"Neuropilin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
| Descriptor ID |
D039942
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| MeSH Number(s) |
D12.776.543.750.590.500
|
| Concept/Terms |
Neuropilin-1- Neuropilin-1
- Neuropilin 1
- Sema III Receptor
- Receptor, Sema III
- NRP1 Protein
- Semaphorin III Receptor
- A5 Antigen
- Antigen, A5
- Npn-1 Protein
- Npn 1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Neuropilin-1".
Below are MeSH descriptors whose meaning is more specific than "Neuropilin-1".
This graph shows the total number of publications written about "Neuropilin-1" by people in this website by year, and whether "Neuropilin-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Neuropilin-1" by people in Profiles.
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Dhupar R, Jones KE, Powers AA, Eisenberg SH, Ding K, Chen F, Nasarre C, Cen Z, Gong YN, LaRue AC, Yeh ES, Luketich JD, Lee AV, Oesterreich S, Lotze MT, Gemmill RM, Soloff AC. Isoforms of Neuropilin-2 Denote Unique Tumor-Associated Macrophages in Breast Cancer. Front Immunol. 2022; 13:830169.
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Nasarre P, Kusy S, Constantin B, Castellani V, Drabkin HA, Bagnard D, Roche J. Semaphorin SEMA3F has a repulsing activity on breast cancer cells and inhibits E-cadherin-mediated cell adhesion. Neoplasia. 2005 Feb; 7(2):180-9.
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Nasarre P, Constantin B, Rouhaud L, Harnois T, Raymond G, Drabkin HA, Bourmeyster N, Roche J. Semaphorin SEMA3F and VEGF have opposing effects on cell attachment and spreading. Neoplasia. 2003 Jan-Feb; 5(1):83-92.