"Hepatocyte Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. Its receptor is PROTO-ONCOGENE PROTEINS C-MET.
| Descriptor ID |
D017228
|
| MeSH Number(s) |
D12.644.276.374.420 D12.776.467.374.420 D23.529.374.420
|
| Concept/Terms |
Hepatocyte Growth Factor- Hepatocyte Growth Factor
- Factor, Hepatocyte Growth
- Growth Factor, Hepatocyte
- Scatter Factor
- Factor, Scatter
- Hepatopoietin
- Hepatopoietin A
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Growth Factor".
This graph shows the total number of publications written about "Hepatocyte Growth Factor" by people in this website by year, and whether "Hepatocyte Growth Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 3 | 0 | 3 |
| 2001 | 1 | 0 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 4 | 2 | 6 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Hepatocyte Growth Factor" by people in Profiles.
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Inflammation-Induced Metastatic Colonization of the Lung Is Facilitated by Hepatocyte Growth Factor-Secreting Monocyte-Derived Macrophages. Mol Cancer Res. 2021 12; 19(12):2096-2109.
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Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repair. J Biol Chem. 2021 09; 297(3):101079.
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D1398G Variant of MET Is Associated with Impaired Signaling of Hepatocyte Growth Factor in Alveolar Epithelial Cells and Lung Fibroblasts. PLoS One. 2016; 11(9):e0162357.
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A new outlet for pulmonary arterial hypertension. J Thorac Cardiovasc Surg. 2015 Sep; 150(3):643-4.
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The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014 Jul; 34(13):2517-32.
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Novel MAPK-dependent and -independent tubulogenes identified via microarray analysis of 3D-cultured Madin-Darby canine kidney cells. Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1047-58.
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Intercellular transfer of GPRC5B via exosomes drives HGF-mediated outward growth. Curr Biol. 2014 Jan 20; 24(2):199-204.
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Overexpression of c-Met and CD44v6 receptors contributes to autocrine TGF-?1 signaling in interstitial lung disease. J Biol Chem. 2014 Mar 14; 289(11):7856-72.
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A common p53 mutation (R175H) activates c-Met receptor tyrosine kinase to enhance tumor cell invasion. Cancer Biol Ther. 2013 Sep; 14(9):853-9.
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Racial differences between blacks and whites with systemic sclerosis. Curr Opin Rheumatol. 2012 Nov; 24(6):642-8.