"Peptide Hydrolases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES.
| Descriptor ID |
D010447
|
| MeSH Number(s) |
D08.811.277.656
|
| Concept/Terms |
Peptide Hydrolases- Peptide Hydrolases
- Proteolytic Enzymes
- Proteases
- Proteinases
- Esteroproteases
- Peptidases
|
Below are MeSH descriptors whose meaning is more general than "Peptide Hydrolases".
Below are MeSH descriptors whose meaning is more specific than "Peptide Hydrolases".
This graph shows the total number of publications written about "Peptide Hydrolases" by people in this website by year, and whether "Peptide Hydrolases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 3 | 4 |
| 2007 | 2 | 0 | 2 |
| 2008 | 2 | 2 | 4 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 3 | 3 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 3 | 4 |
| 2023 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Peptide Hydrolases" by people in Profiles.
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Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease. Methods Mol Biol. 2023; 2591:171-188.
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The human pathobiont Malassezia furfur secreted protease Mfsap1 regulates cell dispersal and exacerbates skin inflammation. Proc Natl Acad Sci U S A. 2022 12 06; 119(49):e2212533119.
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Characterization of TR-107, a novel chemical activator of the human mitochondrial protease ClpP. Pharmacol Res Perspect. 2022 08; 10(4):e00993.
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IGF-dependent dynamic modulation of a protease cleavage site in the intrinsically disordered linker domain of human IGFBP2. Proteins. 2022 09; 90(9):1732-1743.
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Correlational networking guides the discovery of unclustered lanthipeptide protease-encoding genes. Nat Commun. 2022 03 28; 13(1):1647.
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Protease-dependent defects in N-cadherin processing drive PMM2-CDG pathogenesis. JCI Insight. 2021 12 22; 6(24).
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A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease. Cell Rep. 2021 09 28; 36(13):109754.
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Identification of Malassezia furfur Secreted Aspartyl Protease 1 (MfSAP1) and Its Role in Extracellular Matrix Degradation. Front Cell Infect Microbiol. 2020; 10:148.
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Pan-PIM kinase inhibitors enhance Lenalidomide's anti-myeloma activity via cereblon-IKZF1/3 cascade. Cancer Lett. 2019 01; 440-441:1-10.
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TAILS proteomics reveals dynamic changes in airway proteolysis controlling protease activity and innate immunity during COPD exacerbations. Am J Physiol Lung Cell Mol Physiol. 2018 12 01; 315(6):L1003-L1014.