Woodward J, Choi S, Koura S, Young HF, Alessandri B, Doppenberg E, Bullock R, Woodward J, Choi S, Koura S, Young HF. Glucose and lactate metabolism after severe human head injury: influence of excitatory neurotransmitters and injury type. Acta Neurochir Suppl. 1999; 75:21-4. PMID: 10635371.
      Citations: 5     Fields:    Translation:Humans
    119. Alessandri B, Doppenberg E, Zauner A, Woodward J, Choi S, Bullock R, Alessandri B, Doppenberg E, Zauner A, Woodward J, Choi S, Bullock R. Evidence for time-dependent glutamate-mediated glycolysis in head-injured patients: a microdialysis study. Acta Neurochir Suppl. 1999; 75:25-8. PMID: 10635372.
      Citations: 8     Fields:    Translation:HumansCells
    120. Bullock R, Zauner A, Woodward JJ, Myseros J, Choi SC, Ward JD, Marmarou A, Young HF, Bullock R, Zauner A, Woodward JJ, Myseros J, Choi SC, Ward JD, Marmarou A, Young HF. Factors affecting excitatory amino acid release following severe human head injury. J Neurosurg. 1998 Oct; 89(4):507-18. PMID: 9761042.
      Citations: 125     Fields:    Translation:HumansCells
    121. Mirshahi T, Anders DL, Ronald KM, Woodward JJ, Mirshahi T, Anders DL, Ronald KM, Woodward JJ. Intracellular calcium enhances the ethanol sensitivity of NMDA receptors through an interaction with the C0 domain of the NR1 subunit. J Neurochem. 1998 Sep; 71(3):1095-107. PMID: 9721734.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    122. Cruz SL, Mirshahi T, Thomas B, Balster RL, Woodward JJ, Cruz SL, Mirshahi T, Thomas B, Balster RL, Woodward JJ. Effects of the abused solvent toluene on recombinant N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther. 1998 Jul; 286(1):334-40. PMID: 9655877.
      Citations: 40     Fields:    Translation:AnimalsCells
    123. Doppenberg EM, Rice MR, Di X, Young HF, Woodward JJ, Bullock R, Doppenberg EM, Rice MR, Di X, Young HF, Woodward JJ, Bullock R. Increased free radical production due to subdural hematoma in the rat: effect of increased inspired oxygen fraction. J Neurotrauma. 1998 May; 15(5):337-47. PMID: 9605348.
      Citations: 7     Fields:    Translation:Animals
    124. Blevins T, Mirshahi T, Chandler LJ, Woodward JJ, Blevins T, Mirshahi T, Chandler LJ, Woodward JJ. Effects of acute and chronic ethanol exposure on heteromeric N-methyl-D-aspartate receptors expressed in HEK 293 cells. J Neurochem. 1997 Dec; 69(6):2345-54. PMID: 9375665.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    125. Zauner A, Doppenberg EM, Woodward JJ, Choi SC, Young HF, Bullock R, Zauner A, Doppenberg EM, Woodward JJ, Choi SC, Young HF, Bullock R. Continuous monitoring of cerebral substrate delivery and clearance: initial experience in 24 patients with severe acute brain injuries. Neurosurgery. 1997 Nov; 41(5):1082-91; discussion 1091-3. PMID: 9361062.
      Citations: 29     Fields:    Translation:Humans
    126. Zauner A, Doppenberg E, Woodward JJ, Allen C, Jebraili S, Young HF, Bullock R, Zauner A, Doppenberg E, Woodward JJ, Allen C, Jebraili S, Young HF, Bullock R. Multiparametric continuous monitoring of brain metabolism and substrate delivery in neurosurgical patients. Neurol Res. 1997 Jun; 19(3):265-73. PMID: 9192379.
      Citations: 14     Fields:    Translation:Humans
    127. Grasing K, Bills D, Ghosh S, Schlussman SD, Patel AH, Woodward JJ, Grasing K, Bills D, Ghosh S, Schlussman SD, Patel AH, Woodward JJ. Opiate modulation of striatal dopamine and hippocampal norepinephrine release following morphine withdrawal. Neurochem Res. 1997 Mar; 22(3):239-48. PMID: 9051656.
      Citations: 7     Fields:    Translation:Animals
    128. Moore KA, Mirshahi T, Compton DR, Poklis A, Woodward JJ, Moore KA, Mirshahi T, Compton DR, Poklis A, Woodward JJ. Pharmacological characterization of BNMPA (alpha-benzyl-N-methylphenethylamine), an impurity of illicit methamphetamine synthesis. Eur J Pharmacol. 1996 Sep 12; 311(2-3):133-9. PMID: 8891593.
      Citations: 1     Fields:    Translation:Animals
    129. Tsuchida E, Harms JF, Woodward JJ, Bullock R, Tsuchida E, Harms JF, Woodward JJ, Bullock R. A use-dependent sodium channel antagonist, 619C89, in reduction of ischemic brain damage and glutamate release after acute subdural hematoma in the rat. J Neurosurg. 1996 Jul; 85(1):104-11. PMID: 8683258.
      Citations: 2     Fields:    Translation:AnimalsCells
    130. Zauner A, Bullock R, Kuta AJ, Woodward J, Young HF, Zauner A, Bullock R, Kuta AJ, Woodward J, Young HF. Glutamate release and cerebral blood flow after severe human head injury. Acta Neurochir Suppl. 1996; 67:40-4. PMID: 8870800.
      Citations: 37     Fields:    Translation:Humans
    131. Blevins T, Mirshahi T, Woodward JJ, Blevins T, Mirshahi T, Woodward JJ. Increased agonist and antagonist sensitivity of N-methyl-D-aspartate stimulated calcium flux in cultured neurons following chronic ethanol exposure. Neurosci Lett. 1995 Nov 24; 200(3):214-8. PMID: 9064615.
      Citations: 10     Fields:    Translation:AnimalsCells
    132. Bullock R, Zauner A, Woodward J, Young HF, Bullock R, Zauner A, Woodward J, Young HF. Massive persistent release of excitatory amino acids following human occlusive stroke. Stroke. 1995 Nov; 26(11):2187-9. PMID: 7482671.
      Citations: 22     Fields:    Translation:Humans
    133. Bullock R, Zauner A, Myseros JS, Marmarou A, Woodward JJ, Young HF, Bullock R, Zauner A, Myseros JS, Marmarou A, Woodward JJ, Young HF. Evidence for prolonged release of excitatory amino acids in severe human head trauma. Relationship to clinical events. Ann N Y Acad Sci. 1995 Sep 15; 765:290-7; discussion 298. PMID: 7486616.
      Citations: 39     Fields:    Translation:Humans
    134. Stout AK, Woodward JJ, Stout AK, Woodward JJ. Mechanism for nitric oxide's enhancement of NMDA-stimulated [3H]norepinephrine release from rat hippocampal slices. Neuropharmacology. 1995 Jul; 34(7):723-9. PMID: 8532139.
      Citations: 1     Fields:    Translation:Animals
    135. Orr RK, Hoehn JL, Col NF, Lin J, Yon RW, Chavin KD, Qin L, Woodward J, Ding Y, Yagita H, Bromberg JS. Anti-CD2 monoclonal antibody-induced receptor changes: down modulation of cell surface CD2. Transplantation. 1995 Apr 27; 59(8):1162-71. PMID: 7537394.
      Citations:    Fields:    Translation:AnimalsCells
    136. Woodward JJ, Compton DM, Balster RL, Martin BR, Woodward JJ, Compton DM, Balster RL, Martin BR. In vitro and in vivo effects of cocaine and selected local anesthetics on the dopamine transporter. Eur J Pharmacol. 1995 Apr 13; 277(1):7-13. PMID: 7635175.
      Citations: 11     Fields:    Translation:AnimalsCells
    137. Mirshahi T, Woodward JJ, Mirshahi T, Woodward JJ. Ethanol sensitivity of heteromeric NMDA receptors: effects of subunit assembly, glycine and NMDAR1 Mg(2+)-insensitive mutants. Neuropharmacology. 1995 Mar; 34(3):347-55. PMID: 7630488.
      Citations: 45     Fields:    Translation:AnimalsCells
    138. Baliga P, Chavin KD, Qin L, Woodward J, Lin J, Linsley PS, Bromberg JS, Baliga P, Chavin KD, Qin L, Woodward J, Lin J, Linsley PS, Bromberg JS. CTLA4Ig prolongs allograft survival while suppressing cell-mediated immunity. Transplantation. 1994 Nov 27; 58(10):1082-90. PMID: 7526493.
      Citations: 22     Fields:    Translation:AnimalsCells
    139. Stout AK, Woodward JJ, Stout AK, Woodward JJ. Differential effects of nitric oxide gas and nitric oxide donors on depolarization-induced release of [3H]norepinephrine from rat hippocampal slices. Neuropharmacology. 1994 Nov; 33(11):1367-74. PMID: 7532819.
      Citations: 3     Fields:    Translation:AnimalsCells
    140. Chavin KD, Qin L, Lin J, Woodward J, Baliga P, Kato K, Yagita H, Bromberg JS, Chavin KD, Qin L, Lin J, Woodward J, Baliga P, Kato K, Yagita H, Bromberg JS. Anti-CD48 (murine CD2 ligand) mAbs suppress cell mediated immunity in vivo. Int Immunol. 1994 May; 6(5):701-9. PMID: 7521667.
      Citations: 10     Fields:    Translation:AnimalsCells
    141. Woodward JJ, Woodward JJ. The effects of thiol reduction and oxidation on the inhibition of NMDA-stimulated neurotransmitter release by ethanol. Neuropharmacology. 1994 May; 33(5):635-40. PMID: 7936098.
      Citations: 1     Fields:    Translation:AnimalsCells
    142. Woodward JJ, Woodward JJ. A comparison of the effects of ethanol and the competitive glycine antagonist 7-chlorokynurenic acid on N-methyl-D-aspartic acid-induced neurotransmitter release from rat hippocampal slices. J Neurochem. 1994 Mar; 62(3):987-91. PMID: 7906723.
      Citations: 4     Fields:    Translation:Animals
    143. Mandel RJ, Hartgraves SL, Severson JA, Woodward JJ, Wilcox RE, Randall PK, Mandel RJ, Hartgraves SL, Severson JA, Woodward JJ, Wilcox RE, Randall PK. A quantitative estimate of the role of striatal D-2 receptor proliferation in dopaminergic behavioral supersensitivity: the contribution of mesolimbic dopamine to the magnitude of 6-OHDA lesion-induced agonist sensitivity in the rat. Behav Brain Res. 1993 Dec 31; 59(1-2):53-64. PMID: 8155293.
      Citations: 8     Fields:    Translation:Animals
    144. Woodward JJ, Cueto S, Woodward JJ, Cueto S. Effects of the putative polyamine antagonists diethylenetriamine and 1,10-diaminodecane on N-methyl-D-aspartic acid-stimulated [3H]norepinephrine release from rat hippocampal slices. J Pharmacol Exp Ther. 1993 Aug; 266(2):563-9. PMID: 8355191.
      Citations:    Fields:    Translation:Animals
    145. Woodward JJ, Harms J, Woodward JJ, Harms J. Potentiation of N-methyl-D-aspartate-stimulated dopamine release from rat brain slices by aluminum fluoride and carbachol. J Neurochem. 1992 Apr; 58(4):1547-54. PMID: 1532197.
      Citations: 2     Fields:    Translation:Animals
    146. Woodward JJ, Harms J, Woodward JJ, Harms J. The putative polyamine antagonists ifenprodil and SL 82.0715 enhance dopamine efflux from rat striatal slices independent of NMDA receptor activation. Eur J Pharmacol. 1992 Jan 21; 210(3):265-70. PMID: 1351843.
      Citations: 1     Fields:    Translation:Animals
    147. Woodward JJ, Blair R, Woodward JJ, Blair R. Redox modulation of N-methyl-D-aspartate-stimulated neurotransmitter release from rat brain slices. J Neurochem. 1991 Dec; 57(6):2059-64. PMID: 1682419.
      Citations: 3     Fields:    Translation:AnimalsCells
    148. Woodward JJ, Mansbach R, Carroll FI, Balster RL, Woodward JJ, Mansbach R, Carroll FI, Balster RL. Cocaethylene inhibits dopamine uptake and produces cocaine-like actions in drug discrimination studies. Eur J Pharmacol. 1991 May 17; 197(2-3):235-6. PMID: 1915572.
      Citations: 8     Fields:    Translation:Animals
    149. Woodward JJ, Brown L, Gonzales RA, Woodward JJ, Brown L, Gonzales RA. Modulation of ethanol-induced inhibition of N-methyl-D-aspartate-stimulated neurotransmitter release by glycine. Alcohol Alcohol Suppl. 1991; 1:177-80. PMID: 1845534.
      Citations: 1     Fields:    Translation:Animals
    150. Wilcox RE, Severson JA, Woodward JJ, Randall PK, Vaughn DM, Riffee WH, Wilcox RE, Severson JA, Woodward JJ, Randall PK, Vaughn DM, Riffee WH. Behavioral sensitization following a single apomorphine pretreatment--selective effects on the dopamine release process. Brain Res. 1990 Sep 24; 528(1):109-13. PMID: 2147118.
      Citations: 1     Fields:    Translation:Animals
    151. Vaughn DM, Severson JA, Woodward JJ, Randall PK, Riffee WH, Leslie SW, Wilcox RE, Vaughn DM, Severson JA, Woodward JJ, Randall PK, Riffee WH, Leslie SW, Wilcox RE. Behavioral sensitization following subchronic apomorphine treatment--possible neurochemical basis. Brain Res. 1990 Aug 27; 526(1):37-44. PMID: 2150341.
      Citations: 3     Fields:    Translation:Animals
    152. Woodward JJ, Machu T, Leslie SW, Woodward JJ, Machu T, Leslie SW. Chronic ethanol treatment alters omega-conotoxin and Bay K 8644 sensitive calcium channels in rat striatal synaptosomes. Alcohol. 1990 Jul-Aug; 7(4):279-84. PMID: 1697172.
      Citations: 3     Fields:    Translation:AnimalsCells
    153. Gonzales RA, Woodward JJ, Gonzales RA, Woodward JJ. Ethanol inhibits N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat cortical slices. J Pharmacol Exp Ther. 1990 Jun; 253(3):1138-44. PMID: 2162947.
      Citations: 17     Fields:    Translation:Animals
    154. Woodward JJ, Gonzales RA, Woodward JJ, Gonzales RA. Ethanol inhibition of N-methyl-D-aspartate-stimulated endogenous dopamine release from rat striatal slices: reversal by glycine. J Neurochem. 1990 Feb; 54(2):712-5. PMID: 2405104.
      Citations: 17     Fields:    Translation:Animals
    155. Machu T, Woodward JJ, Leslie SW, Machu T, Woodward JJ, Leslie SW. Ethanol and inositol 1,4,5-trisphosphate mobilize calcium from rat brain microsomes. Alcohol. 1989 Nov-Dec; 6(6):431-6. PMID: 2597345.
      Citations: 2     Fields:    Translation:AnimalsCells
    156. Rezazadeh SM, Woodward JJ, Leslie SW, Rezazadeh SM, Woodward JJ, Leslie SW. Fura-2 measurement of cytosolic free calcium in rat brain cortical synaptosomes and the influence of ethanol. Alcohol. 1989 Sep-Oct; 6(5):341-5. PMID: 2818835.
      Citations: 4     Fields:    Translation:AnimalsCells
    157. Woodward JJ, Leslie SW, Severson JA, Wilcox RE, Woodward JJ, Leslie SW, Severson JA, Wilcox RE. Aging does not alter the voltage-dependent release of endogenous dopamine from mouse striatal synaptosomes. Neurosci Lett. 1989 Feb 13; 97(1-2):191-7. PMID: 2919003.
      Citations: 2     Fields:    Translation:AnimalsCells
    158. Woodward JJ, Rezazadeh SM, Leslie SW, Woodward JJ, Rezazadeh SM, Leslie SW. Differential sensitivity of synaptosomal calcium entry and endogenous dopamine release to omega-conotoxin. Brain Res. 1988 Dec 13; 475(1):141-5. PMID: 3214720.
      Citations: 7     Fields:    Translation:AnimalsCells
    159. Woodward JJ, Chandler LJ, Leslie SW, Woodward JJ, Chandler LJ, Leslie SW. Calcium-dependent and -independent release of endogenous dopamine from rat striatal synaptosomes. Brain Res. 1988 Nov 08; 473(1):91-8. PMID: 3208129.
      Citations: 5     Fields:    Translation:AnimalsCells
    160. Woodward JJ, Cook ME, Leslie SW, Woodward JJ, Cook ME, Leslie SW. Characterization of dihydropyridine-sensitive calcium channels in rat brain synaptosomes. Proc Natl Acad Sci U S A. 1988 Oct; 85(19):7389-93. PMID: 2459704; PMCID: PMC282192.
      Citations: 3     Fields:    Translation:AnimalsCells
    161. Giulian D, Woodward J, Young DG, Krebs JF, Lachman LB, Giulian D, Woodward J, Young DG, Krebs JF, Lachman LB. Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization. J Neurosci. 1988 Jul; 8(7):2485-90. PMID: 2470873; PMCID: PMC6569517.
      Citations: 94     Fields:    Translation:Animals
    162. Woodward JJ, Wilcox RE, Leslie SW, Riffee WH, Woodward JJ, Wilcox RE, Leslie SW, Riffee WH. Dopamine uptake during fast-phase endogenous dopamine release from mouse striatal synaptosomes. Neurosci Lett. 1986 Oct 30; 71(1):106-12. PMID: 3785732.
      Citations: 4     Fields:    Translation:AnimalsCells
    163. Severson JA, Woodward JJ, Wilcox RE, Severson JA, Woodward JJ, Wilcox RE. Subdivision of mouse brain [3H]imipramine binding based on ion dependence and serotonin sensitivity. J Neurochem. 1986 Jun; 46(6):1743-54. PMID: 3701330.
      Citations: 2     Fields:    Translation:AnimalsCells
    164. Woodward JJ, Leslie SW, Woodward JJ, Leslie SW. Bay K 8644 stimulation of calcium entry and endogenous dopamine release in rat striatal synaptosomes antagonized by nimodipine. Brain Res. 1986 Apr 09; 370(2):397-400. PMID: 2423182.
      Citations: 12     Fields:    Translation:AnimalsCells
    165. Leslie SW, Woodward JJ, Wilcox RE, Farrar RP, Leslie SW, Woodward JJ, Wilcox RE, Farrar RP. Chronic ethanol treatment uncouples striatal calcium entry and endogenous dopamine release. Brain Res. 1986 Mar 12; 368(1):174-7. PMID: 3955358.
      Citations: 2     Fields:    Translation:AnimalsCells
    166. Leslie SW, Woodward JJ, Wilcox RE, Leslie SW, Woodward JJ, Wilcox RE. Correlation of rates of calcium entry and endogenous dopamine release in mouse striatal synaptosomes. Brain Res. 1985 Jan 28; 325(1-2):99-105. PMID: 2983836.
      Citations: 10     Fields:    Translation:AnimalsCells
    167. Casillas E, Smith LS, Woodward JJ, D'Aoust BG, Casillas E, Smith LS, Woodward JJ, D'Aoust BG. Hematologic response of fish to changes in gas or hydrostatic pressure. Am J Physiol. 1980 Jul; 239(1):R161-7. PMID: 7396032.
      Citations:    Fields:    Translation:AnimalsCells
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