"Ryanodine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
| Descriptor ID |
D012433
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| MeSH Number(s) |
D02.455.849.291.686 D03.132.740 D03.383.129.578.805
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ryanodine".
Below are MeSH descriptors whose meaning is more specific than "Ryanodine".
This graph shows the total number of publications written about "Ryanodine" by people in this website by year, and whether "Ryanodine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ryanodine" by people in Profiles.
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Developmental aspects of cardiac Ca(2+) signaling: interplay between RyR- and IP(3)R-gated Ca(2+) stores. Am J Physiol Heart Circ Physiol. 2010 Jun; 298(6):H1939-50.
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Multi-minicore disease and atypical periodic paralysis associated with novel mutations in the skeletal muscle ryanodine receptor (RYR1) gene. Neuromuscul Disord. 2010 Mar; 20(3):166-73.
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Diversity of atrial local Ca2+ signalling: evidence from 2-D confocal imaging in Ca2+-buffered rat atrial myocytes. J Physiol. 2005 Sep 15; 567(Pt 3):905-21.
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Clinical and functional effects of a deletion in a COOH-terminal lumenal loop of the skeletal muscle ryanodine receptor. Hum Mol Genet. 2003 Feb 15; 12(4):379-88.
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Spatiotemporal characteristics of junctional and nonjunctional focal Ca2+ release in rat atrial myocytes. Circ Res. 2003 Jan 10; 92(1):e1-11.
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Focal sarcoplasmic reticulum calcium stores and diffuse inositol 1,4,5-trisphosphate and ryanodine receptors in human myometrium. Cell Calcium. 1999 Jul-Aug; 26(1-2):69-75.
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Effect of internal sodium and cellular calcium load on voltage-dependence of the Indo-1 transient in guinea-pig ventricular myocytes. Cardiovasc Res. 1996 Sep; 32(3):534-50.