"Pyrrolizidine Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
Descriptor ID |
D011763
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MeSH Number(s) |
D03.132.716 D03.633.100.772
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pyrrolizidine Alkaloids".
Below are MeSH descriptors whose meaning is more specific than "Pyrrolizidine Alkaloids".
This graph shows the total number of publications written about "Pyrrolizidine Alkaloids" by people in this website by year, and whether "Pyrrolizidine Alkaloids" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 2 | 2 |
2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyrrolizidine Alkaloids" by people in Profiles.
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Synthesis of (-)-(R)-pyrrolam a and studies on its stability: a caveat on computational methods. J Org Chem. 2004 Sep 03; 69(18):6105-14.
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Comparison of two ammoniation procedures to reduce the toxicity of endophyte-infected tall fescue seed fed to rats. Drug Chem Toxicol. 1998 Aug; 21(3):387-404.
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Comparison of two ammoniation procedures to reduce the toxicity of endophyte-infected tall fescue seed fed to rats. Drug Chem Toxicol. 1998 Feb; 21(1):79-95.
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Enhanced activity of the cardiac endocrine system during right ventricular hypertrophy. Mol Cell Endocrinol. 1989 Apr; 62(2):243-51.
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Stability-indicating colorimetric assay for indicine N-oxide using TLC. J Pharm Sci. 1980 Apr; 69(4):471-2.