Restless Legs Syndrome

"Restless Legs Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep.

Descriptor ID	D012148
MeSH Number(s)	C10.803 C10.886.425.800.700 C10.886.659.634 F03.870.400.800.700 F03.870.664.634
Concept/Terms	Restless Legs Syndrome Restless Legs Syndrome Restless Legs Willis Ekbom Disease Disease, Willis Ekbom Wittmaack-Ekbom Syndrome Syndrome, Wittmaack-Ekbom Willis-Ekbom Disease Disease, Willis-Ekbom Willis-Ekbom Syndrome Syndrome, Willis-Ekbom Wittmaack Ekbom Syndrome Syndrome, Wittmaack Ekbom Restless Leg Syndrome Syndrome, Restless Leg Willis Ekbom Syndrome Syndrome, Willis Ekbom

Below are MeSH descriptors whose meaning is more general than "Restless Legs Syndrome".

Diseases [C]
Nervous System Diseases [C10]
Restless Legs Syndrome [C10.803]
Sleep Wake Disorders [C10.886]
Dyssomnias [C10.886.425]
Sleep Disorders, Intrinsic [C10.886.425.800]
Restless Legs Syndrome [C10.886.425.800.700]
Parasomnias [C10.886.659]
Restless Legs Syndrome [C10.886.659.634]
Psychiatry and Psychology [F]
Mental Disorders [F03]
Sleep Wake Disorders [F03.870]
Dyssomnias [F03.870.400]
Sleep Disorders, Intrinsic [F03.870.400.800]
Restless Legs Syndrome [F03.870.400.800.700]
Parasomnias [F03.870.664]
Restless Legs Syndrome [F03.870.664.634]

Below are MeSH descriptors whose meaning is related to "Restless Legs Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Restless Legs Syndrome".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Restless Legs Syndrome" by people in this website by year, and whether "Restless Legs Syndrome" was a major or minor topic of these publications.

Bar chart showing 16 publications over 13 distinct years, with a maximum of 2 publications in 2004 and 2010 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Total
2000	1	1
2004	2	2
2005	1	1
2006	1	1
2008	1	1
2010	2	2
2011	1	1
2013	1	1
2014	1	1
2015	1	1
2017	2	2
2018	1	1
2019	1	1

Below are the most recent publications written about "Restless Legs Syndrome" by people in Profiles.

De Vloo P, Reddy GD, Rowland N, Sammartino F, Llinas M, Paul D, Murray BJ, Lang AE, Fasano A, Munhoz RP, Kalia SK. Successful spinal cord stimulation for severe medication-refractory restless legs syndrome. Mov Disord. 2019 04; 34(4):585-586.

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Sharon D, Allen RP, Martinez-Martin P, Walters AS, Ferini Strambi L, Högl B, Trotti LM, Buchfuhrer M, Swieca J, Bogan RK, Zak R, Hensley JG, Schaefer LA, Marelli S, Zucconi M, Stefani A, Holzknecht E, Olvera V, Meaklim H, Laska I, Becker PM. Validation of the self-administered version of the international Restless Legs Syndrome study group severity rating scale - The sIRLS. Sleep Med. 2019 02; 54:94-100.

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Appleton SL, Gill TK, Lang CJ, Taylor AW, McEvoy RD, Stocks NP, González-Chica DA, Adams RJ. Prevalence and comorbidity of sleep conditions in Australian adults: 2016 Sleep Health Foundation national survey. Sleep Health. 2018 02; 4(1):13-19.

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Geyer J, Bogan R. Identification and treatment of augmentation in patients with restless legs syndrome: practical recommendations. Postgrad Med. 2017 Sep; 129(7):667-675.

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Bogan RK, Lee DO, Buchfuhrer MJ, Jaros MJ, Kim R, Shang G. Treatment response to sleep, pain, and mood disturbance and their correlation with sleep disturbance in adult patients with moderate-to-severe primary restless legs syndrome: Pooled analyses from 3 trials of gabapentin enacarbil. Ann Med. 2015 May; 47(3):269-77.

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Bogan RK. From bench to bedside: An overview of rotigotine for the treatment of restless legs syndrome. Clin Ther. 2014 Mar 01; 36(3):436-55.

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Bogan RK, Cheray JA. Restless legs syndrome: a review of diagnosis and management in primary care. Postgrad Med. 2013 May; 125(3):99-111.

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Winkelman JW, Bogan RK, Schmidt MH, Hudson JD, DeRossett SE, Hill-Zabala CE. Randomized polysomnography study of gabapentin enacarbil in subjects with restless legs syndrome. Mov Disord. 2011 Sep; 26(11):2065-72.

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Hening WA, Allen RP, Ondo WG, Walters AS, Winkelman JW, Becker P, Bogan R, Fry JM, Kudrow DB, Lesh KW, Fichtner A, Schollmayer E. Rotigotine improves restless legs syndrome: a 6-month randomized, double-blind, placebo-controlled trial in the United States. Mov Disord. 2010 Aug 15; 25(11):1675-83.

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Bogan RK, Bornemann MA, Kushida CA, Trân PV, Barrett RW. Long-term maintenance treatment of restless legs syndrome with gabapentin enacarbil: a randomized controlled study. Mayo Clin Proc. 2010 Jun; 85(6):512-21.

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