"Receptor, Muscarinic M1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific subtype of muscarinic receptor that has a high affinity for the drug PIRENZEPINE. It is found in the peripheral GANGLIA where it signals a variety of physiological functions such as GASTRIC ACID secretion and BRONCHOCONSTRICTION. This subtype of muscarinic receptor is also found in neuronal tissues including the CEREBRAL CORTEX and HIPPOCAMPUS where it mediates the process of MEMORY and LEARNING.
| Descriptor ID |
D043643
|
| MeSH Number(s) |
D12.776.543.750.695.475.100 D12.776.543.750.720.360.500.099
|
| Concept/Terms |
Receptor, Muscarinic M1- Receptor, Muscarinic M1
- M1 Receptor, Muscarinic
- Muscarinic M1 Receptor
- Receptors, Muscarinic M1
- M1 Receptors, Muscarinic
- Muscarinic M1 Receptors
- Muscarinic Receptor M1
- M1, Muscarinic Receptor
- Receptor M1, Muscarinic
- Muscarinic Receptors M1
- M1, Muscarinic Receptors
- Receptors M1, Muscarinic
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Muscarinic M1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Muscarinic [D12.776.543.750.695.475]
- Receptor, Muscarinic M1 [D12.776.543.750.695.475.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Muscarinic [D12.776.543.750.720.360.500]
- Receptor, Muscarinic M1 [D12.776.543.750.720.360.500.099]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Muscarinic M1".
This graph shows the total number of publications written about "Receptor, Muscarinic M1" by people in this website by year, and whether "Receptor, Muscarinic M1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor, Muscarinic M1" by people in Profiles.
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Colocalization of M1 muscarinic cholinergic receptors and NMDA receptors in dendrites and spines of pyramidal neurons of the mouse basolateral amygdala: An ultrastructural analysis. Neurosci Lett. 2022 05 14; 779:136624.
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Neuronal localization of m1 muscarinic receptor immunoreactivity in the monkey basolateral amygdala. J Comp Neurol. 2021 07 01; 529(10):2450-2463.
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Diverse glutamatergic inputs target spines expressing M1 muscarinic receptors in the basolateral amygdala: An ultrastructural analysis. Brain Res. 2019 11 01; 1722:146349.
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Muscarinic M1 Receptor Modulation of Synaptic Plasticity in Nucleus Accumbens of Wild-Type and Fragile X Mice. ACS Chem Neurosci. 2018 09 19; 9(9):2233-2240.
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Synthesis and biological evaluation of ranitidine analogs as multiple-target-directed cognitive enhancers for the treatment of Alzheimer's disease. Bioorg Med Chem Lett. 2016 11 15; 26(22):5573-5579.
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Muscarinic cholinergic receptor M1 in the rat basolateral amygdala: ultrastructural localization and synaptic relationships to cholinergic axons. J Comp Neurol. 2013 Jun 01; 521(8):1743-59.
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Neuronal localization of m1 muscarinic receptor immunoreactivity in the rat basolateral amygdala. Brain Struct Funct. 2010 Jul; 215(1):37-48.
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Sympathetic sprouting in visual cortex stimulated by cholinergic denervation rescues expression of two forms of long-term depression at layer 2/3 synapses. Neuroscience. 2010 Jul 14; 168(3):591-604.
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Intensity and duration of chronic ethanol exposure is critical for subsequent escalation of voluntary ethanol drinking in mice. Alcohol Clin Exp Res. 2009 Nov; 33(11):1893-900.
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Coactivation of M(1) muscarinic and alpha1 adrenergic receptors stimulates extracellular signal-regulated protein kinase and induces long-term depression at CA3-CA1 synapses in rat hippocampus. J Neurosci. 2008 May 14; 28(20):5350-8.