Immunoglobulin A

"Immunoglobulin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions.

Descriptor ID	D007070
MeSH Number(s)	D12.776.124.486.485.114.619.026 D12.776.124.790.651.114.619.026 D12.776.377.715.548.114.619.026
Concept/Terms	Immunoglobulin A Immunoglobulin A IgA IgA1 IgA1 IgA2 IgA2

Below are MeSH descriptors whose meaning is more general than "Immunoglobulin A".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Immunoproteins [D12.776.124.486]
Immunoglobulins [D12.776.124.486.485]
Antibodies [D12.776.124.486.485.114]
Immunoglobulin Isotypes [D12.776.124.486.485.114.619]
Immunoglobulin A [D12.776.124.486.485.114.619.026]
Serum Globulins [D12.776.124.790]
Immunoglobulins [D12.776.124.790.651]
Antibodies [D12.776.124.790.651.114]
Immunoglobulin Isotypes [D12.776.124.790.651.114.619]
Immunoglobulin A [D12.776.124.790.651.114.619.026]
Globulins [D12.776.377]
Serum Globulins [D12.776.377.715]
Immunoglobulins [D12.776.377.715.548]
Antibodies [D12.776.377.715.548.114]
Immunoglobulin Isotypes [D12.776.377.715.548.114.619]
Immunoglobulin A [D12.776.377.715.548.114.619.026]

Below are MeSH descriptors whose meaning is related to "Immunoglobulin A".

Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin A".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immunoglobulin A" by people in this website by year, and whether "Immunoglobulin A" was a major or minor topic of these publications.

Bar chart showing 39 publications over 21 distinct years, with a maximum of 4 publications in 1999 and 2001 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	2	0	2
1995	0	1	1
1997	1	1	2
1998	0	1	1
1999	1	3	4
2001	2	2	4
2003	0	2	2
2004	1	0	1
2005	1	0	1
2006	0	2	2
2007	2	1	3
2008	0	1	1
2009	1	0	1
2011	0	1	1
2015	1	1	2
2016	0	1	1
2017	0	2	2
2019	0	1	1
2020	1	0	1
2021	0	4	4
2022	1	1	2

Below are the most recent publications written about "Immunoglobulin A" by people in Profiles.

Gudi R, Roy S, Sun W, Vasu C. Preclinical stage abundance and nuclear antigen reactivity of faecal Immunoglobulin A vary among males and females of lupus-prone mouse models. Immunology. 2022 04; 165(4):497-507.

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Wei J, Hegde VL, Yanamandra AV, O'Hara MP, Keegan B, Jones KM, Strych U, Bottazzi ME, Zhan B, Sastry KJ, Hotez PJ. Mucosal Vaccination With Recombinant Tm-WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice. Front Immunol. 2022; 13:800295.

View in: PubMed
Stephens WZ, Kubinak JL, Ghazaryan A, Bauer KM, Bell R, Buhrke K, Chiaro TR, Weis AM, Tang WW, Monts JK, Soto R, Ekiz HA, O'Connell RM, Round JL. Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition. Cell Rep. 2021 11 02; 37(5):109916.

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Valcarce V, Stafford LS, Neu J, Cacho N, Parker L, Mueller M, Burchfield DJ, Li N, Larkin J. Detection of SARS-CoV-2-Specific IgA in the Human Milk of COVID-19 Vaccinated Lactating Health Care Workers. Breastfeed Med. 2021 12; 16(12):1004-1009.

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Ost KS, O'Meara TR, Stephens WZ, Chiaro T, Zhou H, Penman J, Bell R, Catanzaro JR, Song D, Singh S, Call DH, Hwang-Wong E, Hanson KE, Valentine JF, Christensen KA, O'Connell RM, Cormack B, Ibrahim AS, Palm NW, Noble SM, Round JL. Adaptive immunity induces mutualism between commensal eukaryotes. Nature. 2021 08; 596(7870):114-118.

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Elkhalifa M, Orbai AM, Magder LS, Petri M, Alarcón GS, Gordon C, Merrill J, Fortin PR, Bruce IN, Isenberg D, Wallace D, Nived O, Ramsey-Goldman R, Bae SC, Hanly JG, Sanchez-Guerrero J, Clarke AE, Aranow C, Manzi S, Urowitz M, Gladman DD, Kalunian K, Werth VP, Zoma A, Bernatsky S, Khamashta M, Jacobsen S, Buyon JP, Dooley MA, Vollenhoven RV, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim S, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG. Anti-beta 2 glycoprotein I IgA in the SLICC classification criteria dataset. Lupus. 2021 Jul; 30(8):1283-1288.

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Sun W, Gudi RR, Johnson BM, Vasu C. Abundance and nuclear antigen reactivity of intestinal and fecal Immunoglobulin A in lupus-prone mice at younger ages correlate with the onset of eventual systemic autoimmunity. Sci Rep. 2020 08 31; 10(1):14258.

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Mohammed AD, Khan MAW, Chatzistamou I, Chamseddine D, Williams-Kang K, Perry M, Enos R, Murphy A, Gomez G, Aladhami A, Oskeritzian CA, Jolly A, Chang Y, He S, Pan Z, Kubinak JL. Gut Antibody Deficiency in a Mouse Model of CVID Results in Spontaneous Development of a Gluten-Sensitive Enteropathy. Front Immunol. 2019; 10:2484.

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Binder SR, Litwin CM. Anti-phospholipid Antibodies and Smoking: An Overview. Clin Rev Allergy Immunol. 2017 Aug; 53(1):1-13.

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Hua Y, Yang Y, Sun S, Iwanowycz S, Westwater C, Reizis B, Li Z, Liu B. Gut homeostasis and regulatory T cell induction depend on molecular chaperone gp96 in CD11c+ cells. Sci Rep. 2017 05 19; 7(1):2171.

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