"Immune Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (fetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc.
| Descriptor ID |
D007108
|
| MeSH Number(s) |
G12.535.425
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Immune Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Immune Tolerance".
This graph shows the total number of publications written about "Immune Tolerance" by people in this website by year, and whether "Immune Tolerance" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 3 | 1 | 4 |
| 2003 | 1 | 2 | 3 |
| 2004 | 3 | 0 | 3 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 3 | 2 | 5 |
| 2008 | 0 | 2 | 2 |
| 2009 | 4 | 2 | 6 |
| 2010 | 2 | 1 | 3 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 2 | 4 |
| 2014 | 1 | 3 | 4 |
| 2015 | 2 | 4 | 6 |
| 2016 | 1 | 1 | 2 |
| 2018 | 3 | 3 | 6 |
| 2019 | 3 | 2 | 5 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Immune Tolerance" by people in Profiles.
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Activation of T cell checkpoint pathways during ?-cell antigen presentation by engineered dendritic cells promotes protection from type 1 diabetes. Immunology. 2022 07; 166(3):341-356.
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Nanotherapeutics in transplantation: How do we get to clinical implementation? Am J Transplant. 2022 05; 22(5):1293-1298.
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Prostaglandin I2 signaling licenses Treg suppressive function and prevents pathogenic reprogramming. J Clin Invest. 2021 04 01; 131(7).
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From Suppressor T cells to Regulatory T cells: How the Journey That Began with the Discovery of the Toxic Effects of TCDD Led to Better Understanding of the Role of AhR in Immunoregulation. Int J Mol Sci. 2020 Oct 22; 21(21).
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Cytotrophoblasts suppress macrophage-mediated inflammation through a contact-dependent mechanism. Am J Reprod Immunol. 2021 03; 85(3):e13352.
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Effects of vitamin D supplementation on circulating concentrations of growth factors and immune-mediators in healthy women during pregnancy. Pediatr Res. 2021 02; 89(3):554-562.
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AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes. J Immunol. 2019 10 01; 203(7):1830-1844.
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Engineered Dendritic Cell-Directed Concurrent Activation of Multiple T cell Inhibitory Pathways Induces Robust Immune Tolerance. Sci Rep. 2019 08 19; 9(1):12065.
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MicroRNA-92 Expression in CD133+ Melanoma Stem Cells Regulates Immunosuppression in the Tumor Microenvironment via Integrin-Dependent Activation of TGF?. Cancer Res. 2019 07 15; 79(14):3622-3635.
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Complex dietary polysaccharide modulates gut immune function and microbiota, and promotes protection from autoimmune diabetes. Immunology. 2019 05; 157(1):70-85.