Connection

Dennis Watson to Proto-Oncogene Proteins

This is a "connection" page, showing publications Dennis Watson has written about Proto-Oncogene Proteins.
Connection Strength

2.841
  1. CaSm-mediated cellular transformation is associated with altered gene expression and messenger RNA stability. Cancer Res. 2005 Jul 15; 65(14):6228-36.
    View in: PubMed
    Score: 0.211
  2. The FLI-1 transcription factor is a short-lived phosphoprotein in T cells. J Biochem. 2005 Mar; 137(3):297-302.
    View in: PubMed
    Score: 0.205
  3. SP100 inhibits ETS1 activity in primary endothelial cells. Oncogene. 2005 Jan 27; 24(5):916-31.
    View in: PubMed
    Score: 0.204
  4. Ets-dependent regulation of target gene expression during megakaryopoiesis. J Biol Chem. 2004 Dec 10; 279(50):52183-90.
    View in: PubMed
    Score: 0.200
  5. The epithelial-specific Ets factors occupy a unique position in defining epithelial proliferation, differentiation and carcinogenesis. Anticancer Res. 2003 May-Jun; 23(3A):2125-31.
    View in: PubMed
    Score: 0.181
  6. Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor. Mol Cell Biol. 2000 Aug; 20(15):5643-52.
    View in: PubMed
    Score: 0.149
  7. ETS2 function is required to maintain the transformed state of human prostate cancer cells. Oncogene. 1998 Dec 03; 17(22):2883-8.
    View in: PubMed
    Score: 0.133
  8. FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements. Oncogene. 1997 Jan 16; 14(2):213-21.
    View in: PubMed
    Score: 0.117
  9. Generation and characterization of monoclonal antibodies against the ERGB/FLI-1 transcription factor. Hybridoma. 1995 Dec; 14(6):563-9.
    View in: PubMed
    Score: 0.108
  10. The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors. Cell Growth Differ. 1992 Oct; 3(10):705-13.
    View in: PubMed
    Score: 0.087
  11. Molecular analysis of the ets genes and their products. Crit Rev Oncog. 1990; 1(4):409-36.
    View in: PubMed
    Score: 0.072
  12. A unique amino-terminal sequence predicted for the chicken proto-ets protein. Virology. 1988 Nov; 167(1):1-7.
    View in: PubMed
    Score: 0.066
  13. Molecular organization of the chicken ets locus. Virology. 1988 May; 164(1):99-105.
    View in: PubMed
    Score: 0.064
  14. CaSm (LSm-1) overexpression in lung cancer and mesothelioma is required for transformed phenotypes. Am J Respir Cell Mol Biol. 2008 Jun; 38(6):671-8.
    View in: PubMed
    Score: 0.063
  15. Bystander effect contributes to the antitumor efficacy of CaSm antisense gene therapy in a preclinical model of advanced pancreatic cancer. Mol Ther. 2006 Feb; 13(2):357-65.
    View in: PubMed
    Score: 0.054
  16. Caspase-1 is a direct target gene of ETS1 and plays a role in ETS1-induced apoptosis. Cancer Res. 2005 Aug 15; 65(16):7205-13.
    View in: PubMed
    Score: 0.053
  17. Establishing a murine pancreatic cancer CaSm model: up-regulation of CaSm is required for the transformed phenotype of murine pancreatic adenocarcinoma. Mol Ther. 2005 Mar; 11(3):363-72.
    View in: PubMed
    Score: 0.051
  18. Interleukins 2 and 15 regulate Ets1 expression via ERK1/2 and MNK1 in human natural killer cells. J Biol Chem. 2005 Feb 11; 280(6):4772-8.
    View in: PubMed
    Score: 0.050
  19. Decreased expression of the Ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice. J Immunol. 2004 Nov 15; 173(10):6481-9.
    View in: PubMed
    Score: 0.050
  20. Dysregulation of granulocyte, erythrocyte, and NK cell lineages in Fli-1 gene-targeted mice. Blood. 2005 Jan 01; 105(1):95-102.
    View in: PubMed
    Score: 0.050
  21. Triplex DNA-mediated downregulation of Ets2 expression results in growth inhibition and apoptosis in human prostate cancer cells. Nucleic Acids Res. 2004; 32(14):4358-67.
    View in: PubMed
    Score: 0.049
  22. Ets proteins in biological control and cancer. J Cell Biochem. 2004 Apr 01; 91(5):896-903.
    View in: PubMed
    Score: 0.048
  23. Persistent down-regulation of Fli1, a suppressor of collagen transcription, in fibrotic scleroderma skin. Am J Pathol. 2003 Aug; 163(2):571-81.
    View in: PubMed
    Score: 0.046
  24. EAPII interacts with ETS1 and modulates its transcriptional function. Oncogene. 2003 May 08; 22(18):2699-709.
    View in: PubMed
    Score: 0.045
  25. Alterations in PMS2, MSH2 and MLH1 expression in human prostate cancer. Int J Oncol. 2003 May; 22(5):1033-43.
    View in: PubMed
    Score: 0.045
  26. CaSm antisense gene therapy: a novel approach for the treatment of pancreatic cancer. Anticancer Res. 2003 May-Jun; 23(3A):2007-13.
    View in: PubMed
    Score: 0.045
  27. Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta. J Biol Chem. 2002 Jun 07; 277(23):20399-408.
    View in: PubMed
    Score: 0.042
  28. Regulation of Ets function by protein - protein interactions. Oncogene. 2000 Dec 18; 19(55):6514-23.
    View in: PubMed
    Score: 0.038
  29. EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes. Oncogene. 2000 Feb 10; 19(6):745-53.
    View in: PubMed
    Score: 0.036
  30. Functional relationships among ETS gene family members. Leukemia. 1997 Apr; 11 Suppl 3:557-66.
    View in: PubMed
    Score: 0.030
  31. Multiple regulatory regions control the expression of Ets-1 in the developing mouse: vascular expression conferred by intron I. Cell Mol Biol (Noisy-le-grand). 1997 Mar; 43(2):211-25.
    View in: PubMed
    Score: 0.029
  32. Increased expression of the ETS-related transcription factor FLI-1/ERGB correlates with and can induce the megakaryocytic phenotype. Cell Growth Differ. 1996 Nov; 7(11):1525-34.
    View in: PubMed
    Score: 0.029
  33. Interaction of ETS-1 and ERGB/FLI-1 proteins with DNA is modulated by spacing between multiple binding sites as well as phosphorylation. Oncogene. 1996 Jan 04; 12(1):11-8.
    View in: PubMed
    Score: 0.027
  34. The EndoA enhancer contains multiple ETS binding site repeats and is regulated by ETS proteins. Oncogene. 1994 Feb; 9(2):469-77.
    View in: PubMed
    Score: 0.024
  35. Transactivation of GATA-1 promoter with ETS1, ETS2 and ERGB/Hu-FLI-1 proteins: stabilization of the ETS1 protein binding on GATA-1 promoter sequences by monoclonal antibody. Oncogene. 1993 Jul; 8(7):1783-90.
    View in: PubMed
    Score: 0.023
  36. Genomic dispersal of the ets gene family during metazoan evolution. Oncogene. 1992 Sep; 7(9):1713-9.
    View in: PubMed
    Score: 0.022
  37. D-elg, a member of the Drosophila ets gene family: sequence, expression and evolutionary comparison. Oncogene. 1991 Jul; 6(7):1175-83.
    View in: PubMed
    Score: 0.020
  38. The human ETS1 gene: genomic structure, promoter characterization and alternative splicing. Oncogene. 1991 Apr; 6(4):523-32.
    View in: PubMed
    Score: 0.020
  39. Molecular and functional characterization of the promoter of ETS2, the human c-ets-2 gene. Proc Natl Acad Sci U S A. 1990 Feb; 87(3):1047-51.
    View in: PubMed
    Score: 0.018
  40. Expression of human and viral ets genes in E. coli production of human ets-2-specific monoclonal antibodies. Oncogene Res. 1989; 5(1):61-6.
    View in: PubMed
    Score: 0.017
  41. Defects of DNA mismatch repair in human prostate cancer. Cancer Res. 2001 May 15; 61(10):4112-21.
    View in: PubMed
    Score: 0.010
  42. ETS family of genes in leukemia and Down syndrome. Am J Med Genet Suppl. 1990; 7:251-61.
    View in: PubMed
    Score: 0.004
  43. Viral myc genes and their cellular homologs. Gene Amplif Anal. 1986; 4:109-42.
    View in: PubMed
    Score: 0.003
  44. Oncogenes: molecular probes for clinical application in malignant diseases. Gene Amplif Anal. 1986; 4:253-77.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.