Yusuf Hannun to Sphingomyelins
This is a "connection" page, showing publications Yusuf Hannun has written about Sphingomyelins.
Connection Strength
3.769
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Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5. J Biol Chem. 2010 Jun 04; 285(23):17993-8002.
Score: 0.330
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Sphingomyelin metabolism at the plasma membrane: implications for bioactive sphingolipids. FEBS Lett. 2010 May 03; 584(9):1887-94.
Score: 0.320
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Differential effects of sphingomyelin hydrolysis and resynthesis on the activation of NF-kappa B in normal and SV40-transformed human fibroblasts. J Biol Chem. 2000 May 12; 275(19):14760-6.
Score: 0.166
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Sphingomyelinase assay using radiolabeled substrate. Methods Enzymol. 2000; 311:164-7.
Score: 0.162
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Synthesis of key precursors of radiolabeled sphingolipids. Methods Enzymol. 2000; 311:518-35.
Score: 0.162
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Activation of the sphingomyelin cycle by brefeldin A: effects of brefeldin A on differentiation and implications for a role for ceramide in regulation of protein trafficking. Cell Growth Differ. 1996 Jun; 7(6):765-74.
Score: 0.126
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Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors. J Biol Chem. 1995 Sep 22; 270(38):22135-42.
Score: 0.120
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Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes. Adv Biol Regul. 2015 Jan; 57:24-41.
Score: 0.113
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Identification of a distinct pool of sphingomyelin involved in the sphingomyelin cycle. J Biol Chem. 1994 Sep 23; 269(38):23530-7.
Score: 0.112
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Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science. 1994 Sep 09; 265(5178):1596-9.
Score: 0.112
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Identification and biochemical characterization of an acid sphingomyelinase-like protein from the bacterial plant pathogen Ralstonia solanacearum that hydrolyzes ATP to AMP but not sphingomyelin to ceramide. PLoS One. 2014; 9(8):e105830.
Score: 0.112
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Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha. J Biol Chem. 1994 Feb 25; 269(8):5757-63.
Score: 0.108
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The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem. 1994 Feb 04; 269(5):3125-8.
Score: 0.108
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Sphingolipid breakdown products: anti-proliferative and tumor-suppressor lipids. Biochim Biophys Acta. 1993 Dec 21; 1154(3-4):223-36.
Score: 0.107
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Tumor necrosis factor-alpha (TNF-alpha) signal transduction through ceramide. Dissociation of growth inhibitory effects of TNF-alpha from activation of nuclear factor-kappa B. J Biol Chem. 1993 Aug 25; 268(24):17762-6.
Score: 0.104
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The sphingomyelin cycle: a prototypic sphingolipid signaling pathway. Adv Lipid Res. 1993; 25:27-41.
Score: 0.100
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Brefeldin A promotes hydrolysis of sphingomyelin. J Biol Chem. 1992 Jul 25; 267(21):14909-11.
Score: 0.097
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Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation. J Biol Chem. 1991 Jan 05; 266(1):484-9.
Score: 0.087
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An overview of sphingolipid metabolism: from synthesis to breakdown. Adv Exp Med Biol. 2010; 688:1-23.
Score: 0.081
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Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation. J Biol Chem. 1989 Nov 15; 264(32):19076-80.
Score: 0.080
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Involvement of acid beta-glucosidase 1 in the salvage pathway of ceramide formation. J Biol Chem. 2009 May 08; 284(19):12972-8.
Score: 0.077
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Ceramide-enriched membrane domains in red blood cells and the mechanism of sphingomyelinase-induced hot-cold hemolysis. Biochemistry. 2008 Oct 28; 47(43):11222-30.
Score: 0.074
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Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells. J Biol Chem. 2008 Sep 26; 283(39):26509-17.
Score: 0.073
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A novel role for protein kinase Cdelta-mediated phosphorylation of acid sphingomyelinase in UV light-induced mitochondrial injury. FASEB J. 2008 Jan; 22(1):183-93.
Score: 0.069
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A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria. Biochem J. 2005 Mar 15; 386(Pt 3):445-51.
Score: 0.058
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Acid and neutral sphingomyelinases: roles and mechanisms of regulation. Biochem Cell Biol. 2004 Feb; 82(1):27-44.
Score: 0.054
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Sphingolipids in vascular biology. Adv Exp Med Biol. 2002; 507:439-44.
Score: 0.047
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Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis. FASEB J. 2001 Dec; 15(14):2669-79.
Score: 0.046
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Rapid replenishment of sphingomyelin in the plasma membrane upon degradation by sphingomyelinase in NIH3T3 cells overexpressing the phosphatidylinositol transfer protein beta. Biochem J. 2000 Mar 01; 346 Pt 2:537-43.
Score: 0.041
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Ceramide in the eukaryotic stress response. Trends Cell Biol. 2000 Feb; 10(2):73-80.
Score: 0.041
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Function of the cloned putative neutral sphingomyelinase as lyso-platelet activating factor-phospholipase C. J Biol Chem. 1999 Dec 31; 274(53):38131-9.
Score: 0.040
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The role of ceramide in cell signaling. Biochim Biophys Acta. 1998 Dec 08; 1436(1-2):233-43.
Score: 0.038
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Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C? J Biol Chem. 1998 Jun 05; 273(23):14550-9.
Score: 0.036
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Phospholipase A2 is necessary for tumor necrosis factor alpha-induced ceramide generation in L929 cells. J Biol Chem. 1997 Jul 04; 272(27):17196-203.
Score: 0.034
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Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis. J Biol Chem. 1997 Apr 11; 272(15):9609-12.
Score: 0.034
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Functions of ceramide in coordinating cellular responses to stress. Science. 1996 Dec 13; 274(5294):1855-9.
Score: 0.033
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Ceramide: an endogenous regulator of apoptosis and growth suppression. Immunol Today. 1995 Jun; 16(6):294-7.
Score: 0.029
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Ceramide: a stress signal and mediator of growth suppression and apoptosis. J Cell Biochem. 1995 Jun; 58(2):191-8.
Score: 0.029
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GPR40/FFA1 and neutral sphingomyelinase are involved in palmitate-boosted inflammatory response of microvascular endothelial cells to LPS. Atherosclerosis. 2015 May; 240(1):163-73.
Score: 0.029
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Role for ceramide in cell cycle arrest. J Biol Chem. 1995 Feb 03; 270(5):2047-52.
Score: 0.029
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Programmed cell death induced by ceramide. Science. 1993 Mar 19; 259(5102):1769-71.
Score: 0.025
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Ceramide stimulates a cytosolic protein phosphatase. J Biol Chem. 1992 Mar 15; 267(8):5048-51.
Score: 0.024
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Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J Biol Chem. 1990 Sep 15; 265(26):15823-31.
Score: 0.021
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Blood sphingolipidomics in healthy humans: impact of sample collection methodology. J Lipid Res. 2010 Oct; 51(10):3074-87.
Score: 0.021
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Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway. Mol Cell Biol. 2007 Apr; 27(8):2997-3007.
Score: 0.017
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Altered adipose and plasma sphingolipid metabolism in obesity: a potential mechanism for cardiovascular and metabolic risk. Diabetes. 2006 Sep; 55(9):2579-87.
Score: 0.016
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Neutral ceramidase encoded by the Asah2 gene is essential for the intestinal degradation of sphingolipids. J Biol Chem. 2006 Mar 17; 281(11):7324-31.
Score: 0.015
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Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity. Proc Natl Acad Sci U S A. 1995 Aug 29; 92(18):8443-7.
Score: 0.007
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Sphingosine inhibits monocyte tissue factor-initiated coagulation by altering factor VII binding. J Biol Chem. 1989 Nov 05; 264(31):18440-4.
Score: 0.005