"Ketanserin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.
| Descriptor ID |
D007650
|
| MeSH Number(s) |
D03.383.621.365 D03.633.100.786.830.333
|
| Concept/Terms |
Ketanserin- Ketanserin
- 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione
R-41,468- R-41,468
- R 41,468
- R41,468
- R-41468
- R 41468
- R41468
|
Below are MeSH descriptors whose meaning is more general than "Ketanserin".
Below are MeSH descriptors whose meaning is more specific than "Ketanserin".
This graph shows the total number of publications written about "Ketanserin" by people in this website by year, and whether "Ketanserin" was a major or minor topic of these publications.
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Below are the most recent publications written about "Ketanserin" by people in Profiles.
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Ketanserin's sympatholytic and serotonin2-receptor blocking actions precede the hypotensive effects. J Hum Hypertens. 1994 Jan; 8(1):59-64.
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Effects of agonists, partial agonists, and antagonists on the regulation of 5-hydroxytryptamine2 receptors in P11 cells. Mol Pharmacol. 1993 May; 43(5):726-33.
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Desensitization and down-regulation of 5-HT2 receptors in P11 cells. J Pharmacol Exp Ther. 1991 Oct; 259(1):423-9.
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Effects of ketanserin on blood pressure and platelet aggregation in elderly men with mild hypertension. Am J Hypertens. 1988 Jul; 1(3 Pt 3):324S-330S.
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Characterization of binding sites for 3H-spiroperidol in human retina. Invest Ophthalmol Vis Sci. 1988 May; 29(5):687-94.
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Characterization of binding sites for [3H]spiroperidol. Biochem Pharmacol. 1987 Oct 01; 36(19):3255-64.
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Mechanism of the ocular hypotensive action of ketanserin. J Ocul Pharmacol. 1985; 1(2):137-47.