Interleukin 1 Receptor Antagonist Protein

"Interleukin 1 Receptor Antagonist Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.

Descriptor ID	D053590
MeSH Number(s)	D12.644.276.374.460 D12.776.467.374.460 D23.529.374.460
Concept/Terms	Interleukin 1 Receptor Antagonist Protein Interleukin 1 Receptor Antagonist Protein IL1 Febrile Inhibitor Febrile Inhibitor, IL1 IL-1Ra Urine-Derived IL1 Inhibitor IL1 Inhibitor, Urine-Derived Urine Derived IL1 Inhibitor IL-1 Inhibitor, Urine IL 1 Inhibitor, Urine Urine IL-1 Inhibitor Interleukin 1 Inhibitor, Urine Antril Antril Kineret Kineret Anakinra Anakinra

Below are MeSH descriptors whose meaning is more general than "Interleukin 1 Receptor Antagonist Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukin 1 Receptor Antagonist Protein [D12.644.276.374.460]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukin 1 Receptor Antagonist Protein [D12.776.467.374.460]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukin 1 Receptor Antagonist Protein [D23.529.374.460]

Below are MeSH descriptors whose meaning is related to "Interleukin 1 Receptor Antagonist Protein".

Below are MeSH descriptors whose meaning is more specific than "Interleukin 1 Receptor Antagonist Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin 1 Receptor Antagonist Protein" by people in this website by year, and whether "Interleukin 1 Receptor Antagonist Protein" was a major or minor topic of these publications.

Bar chart showing 10 publications over 10 distinct years, with a maximum of 1 publications in 2004 and 2006 and 2009 and 2011 and 2013 and 2014 and 2015 and 2017 and 2021 and 2022

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	0	1	1
2006	0	1	1
2009	0	1	1
2011	1	0	1
2013	0	1	1
2014	1	0	1
2015	1	0	1
2017	1	0	1
2021	1	0	1
2022	1	0	1

Below are the most recent publications written about "Interleukin 1 Receptor Antagonist Protein" by people in Profiles.

Diorio C, Vatsayan A, Talleur AC, Annesley C, Jaroscak JJ, Shalabi H, Ombrello AK, Hudspeth M, Maude SL, Gardner RA, Shah NN. Anakinra utilization in refractory pediatric CAR T-cell associated toxicities. Blood Adv. 2022 06 14; 6(11):3398-3403.

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Kelly SB, Stojanovska V, Zahra VA, Moxham A, Miller SL, Moss TJM, Hooper SB, Nold MF, Nold-Petry CA, Dean JM, Bennet L, Polglase GR, Gunn AJ, Galinsky R. Interleukin-1 blockade attenuates white matter inflammation and oligodendrocyte loss after progressive systemic lipopolysaccharide exposure in near-term fetal sheep. J Neuroinflammation. 2021 Aug 31; 18(1):189.

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Hutson LW, Lebonville CL, Jones ME, Fuchs RA, Lysle DT. Interleukin-1 signaling in the basolateral amygdala is necessary for heroin-conditioned immunosuppression. Brain Behav Immun. 2017 May; 62:171-179.

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Gutowski SM, Shoemaker JT, Templeman KL, Wei Y, Latour RA, Bellamkonda RV, LaPlaca MC, García AJ. Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes. Biomaterials. 2015 Mar; 44:55-70.

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Peddareddygari LR, Sen S, Pahwa A, Levenstien MA, Grewal RP. Analysis of the interleukin-1 receptor antagonist gene variable number tandem repeats in ischemic stroke. J Stroke Cerebrovasc Dis. 2014 Jul; 23(6):1599-603.

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Du M, Basu A, Fu D, Wu M, Centola M, Jenkins AJ, Hanssen KF, Garg SK, Hammad SM, Scardo JA, Aston CE, Lyons TJ. Serum inflammatory markers and preeclampsia in type 1 diabetes: a prospective study. Diabetes Care. 2013 Jul; 36(7):2054-61.

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Freeman LR, Small BJ, Bickford PC, Umphlet C, Granholm AC. A high-fat/high-cholesterol diet inhibits growth of fetal hippocampal transplants via increased inflammation. Cell Transplant. 2011; 20(10):1499-514.

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Iwasaki LR, Chandler JR, Marx DB, Pandey JP, Nickel JC. IL-1 gene polymorphisms, secretion in gingival crevicular fluid, and speed of human orthodontic tooth movement. Orthod Craniofac Res. 2009 May; 12(2):129-40.

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Iwasaki LR, Gibson CS, Crouch LD, Marx DB, Pandey JP, Nickel JC. Speed of tooth movement is related to stress and IL-1 gene polymorphisms. Am J Orthod Dentofacial Orthop. 2006 Dec; 130(6):698.e1-9.

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Parks CG, Cooper GS, Dooley MA, Treadwell EL, St Clair EW, Gilkeson GS, Pandey JP. Systemic lupus erythematosus and genetic variation in the interleukin 1 gene cluster: a population based study in the southeastern United States. Ann Rheum Dis. 2004 Jan; 63(1):91-4.

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