"Ghrelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.
| Descriptor ID |
D054439
|
| MeSH Number(s) |
D06.472.699.301 D12.644.548.322
|
| Concept/Terms |
GHRL Protein- GHRL Protein
- Ppghrelin
- Ghrelin-Obestatin Preprohormone
- Ghrelin Obestatin Preprohormone
- Motilin-Related Peptide Precursor
- Motilin Related Peptide Precursor
- Peptide Precursor, Motilin-Related
- Precursor, Motilin-Related Peptide
- PpMTLRP
- Ghrelin Precursor
- Precursor, Ghrelin
Appetite-Regulating Hormone- Appetite-Regulating Hormone
- Appetite Regulating Hormone
- Motilin-Related Peptide
- Motilin Related Peptide
- Gastric MLTRP
|
Below are MeSH descriptors whose meaning is more general than "Ghrelin".
Below are MeSH descriptors whose meaning is more specific than "Ghrelin".
This graph shows the total number of publications written about "Ghrelin" by people in this website by year, and whether "Ghrelin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ghrelin" by people in Profiles.
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Liraglutide reduces oxidative stress and restores heme oxygenase-1 and ghrelin levels in patients with type 2 diabetes: a prospective pilot study. J Clin Endocrinol Metab. 2015 Feb; 100(2):603-6.
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A review of the cardiovascular and anti-atherogenic effects of ghrelin. Curr Pharm Des. 2013; 19(27):4953-63.
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Acute satiety response of mammalian, avian and fish proteins in dogs. Br J Nutr. 2012 Jan; 107(1):146-54.
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Serum ghrelin is inversely associated with cognitive function in a sample of non-demented elderly. Psychiatry Clin Neurosci. 2010 Dec; 64(6):608-11.
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Increased ghrelin sensitivity and calorie consumption in subordinate monkeys is affected by short-term astressin B administration. Endocrine. 2010 Oct; 38(2):227-34.
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Comparison of maternal ghrelin and leptin in healthy mothers and mothers with Type 1 diabetes. Diabet Med. 2008 Dec; 25(12):1400-5.
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Estrogen elevates the peak overnight production rate of acylated ghrelin. J Clin Endocrinol Metab. 2008 Nov; 93(11):4440-7.
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Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women. J Clin Endocrinol Metab. 2008 Oct; 93(10):4020-6.
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Ciprofloxacin suppresses bacterial overgrowth, increases fasting insulin but does not correct low acylated ghrelin concentration in non-alcoholic steatohepatitis. Aliment Pharmacol Ther. 2005 Aug 15; 22(4):291-9.
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Increased fasting plasma ghrelin levels during alcohol abstinence. Alcohol Alcohol. 2005 Jan-Feb; 40(1):76-9.