Bleomycin

"Bleomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.

Descriptor ID	D001761
MeSH Number(s)	D09.400.420.110 D12.644.233.110
Concept/Terms	Bleomycin Bleomycin Bleomycins BLEO-cell BLEO-cell BLEO cell BLEOcell Bleolem Bleolem Bléomycine Bellon Bléomycine Bellon Bellon, Bléomycine Bleomycin A2 Bleomycin A2 Bleomycin A(2) Bleomycin B2 Bleomycin B2 Bleomycin B(2) Bleomycin Sulfate Bleomycin Sulfate Sulfate, Bleomycin Bleomycinum Mack Bleomycinum Mack Mack, Bleomycinum Blenoxane Blenoxane Blanoxan Bleomicina Bleomicina

Below are MeSH descriptors whose meaning is more general than "Bleomycin".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Glycopeptides [D09.400.420]
Bleomycin [D09.400.420.110]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Glycopeptides [D12.644.233]
Bleomycin [D12.644.233.110]

Below are MeSH descriptors whose meaning is related to "Bleomycin".

Below are MeSH descriptors whose meaning is more specific than "Bleomycin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Bleomycin" by people in this website by year, and whether "Bleomycin" was a major or minor topic of these publications.

Bar chart showing 44 publications over 20 distinct years, with a maximum of 6 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	0	1
2002	0	1	1
2003	1	1	2
2004	0	3	3
2005	0	1	1
2006	0	1	1
2007	0	1	1
2008	0	2	2
2010	0	1	1
2011	0	2	2
2012	0	3	3
2013	1	5	6
2014	1	0	1
2015	0	2	2
2016	0	2	2
2017	0	3	3
2018	0	1	1
2019	1	3	4
2020	0	5	5
2022	0	2	2

Below are the most recent publications written about "Bleomycin" by people in Profiles.

Reese CF, Chinnakkannu P, Tourkina E, Hoffman S, Kuppuswamy D. Multiple subregions within the caveolin-1 scaffolding domain inhibit fibrosis, microvascular leakage, and monocyte migration. PLoS One. 2022; 17(2):e0264413.

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Hung CF, Wilson CL, Chow YH, Liles WC, Gharib SA, Altemeier WA, Schnapp LM. Effect of lung pericyte-like cell ablation on the bleomycin model of injury and repair. Am J Physiol Lung Cell Mol Physiol. 2022 04 01; 322(4):L607-L616.

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Nguyen XX, Sanderson M, Helke K, Feghali-Bostwick C. Phenotypic Characterization of Transgenic Mice Expressing Human IGFBP-5. Int J Mol Sci. 2020 Dec 30; 22(1).

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Nguyen XX, Nishimoto T, Takihara T, Mlakar L, Bradshaw AD, Feghali-Bostwick C. Lysyl oxidase directly contributes to extracellular matrix production and fibrosis in systemic sclerosis. Am J Physiol Lung Cell Mol Physiol. 2021 01 01; 320(1):L29-L40.

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Herro R, Miki H, Sethi GS, Mills D, Mehta AK, Nguyen XX, Feghali-Bostwick C, Miller M, Broide DH, Soloff R, Croft M. TL1A Promotes Lung Tissue Fibrosis and Airway Remodeling. J Immunol. 2020 11 01; 205(9):2414-2422.

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Chirivi RGS, van Rosmalen JWG, van der Linden M, Euler M, Schmets G, Bogatkevich G, Kambas K, Hahn J, Braster Q, Soehnlein O, Hoffmann MH, Es HHGV, Raats JMH. Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases. Cell Mol Immunol. 2021 06; 18(6):1528-1544.

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Nanri Y, Nunomura S, Terasaki Y, Yoshihara T, Hirano Y, Yokosaki Y, Yamaguchi Y, Feghali-Bostwick C, Ajito K, Murakami S, Conway SJ, Izuhara K. Cross-Talk between Transforming Growth Factor-ß and Periostin Can Be Targeted for Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2020 02; 62(2):204-216.

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Schniering J, Benešová M, Brunner M, Haller S, Cohrs S, Frauenfelder T, Vrugt B, Feghali-Bostwick C, Schibli R, Distler O, Müller C, Maurer B. 18F-AzaFol for Detection of Folate Receptor-ß Positive Macrophages in Experimental Interstitial Lung Disease-A Proof-of-Concept Study. Front Immunol. 2019; 10:2724.

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Sellares J, Veraldi KL, Thiel KJ, Cárdenes N, Alvarez D, Schneider F, Pilewski JM, Rojas M, Feghali-Bostwick CA. Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2019 06; 60(6):629-636.

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Suryadevara V, Huang L, Kim SJ, Cheresh P, Shaaya M, Bandela M, Fu P, Feghali-Bostwick C, Di Paolo G, Kamp DW, Natarajan V. Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2019 08 01; 317(2):L175-L187.

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