"Leucine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential branched-chain amino acid important for hemoglobin formation.
| Descriptor ID |
D007930
|
| MeSH Number(s) |
D12.125.070.637 D12.125.142.441
|
| Concept/Terms |
Leucine- Leucine
- L-Leucine
- Leucine, L-Isomer
- L-Isomer Leucine
- Leucine, L Isomer
|
Below are MeSH descriptors whose meaning is more general than "Leucine".
Below are MeSH descriptors whose meaning is more specific than "Leucine".
This graph shows the total number of publications written about "Leucine" by people in this website by year, and whether "Leucine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1995 | 0 | 1 | 1 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 2 | 2 |
| 2000 | 2 | 1 | 3 |
| 2001 | 1 | 1 | 2 |
| 2003 | 2 | 0 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 3 | 5 |
| 2008 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Leucine" by people in Profiles.
-
A Nonhemolytic Group B Streptococcus Strain Exhibits Hypervirulence. J Infect Dis. 2018 03 05; 217(6):983-987.
-
Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats. Physiol Rep. 2016 09; 4(17).
-
Physicochemical Properties of Microencapsulated ?-3 Salmon Oil with Egg White Powder. J Food Sci. 2016 Mar; 81(3):E600-9.
-
Brain pyroglutamate amyloid-? is produced by cathepsin B and is reduced by the cysteine protease inhibitor E64d, representing a potential Alzheimer's disease therapeutic. J Alzheimers Dis. 2014; 41(1):129-49.
-
Brief early-life non-specific incorporation of deuterium extends mean life span in Drosophila melanogaster without affecting fecundity. Rejuvenation Res. 2013 Apr; 16(2):98-104.
-
The cysteine protease inhibitor, E64d, reduces brain amyloid-? and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B, but not BACE1, ?-secretase activity. J Alzheimers Dis. 2011; 26(2):387-408.
-
Association between p.Leu54Met polymorphism at the paraoxonase-1 gene and plantar fascia thickness in young subjects with type 1 diabetes. Diabetes Care. 2008 Aug; 31(8):1585-9.
-
Inhibitors of cathepsin B improve memory and reduce beta-amyloid in transgenic Alzheimer disease mice expressing the wild-type, but not the Swedish mutant, beta-secretase site of the amyloid precursor protein. J Biol Chem. 2008 Mar 21; 283(12):7745-53.
-
Rad GTPase deficiency leads to cardiac hypertrophy. Circulation. 2007 Dec 18; 116(25):2976-2983.
-
Direct evidence for calpain involvement in apoptotic death of neurons in spinal cord injury in rats and neuroprotection with calpain inhibitor. Neurochem Res. 2007 Dec; 32(12):2210-6.