Igor Roninson to Cyclin-Dependent Kinase 8
This is a "connection" page, showing publications Igor Roninson has written about Cyclin-Dependent Kinase 8.
Connection Strength
4.728
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Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition. Cells. 2019 11 09; 8(11).
Score: 0.687
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Identifying Cancers Impacted by CDK8/19. Cells. 2019 08 03; 8(8).
Score: 0.674
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CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases. Cancer Res. 2018 12 01; 78(23):6594-6606.
Score: 0.633
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CDK8/19 Mediator kinases potentiate induction of transcription by NF?B. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10208-10213.
Score: 0.590
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Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer. Curr Cancer Drug Targets. 2015; 15(8):739-49.
Score: 0.490
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Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13799-804.
Score: 0.415
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Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in?vitro and in?vivo. Proc Natl Acad Sci U S A. 2022 08 09; 119(32):e2201073119.
Score: 0.207
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A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics. J Med Chem. 2022 02 24; 65(4):3420-3433.
Score: 0.200
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The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs. Cells. 2021 01 12; 10(1).
Score: 0.186
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Genome Editing As an Approach to the Study of in Vivo Transcription Reprogramming. Dokl Biochem Biophys. 2020 Jan; 490(1):43-46.
Score: 0.177
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Characterizing CDK8/19 Inhibitors through a NF?B-Dependent Cell-Based Assay. Cells. 2019 10 06; 8(10).
Score: 0.171
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Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer. Oncogene. 2018 08; 37(35):4792-4808.
Score: 0.155
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Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer. Oncotarget. 2017 Feb 21; 8(8):12558-12575.
Score: 0.142