CpG Islands

"CpG Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.

Descriptor ID	D018899
MeSH Number(s)	G02.111.570.080.380.160 G05.360.080.380.160 G05.360.340.024.159
Concept/Terms	CpG Islands CpG Islands CpG Island Island, CpG Islands, CpG CpG-Rich Islands CpG Rich Islands CpG-Rich Island Island, CpG-Rich Islands, CpG-Rich CpG Clusters CpG Clusters Cluster, CpG Clusters, CpG CpG Cluster

Below are MeSH descriptors whose meaning is more general than "CpG Islands".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Base Sequence [G02.111.570.080]
GC Rich Sequence [G02.111.570.080.380]
CpG Islands [G02.111.570.080.380.160]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Base Sequence [G05.360.080]
GC Rich Sequence [G05.360.080.380]
CpG Islands [G05.360.080.380.160]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
CpG Islands [G05.360.340.024.159]

Below are MeSH descriptors whose meaning is related to "CpG Islands".

Below are MeSH descriptors whose meaning is more specific than "CpG Islands".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CpG Islands" by people in this website by year, and whether "CpG Islands" was a major or minor topic of these publications.

Bar chart showing 38 publications over 14 distinct years, with a maximum of 5 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	1	2
2006	1	1	2
2007	1	0	1
2009	0	2	2
2010	3	1	4
2011	0	4	4
2012	0	5	5
2013	3	0	3
2014	0	2	2
2015	2	2	4
2016	0	3	3
2019	0	3	3
2020	1	1	2
2021	0	1	1

Below are the most recent publications written about "CpG Islands" by people in Profiles.

Baker Frost D, da Silveira W, Hazard ES, Atanelishvili I, Wilson RC, Flume J, Day KL, Oates JC, Bogatkevich GS, Feghali-Bostwick C, Hardiman G, Ramos PS. Differential DNA Methylation Landscape in Skin Fibroblasts from African Americans with Systemic Sclerosis. Genes (Basel). 2021 01 20; 12(2).

View in: PubMed
Bertucci EM, Parrott BB. Is CpG Density the Link between Epigenetic Aging and Lifespan? Trends Genet. 2020 10; 36(10):725-727.

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Chen L, Wagner CL, Dong Y, Wang X, Shary JR, Huang Y, Hollis BW, Zhu H. Effects of Maternal Vitamin D3 Supplementation on Offspring Epigenetic Clock of Gestational Age at Birth: A Post-hoc Analysis of a Randomized Controlled Trial. Epigenetics. 2020 08; 15(8):830-840.

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Khezri A, Narud B, Stenseth EB, Johannisson A, Myromslien FD, Gaustad AH, Wilson RC, Lyle R, Morrell JM, Kommisrud E, Ahmad R. DNA methylation patterns vary in boar sperm cells with different levels of DNA fragmentation. BMC Genomics. 2019 Nov 27; 20(1):897.

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Ankam S, Rovini A, Baheti S, Hrstka R, Wu Y, Schmidt K, Wang H, Madigan N, Koenig LS, Stelzig K, Resch Z, Klein CJ, Sun Z, Staff NP. DNA methylation patterns in human iPSC-derived sensory neuronal differentiation. Epigenetics. 2019 09; 14(9):927-937.

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Ramos PS, Zimmerman KD, Haddad S, Langefeld CD, Medsger TA, Feghali-Bostwick CA. Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsets. Clin Epigenetics. 2019 04 04; 11(1):58.

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Henning AN, Haag JD, Smits BM, Gould MN. The Non-coding Mammary Carcinoma Susceptibility Locus, Mcs5c, Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation. PLoS Genet. 2016 08; 12(8):e1006261.

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Lavender CA, Cannady KR, Hoffman JA, Trotter KW, Gilchrist DA, Bennett BD, Burkholder AB, Burd CJ, Fargo DC, Archer TK. Downstream Antisense Transcription Predicts Genomic Features That Define the Specific Chromatin Environment at Mammalian Promoters. PLoS Genet. 2016 08; 12(8):e1006224.

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Guillette LJ, Parrott BB, Nilsson E, Haque MM, Skinner MK. Epigenetic programming alterations in alligators from environmentally contaminated lakes. Gen Comp Endocrinol. 2016 11 01; 238:4-12.

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Levine AJ, Phipps AI, Baron JA, Buchanan DD, Ahnen DJ, Cohen SA, Lindor NM, Newcomb PA, Rosty C, Haile RW, Laird PW, Weisenberger DJ. Clinicopathologic Risk Factor Distributions for MLH1 Promoter Region Methylation in CIMP-Positive Tumors. Cancer Epidemiol Biomarkers Prev. 2016 Jan; 25(1):68-75.

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