"Neurofibroma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A moderately firm, benign, encapsulated tumor resulting from proliferation of SCHWANN CELLS and FIBROBLASTS that includes portions of nerve fibers. The tumors usually develop along peripheral or cranial nerves and are a central feature of NEUROFIBROMATOSIS 1, where they may occur intracranially or involve spinal roots. Pathologic features include fusiform enlargement of the involved nerve. Microscopic examination reveals a disorganized and loose cellular pattern with elongated nuclei intermixed with fibrous strands. (From Adams et al., Principles of Neurology, 6th ed, p1016)
| Descriptor ID |
D009455
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| MeSH Number(s) |
C04.557.580.600.580 C10.551.775.500.750 C10.668.829.725.500.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Neurofibroma".
Below are MeSH descriptors whose meaning is more specific than "Neurofibroma".
This graph shows the total number of publications written about "Neurofibroma" by people in this website by year, and whether "Neurofibroma" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Neurofibroma" by people in Profiles.
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Balmer JC, Mikhaylov Y, Lewin DN, Mahvi DM, Ramsay Camp E. Synchronous Upper Intestinal Neurofibromas and Duodenal Periampullary Well-Differentiated Neuroendocrine Tumor Associated With Neurofibromatosis 1. Am Surg. 2021 Jan; 87(1):128-130.
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Ortonne N, Wolkenstein P, Blakeley JO, Korf B, Plotkin SR, Riccardi VM, Miller DC, Huson S, Peltonen J, Rosenberg A, Carroll SL, Verma SK, Mautner V, Upadhyaya M, Stemmer-Rachamimov A. Cutaneous neurofibromas: Current clinical and pathologic issues. Neurology. 2018 07 10; 91(2 Suppl 1):S5-S13.
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Sharma A, Sharma A, Sharma R, Dewan Y. Management of iatrogenic vertebral artery injury following cervical neurofibroma excision: a case report. Br J Neurosurg. 2017 Aug; 31(4):478-480.
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Carroll SL. The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics. Am J Pathol. 2016 Mar; 186(3):464-77.
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Brosius SN, Turk AN, Byer SJ, Brossier NM, Kohli L, Whitmire A, Mikhail FM, Roth KA, Carroll SL. Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis. Acta Neuropathol. 2014 Apr; 127(4):573-91.
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Kazmi SJ, Byer SJ, Eckert JM, Turk AN, Huijbregts RP, Brossier NM, Grizzle WE, Mikhail FM, Roth KA, Carroll SL. Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis. Am J Pathol. 2013 Mar; 182(3):646-67.
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Riley J, Spiotta A, Boulis N. Experimental therapeutic approaches to peripheral nerve tumors. Neurosurg Focus. 2007 Jun 15; 22(6):E2.
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DeVault KR, Miller LS, Yaghsezian H, Spirig AM, Dhuria M, Armenti FR, Connell DC, Martin P, Castell DO. Acute esophageal hemorrhage from a vagal neurilemoma. Gastroenterology. 1992 Mar; 102(3):1059-61.
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Neville BW, Hann J, Narang R, Garen P. Oral neurofibrosarcoma associated with neurofibromatosis type I. Oral Surg Oral Med Oral Pathol. 1991 Oct; 72(4):456-61.
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Osguthorpe JD, Saunders RA, Adkins WY. Evaluation of and access to posterior orbital tumors. Laryngoscope. 1983 Jun; 93(6):766-71.