Kynurenic Acid

"Kynurenic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A broad-spectrum excitatory amino acid antagonist used as a research tool.

Descriptor ID	D007736
MeSH Number(s)	D03.066.942.505 D03.633.100.810.350.400
Concept/Terms	Kynurenic Acid Kynurenic Acid Acid, Kynurenic Kynurenate Kynurenate

Below are MeSH descriptors whose meaning is more general than "Kynurenic Acid".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Acids, Heterocyclic [D03.066]
Xanthurenates [D03.066.942]
Kynurenic Acid [D03.066.942.505]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Quinolines [D03.633.100.810]
Hydroxyquinolines [D03.633.100.810.350]
Kynurenic Acid [D03.633.100.810.350.400]

Below are MeSH descriptors whose meaning is related to "Kynurenic Acid".

Below are MeSH descriptors whose meaning is more specific than "Kynurenic Acid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Kynurenic Acid" by people in this website by year, and whether "Kynurenic Acid" was a major or minor topic of these publications.

Bar chart showing 24 publications over 15 distinct years, with a maximum of 5 publications in 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1996	0	1	1
1997	0	1	1
2001	1	0	1
2007	0	1	1
2009	0	1	1
2011	1	1	2
2012	0	1	1
2013	1	0	1
2014	1	2	3
2016	0	2	2
2017	1	1	2
2018	4	1	5
2020	1	0	1
2021	1	0	1

Below are the most recent publications written about "Kynurenic Acid" by people in Profiles.

Rentschler KM, Baratta AM, Ditty AL, Wagner NTJ, Wright CJ, Milosavljevic S, Mong JA, Pocivavsek A. Prenatal Kynurenine Elevation Elicits Sex-Dependent Changes in Sleep and Arousal During Adulthood: Implications for Psychotic Disorders. Schizophr Bull. 2021 08 21; 47(5):1320-1330.

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Friendshuh CR, Pocivavsek A, Demyonovich H, Rodriguez KM, Cihakova D, Talor MV, Richardson CM, Vyas G, Adams HA, Baratta AB, Fasano A, Cascella N, Feldman S, Liu F, Sayer M, Powell MM, Wehring HJ, Buchanan RW, Carpenter WT, Eaton WW, Kelly DL. The Effects of a Gluten-Free Diet on Immune Markers and Kynurenic Acid Pathway Metabolites in Patients With Schizophrenia Positive for Antigliadin Antibodies Immunoglobulin G. J Clin Psychopharmacol. 2020 May/Jun; 40(3):317-319.

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Baratta AM, Viechweg SS, Mong JA, Pocivavsek A. A High-performance Liquid Chromatography Measurement of Kynurenine and Kynurenic Acid: Relating Biochemistry to Cognition and Sleep in Rats. J Vis Exp. 2018 08 19; (138).

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Baratta AM, Buck SA, Buchla AD, Fabian CB, Chen S, Mong JA, Pocivavsek A. Sex Differences in Hippocampal Memory and Kynurenic Acid Formation Following Acute Sleep Deprivation in Rats. Sci Rep. 2018 05 03; 8(1):6963.

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Armenta-Resendiz M, Cruz SL, Galván EJ. Repeated toluene exposure increases the excitability of layer 5 pyramidal neurons in the prefrontal cortex of adolescent rats. Neurotoxicol Teratol. 2018 Jul - Aug; 68:27-35.

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Chiappelli J, Rowland LM, Notarangelo FM, Wijtenburg SA, Thomas MAR, Pocivavsek A, Jones A, Wisner K, Kochunov P, Schwarcz R, Hong LE. Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia. Neuropsychopharmacology. 2018 07; 43(8):1706-1711.

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Chiappelli J, Notarangelo FM, Pocivavsek A, Thomas MAR, Rowland LM, Schwarcz R, Hong LE. Influence of plasma cytokines on kynurenine and kynurenic acid in schizophrenia. Neuropsychopharmacology. 2018 07; 43(8):1675-1680.

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Pocivavsek A, Baratta AM, Mong JA, Viechweg SS. Acute Kynurenine Challenge Disrupts Sleep-Wake Architecture and Impairs Contextual Memory in Adult Rats. Sleep. 2017 11 01; 40(11).

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Goeden N, Notarangelo FM, Pocivavsek A, Beggiato S, Bonnin A, Schwarcz R. Prenatal Dynamics of Kynurenine Pathway Metabolism in Mice: Focus on Kynurenic Acid. Dev Neurosci. 2017; 39(6):519-528.

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Erhardt S, Pocivavsek A, Repici M, Liu XC, Imbeault S, Maddison DC, Thomas MAR, Smalley JL, Larsson MK, Muchowski PJ, Giorgini F, Schwarcz R. Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders. Biol Psychiatry. 2017 Nov 15; 82(10):756-765.

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