Interleukin-17

"Interleukin-17" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A proinflammatory cytokine produced primarily by T-LYMPHOCYTES or their precursors. Several subtypes of interleukin-17 have been identified, each of which is a product of a unique gene.

Descriptor ID	D020381
MeSH Number(s)	D12.644.276.374.465.517 D12.776.467.374.465.517 D23.529.374.465.517
Concept/Terms	Interleukin-17 Interleukin-17 Interleukin 17 CTLA-8 IL-17 Interleukin-17F Interleukin-17F Interleukin 17F IL-17F Cytokine ML-1 Cytokine ML 1 Interleukin-17C Interleukin-17C Interleukin 17C IL-17C Cytokine CX2 CX2, Cytokine Interleukin-17E Interleukin-17E Interleukin 17E Interleukin-25 Interleukin 25 IL-17E IL 17E Interleukin-17A Interleukin-17A Interleukin 17A Cytotoxic T lymphocyte-Associated Antigen 8 Cytotoxic T lymphocyte Associated Antigen 8 IL-17A CTLA8 Interleukin-17B Interleukin-17B Interleukin 17B IL-17B

Below are MeSH descriptors whose meaning is more general than "Interleukin-17".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Interleukins [D12.644.276.374.465]
Interleukin-17 [D12.644.276.374.465.517]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Interleukins [D12.776.467.374.465]
Interleukin-17 [D12.776.467.374.465.517]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Interleukins [D23.529.374.465]
Interleukin-17 [D23.529.374.465.517]

Below are MeSH descriptors whose meaning is related to "Interleukin-17".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-17".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-17" by people in this website by year, and whether "Interleukin-17" was a major or minor topic of these publications.

Bar chart showing 37 publications over 13 distinct years, with a maximum of 4 publications in 2008 and 2011 and 2012 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	3	0	3
2008	3	1	4
2009	1	1	2
2010	1	1	2
2011	2	2	4
2012	0	4	4
2013	0	1	1
2014	0	4	4
2015	0	3	3
2016	2	1	3
2018	1	2	3
2019	0	3	3
2022	1	0	1

Below are the most recent publications written about "Interleukin-17" by people in Profiles.

Lennard Richard ML, Wirth JR, Khatiwada A, Chung D, Gilkeson GS, Cunningham MA. Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus. Immunology. 2022 Nov; 167(3):354-367.

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Al-Ghezi ZZ, Busbee PB, Alghetaa H, Nagarkatti PS, Nagarkatti M. Combination of cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), mitigates experimental autoimmune encephalomyelitis (EAE) by altering the gut microbiome. Brain Behav Immun. 2019 11; 82:25-35.

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Jackson L, Li W, Abdul Y, Dong G, Baban B, Ergul A. Diabetic Stroke Promotes a Sexually Dimorphic Expansion of T Cells. Neuromolecular Med. 2019 12; 21(4):445-453.

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Clayton S, Cauble E, Kumar A, Patil N, Ledford D, Kolliputi N, Lopes-Virella MF, Castell D, Richter J. Plasma levels of TNF-a, IL-6, IFN-?, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD). BMC Gastroenterol. 2019 Feb 11; 19(1):28.

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Eby JM, Smith AR, Riley TP, Cosgrove C, Ankney CM, Henning SW, Paulos CM, Garrett-Mayer E, Luiten RM, Nishimura MI, Baker BM, Le Poole IC. Molecular properties of gp100-reactive T-cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells. Pigment Cell Melanoma Res. 2019 01; 32(1):68-78.

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Singh I, Nath N, Saxena N, Singh AK, Won JS. Regulation of IL-10 and IL-17 mediated experimental autoimmune encephalomyelitis by S-nitrosoglutathione. Immunobiology. 2018 10; 223(10):549-554.

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Hu X, Majchrzak K, Liu X, Wyatt MM, Spooner CJ, Moisan J, Zou W, Carter LL, Paulos CM. In Vitro Priming of Adoptively Transferred T Cells with a ROR? Agonist Confers Durable Memory and Stemness In Vivo. Cancer Res. 2018 07 15; 78(14):3888-3898.

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Wu Y, Yu XZ. IL-17A ? Th17 in GvHD. Cell Mol Immunol. 2018 03; 15(3):282-283.

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Coughlin B, Schnabolk G, Joseph K, Raikwar H, Kunchithapautham K, Johnson K, Moore K, Wang Y, Rohrer B. Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and ?dT-cells. Sci Rep. 2016 Mar 31; 6:23794.

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Majchrzak K, Nelson MH, Bailey SR, Bowers JS, Yu XZ, Rubinstein MP, Himes RA, Paulos CM. Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic. Cancer Immunol Immunother. 2016 Mar; 65(3):247-59.

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