Connection

Philip Howe to Animals

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This is a "connection" page, showing publications Philip Howe has written about Animals.
Philip Howe
Connection Strength
1.053
Animals
  1. Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity. Life Sci Alliance. 2021 09; 4(9).
    View in: PubMed
    Score: 0.056
  2. TGF? promotes breast cancer stem cell self-renewal through an ILEI/LIFR signaling axis. Oncogene. 2019 05; 38(20):3794-3811.
    View in: PubMed
    Score: 0.047
  3. Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1). J Biol Chem. 2018 07 20; 293(29):11401-11414.
    View in: PubMed
    Score: 0.045
  4. TGF-beta signaling in cancer: post-transcriptional regulation of EMT via hnRNP E1. Cytokine. 2019 06; 118:19-26.
    View in: PubMed
    Score: 0.044
  5. A CREB3-regulated ER-Golgi trafficking signature promotes metastatic progression in breast cancer. Oncogene. 2018 03; 37(10):1308-1325.
    View in: PubMed
    Score: 0.044
  6. A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression. Nat Cell Biol. 2017 Sep; 19(9):1105-1115.
    View in: PubMed
    Score: 0.043
  7. Cathepsin-B-mediated cleavage of Disabled-2 regulates TGF-?-induced autophagy. Nat Cell Biol. 2016 08; 18(8):851-63.
    View in: PubMed
    Score: 0.039
  8. PCBP1/HNRNP E1 Protects Chromosomal Integrity by Translational Regulation of CDC27. Mol Cancer Res. 2016 07; 14(7):634-46.
    View in: PubMed
    Score: 0.039
  9. Translational regulation of inhibin ?A by TGF? via the RNA-binding protein hnRNP E1 enhances the invasiveness of epithelial-to-mesenchymal transitioned cells. Oncogene. 2016 Mar 31; 35(13):1725-35.
    View in: PubMed
    Score: 0.037
  10. Establishment of a TGF?-induced post-transcriptional EMT gene signature. PLoS One. 2012; 7(12):e52624.
    View in: PubMed
    Score: 0.031
  11. Disabled-2 (Dab2) inhibits Wnt/?-catenin signalling by binding LRP6 and promoting its internalization through clathrin. EMBO J. 2012 May 16; 31(10):2336-49.
    View in: PubMed
    Score: 0.029
  12. Identification of an mRNP complex regulating tumorigenesis at the translational elongation step. Mol Cell. 2011 Feb 18; 41(4):419-31.
    View in: PubMed
    Score: 0.027
  13. TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI. Nat Cell Biol. 2010 Mar; 12(3):286-93.
    View in: PubMed
    Score: 0.025
  14. The tale of transforming growth factor-beta (TGFbeta) signaling: a soign? enigma. IUBMB Life. 2009 Oct; 61(10):929-39.
    View in: PubMed
    Score: 0.025
  15. Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions. Oncogene. 2009 Aug 20; 28(33):2999-3007.
    View in: PubMed
    Score: 0.024
  16. Transforming growth factor beta (TGFbeta)-induced apoptosis: the rise & fall of Bim. Cell Cycle. 2009 Jan 01; 8(1):11-7.
    View in: PubMed
    Score: 0.023
  17. TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2. EMBO Rep. 2008 Oct; 9(10):990-7.
    View in: PubMed
    Score: 0.023
  18. The inhibitory effects of Disabled-2 (Dab2) on Wnt signaling are mediated through Axin. Oncogene. 2008 Mar 20; 27(13):1865-75.
    View in: PubMed
    Score: 0.022
  19. Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. J Biol Chem. 2006 Jan 13; 281(2):813-23.
    View in: PubMed
    Score: 0.019
  20. Disabled-2 (Dab2) mediates transforming growth factor beta (TGFbeta)-stimulated fibronectin synthesis through TGFbeta-activated kinase 1 and activation of the JNK pathway. J Biol Chem. 2005 Jul 08; 280(27):25920-7.
    View in: PubMed
    Score: 0.018
  21. Disabled-2 (Dab2) is required for transforming growth factor beta-induced epithelial to mesenchymal transition (EMT). J Biol Chem. 2005 Apr 29; 280(17):17540-8.
    View in: PubMed
    Score: 0.018
  22. Wnt signaling: physiology and pathology. Growth Factors. 2004 Sep; 22(3):141-50.
    View in: PubMed
    Score: 0.017
  23. Regulation of the Wnt signaling pathway by disabled-2 (Dab2). EMBO J. 2003 Jun 16; 22(12):3084-94.
    View in: PubMed
    Score: 0.016
  24. Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes. J Biol Chem. 2003 May 16; 278(20):18069-77.
    View in: PubMed
    Score: 0.016
  25. Staphylococcus aureus peptidoglycan (PGN) induces pathogenic autoantibody production via autoreactive B cell receptor clonal selection, implications in systemic lupus erythematosus. J Autoimmun. 2022 07; 131:102860.
    View in: PubMed
    Score: 0.015
  26. The role of disabled-2 (Dab2) in diseases. Gene. 2021 Feb 15; 769:145202.
    View in: PubMed
    Score: 0.013
  27. Analysis of TGF-beta-mediated synthesis of extracellular matrix components. Methods Mol Biol. 2000; 142:55-65.
    View in: PubMed
    Score: 0.013
  28. Promoter analysis of TGF-beta responsive genes by transient transfection and deletional/mutational analysis. Methods Mol Biol. 2000; 142:79-95.
    View in: PubMed
    Score: 0.013
  29. Regulation of AP-1 activity by TGF-beta. Methods Mol Biol. 2000; 142:97-108.
    View in: PubMed
    Score: 0.013
  30. Analysis of TGF-beta-inducible apoptosis. Methods Mol Biol. 2000; 142:149-67.
    View in: PubMed
    Score: 0.013
  31. Transforming growth factor beta induces caspase 3-independent cleavage of alphaII-spectrin (alpha-fodrin) coincident with apoptosis. J Biol Chem. 1999 Aug 13; 274(33):23256-62.
    View in: PubMed
    Score: 0.012
  32. Transforming growth factor beta regulates clusterin gene expression via modulation of transcription factor c-Fos. Eur J Biochem. 1999 Jul; 263(2):534-42.
    View in: PubMed
    Score: 0.012
  33. Caspase inhibitor BD-fmk distinguishes transforming growth factor beta-induced apoptosis from growth inhibition. Cell Growth Differ. 1998 Oct; 9(10):869-75.
    View in: PubMed
    Score: 0.012
  34. The Long (lncRNA) and Short (miRNA) of It: TGF?-Mediated Control of RNA-Binding Proteins and Noncoding RNAs. Mol Cancer Res. 2018 04; 16(4):567-579.
    View in: PubMed
    Score: 0.011
  35. Metabolic Labeling and Profiling of Transfer RNAs Using Macroarrays. J Vis Exp. 2018 01 16; (131).
    View in: PubMed
    Score: 0.011
  36. Mechanisms of TGF-beta-induced cell cycle arrest. Miner Electrolyte Metab. 1998; 24(2-3):131-5.
    View in: PubMed
    Score: 0.011
  37. Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma. Nat Commun. 2017 11 16; 8(1):1534.
    View in: PubMed
    Score: 0.011
  38. TGF-? receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis. Sci Signal. 2017 Oct 24; 10(502).
    View in: PubMed
    Score: 0.011
  39. Regulation of clusterin gene expression by transforming growth factor beta. J Biol Chem. 1997 Oct 17; 272(42):26620-6.
    View in: PubMed
    Score: 0.011
  40. Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-? signaling. J Clin Invest. 2017 Apr 03; 127(4):1321-1337.
    View in: PubMed
    Score: 0.010
  41. Surface Expression of TGF? Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer. Cancer Res. 2016 12 15; 76(24):7106-7117.
    View in: PubMed
    Score: 0.010
  42. Transforming growth factor beta (TGF beta)-induced nuclear localization of apolipoprotein J/clusterin in epithelial cells. Biochemistry. 1996 May 14; 35(19):6157-63.
    View in: PubMed
    Score: 0.010
  43. Inhibition of G1 phase cyclin dependent kinases by transforming growth factor beta 1. J Cell Biochem. 1994 Nov; 56(3):418-25.
    View in: PubMed
    Score: 0.009
  44. Neuropilin-2 Is upregulated in lung cancer cells during TGF-?1-induced epithelial-mesenchymal transition. Cancer Res. 2013 Dec 01; 73(23):7111-21.
    View in: PubMed
    Score: 0.008
  45. Release from G1 growth arrest by transforming growth factor beta 1 requires cellular ras activity. J Biol Chem. 1993 Oct 05; 268(28):21448-52.
    View in: PubMed
    Score: 0.008
  46. Transforming growth factor beta 1-mediated inhibition of smooth muscle cell proliferation is associated with a late G1 cell cycle arrest. J Cell Physiol. 1993 Jul; 156(1):48-55.
    View in: PubMed
    Score: 0.008
  47. Loss of transforming growth factor beta 1 (TGF-beta 1)-induced growth arrest and p34cdc2 regulation in ras-transfected epithelial cells. Oncogene. 1992 Aug; 7(8):1549-56.
    View in: PubMed
    Score: 0.008
  48. Myosin II isoform switching mediates invasiveness after TGF-?-induced epithelial-mesenchymal transition. Proc Natl Acad Sci U S A. 2011 Nov 01; 108(44):17991-6.
    View in: PubMed
    Score: 0.007
  49. Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest. Mol Cell Biol. 1991 Mar; 11(3):1185-94.
    View in: PubMed
    Score: 0.007
  50. Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2. Mol Biol Cell. 2010 Nov 15; 21(22):4009-19.
    View in: PubMed
    Score: 0.007
  51. Central role for disabled-2 in mesenchymal stem cardiac protein expression and functional consequences after engraftment in acute myocardial infarction. Stem Cells Dev. 2011 Apr; 20(4):681-93.
    View in: PubMed
    Score: 0.007
  52. Inhibition of mink lung epithelial cell proliferation by transforming growth factor-beta is coupled through a pertussis-toxin-sensitive substrate. Biochem J. 1990 Mar 01; 266(2):537-43.
    View in: PubMed
    Score: 0.006
  53. Distinct pathways regulate transforming growth factor beta 1-stimulated proto-oncogene and extracellular matrix gene expression. J Cell Physiol. 1990 Jan; 142(1):39-45.
    View in: PubMed
    Score: 0.006
  54. Regulation of transforming growth factor beta 1 action by multiple transducing pathways: evidence for both G protein-dependent and -independent signaling. Cancer Res. 1989 Nov 01; 49(21):6024-31.
    View in: PubMed
    Score: 0.006
  55. Transforming growth factor beta 1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s). Biochem J. 1989 Aug 01; 261(3):879-86.
    View in: PubMed
    Score: 0.006
  56. Cell autonomous sorting and surface positioning in the formation of primitive endoderm in embryoid bodies. Genesis. 2007 Jun; 45(6):327-38.
    View in: PubMed
    Score: 0.005
  57. Tumor necrosis factor alpha (TNF-alpha) receptor-II is required for TNF-alpha-induced leukocyte-endothelial interaction in vivo. Blood. 2007 Mar 01; 109(5):1938-44.
    View in: PubMed
    Score: 0.005
  58. The oncoprotein Ski acts as an antagonist of transforming growth factor-beta signaling by suppressing Smad2 phosphorylation. J Biol Chem. 2003 Jul 11; 278(28):26249-57.
    View in: PubMed
    Score: 0.004
  59. Oxidized low density lipoprotein and lysophosphatidylcholine stimulate cell cycle entry in vascular smooth muscle cells. Evidence for release of fibroblast growth factor-2. J Biol Chem. 1996 Jul 26; 271(30):17791-7.
    View in: PubMed
    Score: 0.002
  60. Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFbeta-treated cells. Nature. 1996 Mar 21; 380(6571):262-5.
    View in: PubMed
    Score: 0.002
  61. Effect of alpha-tocopherol on restenosis after angioplasty in a model of experimental atherosclerosis. J Clin Invest. 1995 Mar; 95(3):1018-25.
    View in: PubMed
    Score: 0.002
  62. Interferon alpha/beta modulation of growth-factor-stimulated mitogenicity in AKR-2B fibroblasts. J Cell Physiol. 1989 Dec; 141(3):453-60.
    View in: PubMed
    Score: 0.002
  63. The regulation of cell proliferation by serum growth factors. Ann N Y Acad Sci. 1982 Dec 10; 397:1-10.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.