"Melatonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
Descriptor ID |
D008550
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MeSH Number(s) |
D03.633.100.473.914.481 D06.472.506
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Melatonin".
Below are MeSH descriptors whose meaning is more specific than "Melatonin".
This graph shows the total number of publications written about "Melatonin" by people in this website by year, and whether "Melatonin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2001 | 1 | 0 | 1 |
2004 | 1 | 1 | 2 |
2006 | 3 | 0 | 3 |
2007 | 4 | 0 | 4 |
2008 | 1 | 0 | 1 |
2009 | 2 | 1 | 3 |
2010 | 3 | 0 | 3 |
2013 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2020 | 2 | 0 | 2 |
2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Melatonin" by people in Profiles.
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Zhang J, Jiang H, Du K, Xie T, Wang B, Chen C, Reiter RJ, Cen B, Yuan Y. Pan-cancer analyses reveal genomics and clinical characteristics of the melatonergic regulators in cancer. J Pineal Res. 2021 Oct; 71(3):e12758.
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Cahill T, da Silveira WA, Renaud L, Williamson T, Wang H, Chung D, Overton I, Chan SSL, Hardiman G. Induced Torpor as a Countermeasure for Low Dose Radiation Exposure in a Zebrafish Model. Cells. 2021 04 14; 10(4).
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Puente-Moncada N, Turos-Cabal M, Sánchez-Sánchez AM, Antolín I, Herrera F, Rodriguez-Blanco J, Duarte-Olivenza C, Rodriguez C, Martín V. Role of glucose metabolism in the differential antileukemic effect of melatonin on wild-type and FLT3-ITD mutant cells. Oncol Rep. 2020 07; 44(1):293-302.
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Zhang J, Xie T, Zhong X, Jiang HL, Li R, Wang BY, Huang XT, Cen BH, Yuan YW. Melatonin reverses nasopharyngeal carcinoma cisplatin chemoresistance by inhibiting the Wnt/ß-catenin signaling pathway. Aging (Albany NY). 2020 03 23; 12(6):5423-5438.
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Reynolds AC, Marshall NS, Hill CL, Adams RJ. Systematic review of the efficacy of commonly prescribed pharmacological treatments for primary treatment of sleep disturbance in patients with diagnosed autoimmune disease. Sleep Med Rev. 2020 02; 49:101232.
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Pappolla MA, Matsubara E, Vidal R, Pacheco-Quinto J, Poeggeler B, Zagorski M, Sambamurti K. Melatonin Treatment Enhances Aß Lymphatic Clearance in a Transgenic Mouse Model of Amyloidosis. Curr Alzheimer Res. 2018; 15(7):637-642.
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Matheson E, Hainer BL. Insomnia: Pharmacologic Therapy. Am Fam Physician. 2017 Jul 01; 96(1):29-35.
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Baburina Y, Odinokova I, Azarashvili T, Akatov V, Lemasters JJ, Krestinina O. 2',3'-Cyclic nucleotide 3'-phosphodiesterase as a messenger of protection of the mitochondrial function during melatonin treatment in aging. Biochim Biophys Acta Biomembr. 2017 Jan; 1859(1):94-103.
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Rodriguez C, Martín V, Herrera F, García-Santos G, Rodriguez-Blanco J, Casado-Zapico S, Sánchez-Sánchez AM, Suárez S, Puente-Moncada N, Anítua MJ, Antolín I. Mechanisms involved in the pro-apoptotic effect of melatonin in cancer cells. Int J Mol Sci. 2013 Mar 25; 14(4):6597-613.
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Zhang R, Hrushesky WJ, Wood PA, Lee SH, Hunt RC, Jahng WJ. Melatonin reprogrammes proteomic profile in light-exposed retina in vivo. Int J Biol Macromol. 2010 Aug 01; 47(2):255-60.