Dose-Response Relationship, Drug
"Dose-Response Relationship, Drug" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relationship between the dose of an administered drug and the response of the organism to the drug.
| Descriptor ID |
D004305
|
| MeSH Number(s) |
G07.690.773.875 G07.690.936.500
|
| Concept/Terms |
Dose-Response Relationship, Drug- Dose-Response Relationship, Drug
- Dose-Response Relationships, Drug
- Drug Dose-Response Relationship
- Drug Dose-Response Relationships
- Relationship, Drug Dose-Response
- Relationships, Drug Dose-Response
- Dose Response Relationship, Drug
|
Below are MeSH descriptors whose meaning is more general than "Dose-Response Relationship, Drug".
Below are MeSH descriptors whose meaning is more specific than "Dose-Response Relationship, Drug".
This graph shows the total number of publications written about "Dose-Response Relationship, Drug" by people in this website by year, and whether "Dose-Response Relationship, Drug" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 23 | 24 |
| 1995 | 0 | 31 | 31 |
| 1996 | 0 | 26 | 26 |
| 1997 | 0 | 18 | 18 |
| 1998 | 0 | 21 | 21 |
| 1999 | 0 | 28 | 28 |
| 2000 | 0 | 23 | 23 |
| 2001 | 0 | 35 | 35 |
| 2002 | 0 | 31 | 31 |
| 2003 | 0 | 66 | 66 |
| 2004 | 0 | 57 | 57 |
| 2005 | 0 | 69 | 69 |
| 2006 | 0 | 68 | 68 |
| 2007 | 0 | 56 | 56 |
| 2008 | 0 | 64 | 64 |
| 2009 | 0 | 43 | 43 |
| 2010 | 0 | 43 | 43 |
| 2011 | 0 | 51 | 51 |
| 2012 | 0 | 39 | 39 |
| 2013 | 0 | 44 | 44 |
| 2014 | 1 | 52 | 53 |
| 2015 | 0 | 39 | 39 |
| 2016 | 0 | 58 | 58 |
| 2017 | 0 | 38 | 38 |
| 2018 | 0 | 37 | 37 |
| 2019 | 0 | 23 | 23 |
| 2020 | 2 | 19 | 21 |
| 2021 | 1 | 13 | 14 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Dose-Response Relationship, Drug" by people in Profiles.
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An adaptive clinical trial design to identify the target dose of tenecteplase for treatment of acute pulmonary embolism. Clin Trials. 2022 Dec; 19(6):636-646.
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Inhibition of neprilysin with sacubitril without RAS blockage aggravates renal disease in Dahl SS rats. Ren Fail. 2021 Dec; 43(1):315-324.
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A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts. Drug Deliv. 2021 Dec; 28(1):1432-1442.
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Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE. Eur J Med Chem. 2022 Jan 05; 227:113926.
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Phase 1 Trial of ALRN-6924, a Dual Inhibitor of MDMX and MDM2, in Patients with Solid Tumors and Lymphomas Bearing Wild-type TP53. Clin Cancer Res. 2021 10 01; 27(19):5236-5247.
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Targeted delivery of pentagalloyl glucose inhibits matrix metalloproteinase activity and preserves elastin in emphysematous lungs. Respir Res. 2021 Sep 18; 22(1):249.
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Identification of a potent Nrf2 displacement activator among aspirin-containing prodrugs. Neurochem Int. 2021 10; 149:105148.
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Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases. Breast Cancer Res. 2021 07 27; 23(1):76.
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Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells. J Med Chem. 2021 07 22; 64(14):9916-9925.
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Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa. Elife. 2021 06 29; 10.