Steven Shapiro to Animals
This is a "connection" page, showing publications Steven Shapiro has written about Animals.
Connection Strength
1.620
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RIP3-dependent necroptosis contributes to the pathogenesis of chronic obstructive pulmonary disease. JCI Insight. 2021 06 22; 6(12).
Score: 0.057
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Reply to: Quantitative Histology Seriously Flawed by Lack of Lung Volume Measurement. Am J Respir Cell Mol Biol. 2018 02; 58(2):274-275.
Score: 0.045
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Variable Susceptibility to Cigarette Smoke-Induced Emphysema in 34 Inbred Strains of Mice Implicates Abi3bp in Emphysema Susceptibility. Am J Respir Cell Mol Biol. 2017 09; 57(3):367-375.
Score: 0.044
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Macrophage Elastase Induces TRAIL-mediated Tumor Cell Death through Its Carboxy-Terminal Domain. Am J Respir Crit Care Med. 2017 08 01; 196(3):353-363.
Score: 0.043
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Mouse Genome-Wide Association Study of Preclinical Group II Pulmonary Hypertension Identifies Epidermal Growth Factor Receptor. Am J Respir Cell Mol Biol. 2017 04; 56(4):488-496.
Score: 0.042
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Automated Measurement of Blood Vessels in Tissues from Microscopy Images. Curr Protoc Cytom. 2016 10 10; 78:12.44.1-12.44.13.
Score: 0.041
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The receptor for advanced glycation end products (RAGE) contributes to the progression of emphysema in mice. PLoS One. 2015; 10(3):e0118979.
Score: 0.037
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Macrophage elastase suppresses white adipose tissue expansion with cigarette smoking. Am J Respir Cell Mol Biol. 2014 Dec; 51(6):822-9.
Score: 0.036
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A protean protease: MMP-12 fights viruses as a protease and a transcription factor. Nat Med. 2014 May; 20(5):470-2.
Score: 0.035
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PPAR? in emphysema: blunts the damage and triggers repair? J Clin Invest. 2014 Mar; 124(3):978-80.
Score: 0.034
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Emerging genetics of COPD. EMBO Mol Med. 2012 Nov; 4(11):1144-55.
Score: 0.031
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CD45/CD11b positive subsets of adult lung anchorage-independent cells harness epithelial stem cells in culture. J Tissue Eng Regen Med. 2013 Jul; 7(7):572-83.
Score: 0.030
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Merging personalized medicine and biology of aging in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2011 Oct 15; 184(8):864-6.
Score: 0.029
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NET loss of air in cystic fibrosis. Nat Med. 2010 Sep; 16(9):967-9.
Score: 0.027
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Cigarette smoke inhibits engulfment of apoptotic cells by macrophages through inhibition of actin rearrangement. Am J Respir Cell Mol Biol. 2011 Apr; 44(4):474-82.
Score: 0.026
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A survey of airway responsiveness in 36 inbred mouse strains facilitates gene mapping studies and identification of quantitative trait loci. Mol Genet Genomics. 2010 Apr; 283(4):317-26.
Score: 0.026
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Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth. Nat Med. 2010 Feb; 16(2):219-23.
Score: 0.026
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Macrophage elastase kills bacteria within murine macrophages. Nature. 2009 Jul 30; 460(7255):637-41.
Score: 0.025
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Epithelial cell apoptosis causes acute lung injury masquerading as emphysema. Am J Respir Cell Mol Biol. 2009 Oct; 41(4):407-14.
Score: 0.024
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Lung biology research 2008: revolution in the midst of a gathering storm. Am J Respir Cell Mol Biol. 2008 Oct; 39(4):i-ii.
Score: 0.023
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Cigarette smoke exposure impairs dendritic cell maturation and T cell proliferation in thoracic lymph nodes of mice. J Immunol. 2008 May 15; 180(10):6623-8.
Score: 0.023
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Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury. Am J Respir Cell Mol Biol. 2008 Jul; 39(1):53-60.
Score: 0.022
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The use of transgenic mice for modeling airways disease. Pulm Pharmacol Ther. 2008 Oct; 21(5):699-701.
Score: 0.022
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CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. J Immunol. 2007 Jun 15; 178(12):8090-6.
Score: 0.021
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Lung turns to AA (adenosine analogues) to dry out. Nat Med. 2007 Apr; 13(4):406-8.
Score: 0.021
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Animal models of asthma: Pro: Allergic avoidance of animal (model[s]) is not an option. Am J Respir Crit Care Med. 2006 Dec 01; 174(11):1171-3.
Score: 0.021
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Stage-specific effects of cAMP signaling during distal lung epithelial development. J Biol Chem. 2006 Dec 15; 281(50):38894-904.
Score: 0.020
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Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases. Cancer Res. 2006 Jun 15; 66(12):6149-55.
Score: 0.020
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Elastin fragments drive disease progression in a murine model of emphysema. J Clin Invest. 2006 Mar; 116(3):753-9.
Score: 0.020
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Animal models of pulmonary emphysema. Curr Drug Targets Inflamm Allergy. 2005 Dec; 4(6):665-73.
Score: 0.019
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Normal lung development in RAIG1-deficient mice despite unique lung epithelium-specific expression. Am J Respir Cell Mol Biol. 2005 May; 32(5):381-7.
Score: 0.018
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Smoke gets in your cells. Am J Respir Cell Mol Biol. 2004 Nov; 31(5):481-2.
Score: 0.018
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Smoke and mirrors: Mouse models as a reflection of human chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2004 Nov 01; 170(9):929-31.
Score: 0.018
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Membrane-bound matrix metalloproteinase-8 on activated polymorphonuclear cells is a potent, tissue inhibitor of metalloproteinase-resistant collagenase and serpinase. J Immunol. 2004 Jun 15; 172(12):7791-803.
Score: 0.017
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Influenza and asthma: adding to the respiratory burden. Nat Immunol. 2004 Mar; 5(3):243-4.
Score: 0.017
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The bone marrow leaves its scar: new concepts in pulmonary fibrosis. J Clin Invest. 2004 Jan; 113(2):180-2.
Score: 0.017
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Neutrophil elastase contributes to cigarette smoke-induced emphysema in mice. Am J Pathol. 2003 Dec; 163(6):2329-35.
Score: 0.017
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The post-genomic red journal: charting the path from hope (not hype) to cure. Am J Respir Cell Mol Biol. 2003 Oct; 29(4):425-6.
Score: 0.017
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Inducible expression of tissue inhibitor of metalloproteinases-resistant matrix metalloproteinase-9 on the cell surface of neutrophils. Am J Respir Cell Mol Biol. 2003 Sep; 29(3 Pt 1):283-94.
Score: 0.016
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Immunology: Mobilizing the army. Nature. 2003 Jan 16; 421(6920):223-4.
Score: 0.016
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Lysyl oxidase is required for vascular and diaphragmatic development in mice. J Biol Chem. 2003 Apr 18; 278(16):14387-93.
Score: 0.016
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ADAM-33 surfaces as an asthma gene. N Engl J Med. 2002 Sep 19; 347(12):936-8.
Score: 0.015
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Cigarette smoking is a secondary cause of folliculin loss. Thorax. 2023 Apr; 78(4):402-408.
Score: 0.015
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Thomas A. Neff lecture. Application of expression profiling to the developing lung: identification of putative regulatory networks controlling matrix production. Chest. 2002 Mar; 121(3 Suppl):42S-44S.
Score: 0.015
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Extracellular Release of Mitochondrial DNA: Triggered by Cigarette Smoke and Detected in COPD. Cells. 2022 01 22; 11(3).
Score: 0.015
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Matrix Metalloproteinase MMP-12 Promotes Macrophage Transmigration Across Intestinal Epithelial Tight Junctions and Increases Severity of Experimental Colitis. J Crohns Colitis. 2021 Oct 07; 15(10):1751-1765.
Score: 0.014
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Alveolar Macrophages Inherently Express Programmed Death-1 Ligand 1 for Optimal Protective Immunity and Tolerance. J Immunol. 2021 07 01; 207(1):110-114.
Score: 0.014
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PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis. JCI Insight. 2021 03 08; 6(5).
Score: 0.014
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Dichloroacetate-induced metabolic reprogramming improves lifespan in a Drosophila model of surviving sepsis. PLoS One. 2020; 15(11):e0241122.
Score: 0.014
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Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer. J Immunother Cancer. 2020 05; 8(1).
Score: 0.013
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FSTL-1 Attenuation Causes Spontaneous Smoke-Resistant Pulmonary Emphysema. Am J Respir Crit Care Med. 2020 04 15; 201(8):934-945.
Score: 0.013
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Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance. Nat Commun. 2019 11 22; 10(1):5324.
Score: 0.013
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Alveolar Macrophage Apoptosis-associated Bacterial Killing Helps Prevent Murine Pneumonia. Am J Respir Crit Care Med. 2019 07 01; 200(1):84-97.
Score: 0.012
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Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages. Am J Respir Crit Care Med. 2017 10 01; 196(7):845-855.
Score: 0.011
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Development of a Mouse Model of Metabolic Syndrome, Pulmonary Hypertension, and Heart Failure with Preserved Ejection Fraction. Am J Respir Cell Mol Biol. 2017 04; 56(4):497-505.
Score: 0.011
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Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy. J Biol Chem. 2015 Dec 11; 290(50):29742-57.
Score: 0.010
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Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer. Cancer Res. 2015 Aug 15; 75(16):3209-15.
Score: 0.009
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Airway epithelial cell PPAR? modulates cigarette smoke-induced chemokine expression and emphysema susceptibility in mice. Am J Physiol Lung Cell Mol Physiol. 2015 Aug 01; 309(3):L293-304.
Score: 0.009
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Differential roles of STAT3 in the initiation and growth of lung cancer. Oncogene. 2015 Jul; 34(29):3804-3814.
Score: 0.009
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Effects of intra-abdominal sepsis on atherosclerosis in mice. Crit Care. 2014 Sep 03; 18(5):469.
Score: 0.009
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Authors' response. Crit Care. 2014; 18(6):645.
Score: 0.008
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Investigating the role of DNA damage in tobacco smoking-induced spine degeneration. Spine J. 2014 Mar 01; 14(3):416-23.
Score: 0.008
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Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses. J Biol Chem. 2013 May 17; 288(20):14647-14656.
Score: 0.008
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Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013; 8(2):e56179.
Score: 0.008
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Cigarette smoking affects oxidative protein folding in endoplasmic reticulum by modifying protein disulfide isomerase. FASEB J. 2013 Mar; 27(3):965-77.
Score: 0.008
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Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoid. Matrix Biol. 2012 Jan; 31(1):38-44.
Score: 0.007
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Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12. Am J Physiol Lung Cell Mol Physiol. 2011 Oct; 301(4):L519-26.
Score: 0.007
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Cell plasticity in lung injury and repair: report from an NHLBI workshop, April 19-20, 2010. Proc Am Thorac Soc. 2011 Jun; 8(3):215-22.
Score: 0.007
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IL-17RA is required for CCL2 expression, macrophage recruitment, and emphysema in response to cigarette smoke. PLoS One. 2011; 6(5):e20333.
Score: 0.007
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CX3CR1+ lung mononuclear phagocytes spatially confined to the interstitium produce TNF-a and IL-6 and promote cigarette smoke-induced emphysema. J Immunol. 2011 Mar 01; 186(5):3206-14.
Score: 0.007
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Comparison of unrestrained plethysmography and forced oscillation for identifying genetic variability of airway responsiveness in inbred mice. Physiol Genomics. 2011 Jan 07; 43(1):1-11.
Score: 0.007
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Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nat Med. 2010 Jul; 16(7):767-73.
Score: 0.007
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The role of the receptor for advanced glycation end-products in a murine model of silicosis. PLoS One. 2010 Mar 19; 5(3):e9604.
Score: 0.006
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Osteoclasts are important for bone angiogenesis. Blood. 2010 Jan 07; 115(1):140-9.
Score: 0.006
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MMP-8 promotes polymorphonuclear cell migration through collagen barriers in obliterative bronchiolitis. J Leukoc Biol. 2010 Jan; 87(1):69-77.
Score: 0.006
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Caveolin-1 expression is required for the development of pulmonary emphysema through activation of the ATM-p53-p21 pathway. J Biol Chem. 2009 Feb 27; 284(9):5462-6.
Score: 0.006
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Clarithromycin prevents smoke-induced emphysema in mice. Am J Respir Crit Care Med. 2009 Feb 15; 179(4):271-8.
Score: 0.006
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An official ATS conference proceedings: advances in small-animal imaging application to lung pathophysiology. Proc Am Thorac Soc. 2008 Jul 15; 5(5):591-600.
Score: 0.006
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Cathepsin S deficiency confers protection from neonatal hyperoxia-induced lung injury. Am J Respir Crit Care Med. 2007 Oct 15; 176(8):778-85.
Score: 0.005
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Scavenger Receptors SR-AI/II and MARCO limit pulmonary dendritic cell migration and allergic airway inflammation. J Immunol. 2007 May 01; 178(9):5912-20.
Score: 0.005
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Genomics and proteomics of lung disease: conference summary. Am J Physiol Lung Cell Mol Physiol. 2007 Jul; 293(1):L45-51.
Score: 0.005
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Essential role of MMP-12 in Fas-induced lung fibrosis. Am J Respir Cell Mol Biol. 2007 Aug; 37(2):210-21.
Score: 0.005
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Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8). FASEB J. 2007 Aug; 21(10):2580-91.
Score: 0.005
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Mice lacking neutrophil elastase are resistant to bleomycin-induced pulmonary fibrosis. Am J Pathol. 2007 Jan; 170(1):65-74.
Score: 0.005
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Role of FcRs in animal model of autoimmune bullous pemphigoid. J Immunol. 2006 Sep 01; 177(5):3398-405.
Score: 0.005
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The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2006 Aug; 3(6):502.
Score: 0.005
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Epithelial cell PPARgamma is an endogenous regulator of normal lung maturation and maintenance. Proc Am Thorac Soc. 2006 Aug; 3(6):510-1.
Score: 0.005
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Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy. Immunity. 2006 Aug; 25(2):271-83.
Score: 0.005
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Inhaled recombinant alpha 1-antitrypsin ameliorates cigarette smoke-induced emphysema in the mouse. COPD. 2006 Jun; 3(2):101-8.
Score: 0.005
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Epithelial cell PPAR[gamma] contributes to normal lung maturation. FASEB J. 2006 Jul; 20(9):1507-9.
Score: 0.005
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Neither SP-A nor NH2-terminal domains of SP-A can substitute for SP-D in regulation of alveolar homeostasis. Am J Physiol Lung Cell Mol Physiol. 2006 Aug; 291(2):L181-90.
Score: 0.005
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The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Am J Hum Genet. 2006 Feb; 78(2):253-64.
Score: 0.005
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Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice. Proc Natl Acad Sci U S A. 2005 Nov 01; 102(44):15791-6.
Score: 0.005
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An inhaled matrix metalloprotease inhibitor prevents cigarette smoke-induced emphysema in the mouse. COPD. 2005 Sep; 2(3):303-10.
Score: 0.005
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Matrix metalloproteinase-8 deficiency promotes granulocytic allergen-induced airway inflammation. J Immunol. 2005 Aug 15; 175(4):2589-97.
Score: 0.005
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An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization. FASEB J. 2005 Oct; 19(12):1668-70.
Score: 0.005
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Induction of macrophage elastase (MMP-12) gene expression by statins. J Cell Physiol. 2005 Jul; 204(1):139-45.
Score: 0.005
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NADPH oxidase restrains the matrix metalloproteinase activity of macrophages. J Biol Chem. 2005 Aug 26; 280(34):30201-5.
Score: 0.005
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Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering. Immunity. 2005 Jun; 22(6):679-91.
Score: 0.005
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Surfactant protein-D regulates soluble CD14 through matrix metalloproteinase-12. J Immunol. 2005 Apr 15; 174(8):4953-9.
Score: 0.005
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MMP-12 has a role in abdominal aortic aneurysms in mice. Surgery. 2005 Apr; 137(4):457-62.
Score: 0.005
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Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia. Am J Physiol Heart Circ Physiol. 2005 Aug; 289(2):H558-68.
Score: 0.005
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Analysis of the inflammatory response induced by rhMMP-12 catalytic domain instilled in mouse airways. Int Immunopharmacol. 2005 Mar; 5(3):511-24.
Score: 0.005
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Polymers of Z alpha1-antitrypsin co-localize with neutrophils in emphysematous alveoli and are chemotactic in vivo. Am J Pathol. 2005 Feb; 166(2):377-86.
Score: 0.005
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Accelerated enlargement of experimental abdominal aortic aneurysms in a mouse model of chronic cigarette smoke exposure. J Am Coll Surg. 2004 Dec; 199(6):896-903.
Score: 0.005
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Role of metalloelastase in a model of allergic lung responses induced by cockroach allergen. Am J Pathol. 2004 Dec; 165(6):1921-30.
Score: 0.005
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Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. J Cell Biol. 2004 Nov 22; 167(4):769-81.
Score: 0.004
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Neutrophil elastase (NE)-deficient mice demonstrate a nonredundant role for NE in neutrophil migration, generation of proinflammatory mediators, and phagocytosis in response to zymosan particles in vivo. J Immunol. 2004 Apr 01; 172(7):4493-502.
Score: 0.004
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Matrix metalloproteinase-12 (MMP-12) in osteoclasts: new lesson on the involvement of MMPs in bone resorption. Bone. 2004 Jan; 34(1):37-47.
Score: 0.004
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Loss of collagenase-2 confers increased skin tumor susceptibility to male mice. Nat Genet. 2003 Nov; 35(3):252-7.
Score: 0.004
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Matrilysin-dependent elastolysis by human macrophages. J Exp Med. 2003 Sep 15; 198(6):925-35.
Score: 0.004
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Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice. Am J Respir Cell Mol Biol. 2004 Jan; 30(1):84-90.
Score: 0.004
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Loss of integrin alpha(v)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Nature. 2003 Mar 13; 422(6928):169-73.
Score: 0.004
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Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release. Am J Respir Crit Care Med. 2003 Apr 15; 167(8):1083-9.
Score: 0.004
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Corneal neovascularization after excimer keratectomy wounds in matrilysin-deficient mice. Invest Ophthalmol Vis Sci. 2003 Jan; 44(1):137-44.
Score: 0.004
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Neutrophils from MMP-9- or neutrophil elastase-deficient mice show no defect in transendothelial migration under flow in vitro. J Leukoc Biol. 2002 May; 71(5):821-8.
Score: 0.004
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Regulation of lutropin circulatory half-life by the mannose/N-acetylgalactosamine-4-SO4 receptor is critical for implantation in vivo. J Clin Invest. 2002 Jan; 109(2):269-76.
Score: 0.004