Epoxide Hydrolases

"Epoxide Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that catalyze reversibly the formation of an epoxide or arene oxide from a glycol or aromatic diol, respectively.

Descriptor ID	D004851
MeSH Number(s)	D08.811.277.340
Concept/Terms	Epoxide Hydrolases Epoxide Hydrolases Hydrolases, Epoxide Epoxide Hydratases Hydratases, Epoxide Epoxide Hydrases Hydrases, Epoxide Microsomal Epoxide Hydrolase Microsomal Epoxide Hydrolase Epoxide Hydrolase, Microsomal Hydrolase, Microsomal Epoxide Styrene Epoxide Hydrolase Styrene Epoxide Hydrolase Epoxide Hydrolase, Styrene Hydrolase, Styrene Epoxide 9,10-Epoxypalmitic Acid Hydrase 9,10-Epoxypalmitic Acid Hydrase 9,10 Epoxypalmitic Acid Hydrase Acid Hydrase, 9,10-Epoxypalmitic Hydrase, 9,10-Epoxypalmitic Acid

Below are MeSH descriptors whose meaning is more general than "Epoxide Hydrolases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Epoxide Hydrolases [D08.811.277.340]

Below are MeSH descriptors whose meaning is related to "Epoxide Hydrolases".

Below are MeSH descriptors whose meaning is more specific than "Epoxide Hydrolases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Epoxide Hydrolases" by people in this website by year, and whether "Epoxide Hydrolases" was a major or minor topic of these publications.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 3 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
2003	1	0	1
2007	1	0	1
2008	3	0	3
2011	0	1	1
2020	0	1	1

Below are the most recent publications written about "Epoxide Hydrolases" by people in Profiles.

Grapov D, Fiehn O, Campbell C, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Keim NL, Hunter GR, Fernandez JR, Garvey WT, Hoppel CL, Harper ME, Newman JW, Adams SH. Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women. Physiol Rep. 2020 09; 8(17):e14547.

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Wang J, Joshi AD, Corral R, Siegmund KD, Marchand LL, Martinez ME, Haile RW, Ahnen DJ, Sandler RS, Lance P, Stern MC. Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk. Int J Cancer. 2012 Apr 15; 130(8):1898-907.

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Ye B, Bauman J, Chen M, Davey D, Khim SK, King B, Kirkland T, Kochanny M, Liang A, Lentz D, May K, Mendoza L, Phillips G, Selchau V, Schlyer S, Tseng JL, Wei RG, Ye H, Parkinson J, Guilford WJ. Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase. Bioorg Med Chem Lett. 2008 Jul 15; 18(14):3891-4.

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Khim SK, Bauman J, Evans J, Freeman B, King B, Kirkland T, Kochanny M, Lentz D, Liang A, Mendoza L, Phillips G, Tseng JL, Wei RG, Ye H, Yu L, Parkinson J, Guilford WJ. Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors. Bioorg Med Chem Lett. 2008 Jul 15; 18(14):3895-8.

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Kirkland TA, Adler M, Bauman JG, Chen M, Haeggström JZ, King B, Kochanny MJ, Liang AM, Mendoza L, Phillips GB, Thunnissen M, Trinh L, Whitlow M, Ye B, Ye H, Parkinson J, Guilford WJ. Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase. Bioorg Med Chem. 2008 May 01; 16(9):4963-83.

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Vibhuti A, Arif E, Deepak D, Singh B, Qadar Pasha MA. Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD. Biochem Biophys Res Commun. 2007 Jul 20; 359(1):136-42.

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DuBois RN. Leukotriene A4 signaling, inflammation, and cancer. J Natl Cancer Inst. 2003 Jul 16; 95(14):1028-9.

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Pahan K, Smith BT, Singh I. Epoxide hydrolase in human and rat peroxisomes: implication for disorders of peroxisomal biogenesis. J Lipid Res. 1996 Jan; 37(1):159-67.

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